Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1480	TCMT107	Glutamate receptor ionotropic kainate 2	Homo sapiens	Ki: 1106 (nM), Ref: 10821708
TCMC1480	TCMT108	Glutamate receptor ionotropic, AMPA 1	Homo sapiens	Ki: 1360 (nM), Ref: 9357531
TCMC1480	TCMT109	Glutamate receptor ionotropic, AMPA 2	Homo sapiens	Ki: 940 (nM), Ref: 9357531
TCMC1480	TCMT110	Glutamate receptor ionotropic, AMPA 4	Homo sapiens	Ki: 868 (nM), Ref: 9357531
TCMC1480	TCMT111	Glutamate receptor ionotropic kainate 5	Homo sapiens	Ki: 701 (nM), Ref: 9357531
TCMC1480	TCMT660	Metabotropic glutamate receptor 8	Homo sapiens	IC50: 5.7 (nM), Ref: 15603952
TCMC1480	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 613 (nM), Ref: 16250647
TCMC1480	TCMT653	Metabotropic glutamate receptor 1	Homo sapiens	Ki: 250 (nM), Ref: 17725337 Ki: 570 (nM), Ref: 19042134 Ki: 1584.89 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT654	Metabotropic glutamate receptor 5	Homo sapiens	Ki: 390 (nM), Ref: 17725337 Ki: 1160 (nM), Ref: 19042134 Ki: 4677.35 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT657	Metabotropic glutamate receptor 4	Homo sapiens	Ki: 2400 (nM), Ref: 17725337 Ki: 1400 (nM), Ref: 19042134 Ki: 3235.94 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT655	Metabotropic glutamate receptor 2	Homo sapiens	Ki: 6400 (nM), Ref: 19042134 Ki: 1819.7 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT664	Excitatory amino acid transporter 3	Homo sapiens	Ki: 51 (nM), Ref: 18578477
TCMC1480	TCMT656	Metabotropic glutamate receptor 3	Homo sapiens	Ki: 57.54 (nM), Ref: 10.1039/C1MD00186H
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1064	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 2437 (nM), Ref: 20696580
TCMC1064	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 140 (nM), Ref: 20696580
TCMC1064	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 29 (nM), Ref: 20696580

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC2696	TCMT1354	Streptococcus mutans UA159	Streptococcus mutans UA159	MIC: 80 (ug/ml), Ref: 10.1007/s00044-011-9658-5
TCMC1064	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 15 (ug/ml), Ref: 11170636