Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2154	TCMT49	Sodium channel protein type IX alpha subunit	Homo sapiens	IC50: 6 (nM), Ref: 21570288 IC50: 30 (nM), Ref: 23121096
TCMC2154	TCMT51	Sodium channel protein type XI alpha subunit	Homo sapiens	IC50: 30 (nM), Ref: 23121096
TCMC2154	TCMT52	Sodium channel protein type VIII alpha subunit	Homo sapiens	IC50: 30 (nM), Ref: 23121096
TCMC2154	TCMT53	Sodium channel protein type IV alpha subunit	Homo sapiens	IC50: 30 (nM), Ref: 23121096
TCMC2154	TCMT54	Sodium channel protein type III alpha subunit	Homo sapiens	IC50: 30 (nM), Ref: 23121096
TCMC2154	TCMT55	Sodium channel protein type II alpha subunit	Homo sapiens	IC50: 30 (nM), Ref: 23121096
TCMC2154	TCMT56	Sodium channel protein type I alpha subunit	Homo sapiens	IC50: 30 (nM), Ref: 23121096
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC1143	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 860 (nM), Ref: 22668600
TCMC1143	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 830 (nM), Ref: 22668600
TCMC1143	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 780 (nM), Ref: 22668600
TCMC1143	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 750 (nM), Ref: 22668600
TCMC1143	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 610 (nM), Ref: 22668600
TCMC1143	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 650 (nM), Ref: 22668600
TCMC804	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 2000 (nM), Ref: 21561086

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC804	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 62 (ug/ml), Ref: 23356207
TCMC804	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 25 (ug/ml), Ref: 22280816
TCMC804	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 32 (ug/ml), Ref: 15387646 MIC: 62 (ug/ml), Ref: 23356207
TCMC791	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 12.7 (nM), Ref: 17503850