Target Reference

Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1297	TCMT632	Purine nucleoside phosphorylase	Homo sapiens	Ki: 5000 (nM), Ref: 31484
TCMC1537	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 5930 (nM), Ref: 19846303
TCMC1537	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 630 (nM), Ref: 21561086
TCMC1786	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3900 (nM), Ref: 16580200 IC50: 7600 (nM), Ref: 18798681 IC50: 4200 (nM), Ref: 19702283 IC50: 3840 (nM), Ref: 22044245 IC50: 5600 (nM), Ref: 22690646 IC50: 9500 (nM), Ref: 21453996 Ki: 6000 (nM), Ref: 21453996 IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2600 (nM), Ref: 23357636 IC50: 1100 (nM), Ref: 23434422 IC50: 3020 (nM), Ref: 23942421 IC50: 2010 (nM), Ref: 24090912 IC50: 1900 (nM), Ref: 24684845 IC50: 3020 (nM), Ref: 25497963 IC50: 9500 (nM), Ref: 25264584 Ki: 6000 (nM), Ref: 25264584 IC50: 1030 (nM), Ref: 25595683 IC50: 1170 (nM), Ref: 25600405 IC50: 3020 (nM), Ref: 25872983 IC50: 1000 (nM), Ref: 26083682 IC50: 1536 (nM), Ref: 26100442 IC50: 700 (nM), Ref: 26115570 IC50: 700 (nM), Ref: 26253631 IC50: 1536 (nM), Ref: 26481657 IC50: 730 (nM), Ref: 26711144 IC50: 3020 (nM), Ref: 26774579 IC50: 1536 (nM), Ref: 27123900
TCMC1786	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 4000 (nM), Ref: 21561086 Ki: 3560 (nM), Ref: 21561086 Ki: 660 (nM), Ref: 21561086 Ki: 940 (nM), Ref: 21561086 Ki: 160 (nM), Ref: 21561086 Ki: 72 (nM), Ref: 21561086 IC50: 90 (nM), Ref: 21561086
TCMC1786	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 4230 (nM), Ref: 24684845 IC50: 4440 (nM), Ref: 25497963 IC50: 5460 (nM), Ref: 26100442 IC50: 5460 (nM), Ref: 26481657 IC50: 5460 (nM), Ref: 27123900
TCMC1786	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 980 (nM), Ref: 25497963
TCMC2209	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 3400 (nM), Ref: 23388705 IC50: 5400 (nM), Ref: 23388705
TCMC2209	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 5200 (nM), Ref: 23388705 IC50: 5800 (nM), Ref: 23388705
TCMC2216	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3600 (nM), Ref: 17489632 IC50: 3100 (nM), Ref: 18798681 IC50: 3600 (nM), Ref: 19008110 IC50: 3600 (nM), Ref: 17125223 IC50: 3800 (nM), Ref: 19846295 IC50: 3900 (nM), Ref: 19632832 IC50: 3600 (nM), Ref: 19836230 IC50: 3100 (nM), Ref: 21555221 IC50: 3600 (nM), Ref: 21571537 IC50: 3100 (nM), Ref: 22940448 IC50: 2300 (nM), Ref: 21453996 Ki: 3400 (nM), Ref: 21453996 IC50: 3600 (nM), Ref: 23022281 IC50: 3080 (nM), Ref: 23141910 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2750 (nM), Ref: 23387824 IC50: 4120 (nM), Ref: 24224843 IC50: 4000 (nM), Ref: 24953600 IC50: 3500 (nM), Ref: 25559759 IC50: 3400 (nM), Ref: 25907369 Ki: 6400 (nM), Ref: 25907369 IC50: 5200 (nM), Ref: 26841168

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Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1537	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 21288041
TCMC1537	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC1786	TCMT1107	Protease	Human immunodeficiency virus 1	IC50: 10 (ug/ml), Ref: 10691716
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC1786	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 21.8 (ug/ml), Ref: 9748372
TCMC1786	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC2216	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 6.5 (ug/ml), Ref: 9748372
TCMC2216	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 100 (ug/ml), Ref: 20542692
TCMC2216	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041

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TCM Putative Target References: TCMH2261

Targeted Human Proteins by the Ingredients of Prescription

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription