TCM Putative Target References: TCMH451


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1173
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9430 (nM), Ref: 20185318
Ki: 9430 (nM), Ref: 26498394
TCMC1173
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9780 (nM), Ref: 20185318
Ki: 9780 (nM), Ref: 26498394
TCMC1173
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9870 (nM), Ref: 20185318
TCMC1173
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7410 (nM), Ref: 20185318
TCMC1173
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 8450 (nM), Ref: 20185318
TCMC1173
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7040 (nM), Ref: 20185318
TCMC1173
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2400 (nM), Ref: 20185318
TCMC1173
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2890 (nM), Ref: 20185318
TCMC1187
TCMT151 Protein kinase C alpha Homo sapiens IC50: 1900 (nM), Ref: 9834166
TCMC1495
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 1000 (nM), Ref: 20471252
IC50: 1000 (nM), Ref: 25461324
IC50: 1000 (nM), Ref: 25461324
Ki: 9300 (nM), Ref: 27460668
TCMC1495
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 1000 (nM), Ref: 20471252
Ki: 6800 (nM), Ref: 27460668
TCMC1495
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2037
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 9920 (nM), Ref: 18501600
Ki: 9900 (nM), Ref: 18579385
Ki: 9900 (nM), Ref: 26520662
TCMC2037
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 7120 (nM), Ref: 18501600
Ki: 7100 (nM), Ref: 18579385
Ki: 7100 (nM), Ref: 26520662
TCMC2037
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 8800 (nM), Ref: 18579385
TCMC632
TCMT597 Solute carrier family 28 member 3 Homo sapiens Ki: 2100 (nM), Ref: 23388705
IC50: 3300 (nM), Ref: 23388705
TCMC632
TCMT709 Sodium/nucleoside cotransporter 2 Homo sapiens Ki: 5300 (nM), Ref: 23388705
IC50: 5500 (nM), Ref: 23388705
TCMC632
TCMT710 Sodium/nucleoside cotransporter 1 Homo sapiens Ki: 1800 (nM), Ref: 23388705
IC50: 5500 (nM), Ref: 23388705
TCMC632
TCMT296 Adenosine A1 receptor Homo sapiens IC50: 2.344 (nM), Ref: 26756468
TCMC632
TCMT112 Adenosine A3 receptor Homo sapiens IC50: 1.148 (nM), Ref: 26756468
TCMC1956
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 1080 (nM), Ref: 21282059
TCMC1956
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 470 (nM), Ref: 21282059
TCMC1956
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 4450 (nM), Ref: 21282059
TCMC1956
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4090 (nM), Ref: 21282059
TCMC1956
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 4720 (nM), Ref: 21669522
Ki: 4720 (nM), Ref: 22687439
TCMC1956
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 2450 (nM), Ref: 22687439
TCMC1956
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 690 (nM), Ref: 22668600
TCMC1956
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7870 (nM), Ref: 22668600
TCMC614
TCMT151 Protein kinase C alpha Homo sapiens IC50: 9300 (nM), Ref: 9834166
TCMC916
TCMT161 Hydroxycarboxylic acid receptor 2 Homo sapiens Ki: 4900 (nM), Ref: 21167710
TCMC2105
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1202
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 7030 (nM), Ref: 20185318
TCMC1202
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 7780 (nM), Ref: 20185318
TCMC1202
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 6990 (nM), Ref: 20185318
TCMC1202
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6070 (nM), Ref: 20185318
TCMC1202
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 6130 (nM), Ref: 20185318
TCMC1202
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9970 (nM), Ref: 20185318
TCMC1202
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 4080 (nM), Ref: 20185318
TCMC1202
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 9800 (nM), Ref: 20185318
TCMC1202
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 7490 (nM), Ref: 20185318
TCMC1202
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2250 (nM), Ref: 20185318
TCMC1202
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3200 (nM), Ref: 20185318
TCMC1202
TCMT822 Alpha-(1,3)-fucosyltransferase 7 Homo sapiens IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC2111
TCMT614 Egl nine homolog 1 Homo sapiens IC50: 3000 (nM), Ref: 18942826
TCMC1839
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 9800 (nM), Ref: 18501600
Ki: 9800 (nM), Ref: 18579385
Ki: 920 (nM), Ref: 20185318
TCMC1839
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4800 (nM), Ref: 18579385
Ki: 6270 (nM), Ref: 20185318
TCMC1839
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 9200 (nM), Ref: 18579385
Ki: 3670 (nM), Ref: 20185318
TCMC1839
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 6160 (nM), Ref: 20185318
TCMC1839
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 3730 (nM), Ref: 20185318
TCMC1839
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 4080 (nM), Ref: 20185318
TCMC1839
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 5700 (nM), Ref: 20185318
TCMC1839
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 7130 (nM), Ref: 20185318
TCMC1839
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 7780 (nM), Ref: 20185318
TCMC1839
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 6610 (nM), Ref: 20185318
TCMC1839
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 870 (nM), Ref: 20185318
TCMC1788
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT126 Telomerase reverse transcriptase Homo sapiens IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788
TCMT297 Fatty acid binding protein adipocyte Homo sapiens Ki: 1500 (nM), Ref: 27460668
TCMC2201
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 8700 (nM), Ref: 21332115
TCMC1611
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1611
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2209
TCMT597 Solute carrier family 28 member 3 Homo sapiens Ki: 3400 (nM), Ref: 23388705
IC50: 5400 (nM), Ref: 23388705
TCMC2209
TCMT710 Sodium/nucleoside cotransporter 1 Homo sapiens Ki: 5200 (nM), Ref: 23388705
IC50: 5800 (nM), Ref: 23388705
TCMC770
TCMT588 D-amino-acid oxidase Homo sapiens Ki: 7000 (nM), Ref: 23391306
IC50: 2089.3 (nM), Ref: 23631755
Ki: 2000 (nM), Ref: 23631755
TCMC1378
TCMT306 Matrix metalloproteinase-2 Homo sapiens IC50: 8960 (nM), Ref: 22658537
TCMC1378
TCMT734 Matrix metalloproteinase 12 Homo sapiens IC50: 8220 (nM), Ref: 22658537

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC553
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2491
TCMT1251 Candida albicans Candida albicans MIC: 3.2 (ug/ml), Ref: 9873584
TCMC614
TCMT1454 Bacillus subtilis Bacillus subtilis IC50: 98.5 (ug/ml), Ref: 25981688
TCMC1830
TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214
TCMC1202
TCMT1178 Actinomyces viscosus Actinomyces viscosus MIC: 78 (ug/ml), Ref: 8904847
TCMC1202
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 14.8 (ug/ml), Ref: 15844943
TCMC1788
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 24103427
TCMC1776
TCMT1253 Penicillium chrysogenum Penicillium chrysogenum MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC1047
TCMT1464 Hepatitis B virus Hepatitis B virus IC50: 50 (nM), Ref: 24549242