TCM Putative Target References: TCMH1939


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1495
 TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 1000 (nM), Ref: 20471252
IC50: 1000 (nM), Ref: 25461324
IC50: 1000 (nM), Ref: 25461324
Ki: 9300 (nM), Ref: 27460668
TCMC1495
 TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 1000 (nM), Ref: 20471252
Ki: 6800 (nM), Ref: 27460668
TCMC1495
 TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
 TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
 TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715
 TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715
 TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 3100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715
 TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 1600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2126
 TCMT210 Carboxylesterase 2 Homo sapiens Ki: 1410 (nM), Ref: 23286284
TCMC2126
 TCMT171 Protein-tyrosine phosphatase 1C Homo sapiens IC50: 1970 (nM), Ref: 23957426
TCMC2126
 TCMT233 Protein-tyrosine phosphatase 2C Homo sapiens IC50: 2570 (nM), Ref: 23957426
TCMC876
 TCMT560 Coagulation factor X Homo sapiens IC50: 720 (nM), Ref: 9834152
Ki: 450 (nM), Ref: 9834152
TCMC1624
 TCMT560 Coagulation factor X Homo sapiens IC50: 280 (nM), Ref: 9834152
Ki: 690 (nM), Ref: 9834152
TCMC1102
 TCMT265 Glycogen synthase kinase-3 beta Homo sapiens IC50: 7500 (nM), Ref: 16610779
TCMC1102
 TCMT752 Casein kinase II alpha Homo sapiens IC50: 40 (nM), Ref: 19414254
TCMC1102
 TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2320 (nM), Ref: 20185318
TCMC1102
 TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2180 (nM), Ref: 20185318
TCMC1102
 TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 9080 (nM), Ref: 20185318
TCMC1102
 TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7590 (nM), Ref: 20185318
TCMC1102
 TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7060 (nM), Ref: 20185318
TCMC1102
 TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6320 (nM), Ref: 20185318
Ki: 8790 (nM), Ref: 22892213
TCMC1102
 TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9370 (nM), Ref: 20185318
TCMC1102
 TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 8910 (nM), Ref: 20185318
TCMC1102
 TCMT753 Mothers against decapentaplegic homolog 3 Homo sapiens IC50: 142 (nM), Ref:
TCMC1102
 TCMT721 Heat shock 70 kDa protein 1 Homo sapiens IC50: 760 (nM), Ref:
TCMC1102
 TCMT189 Dual specificity protein phosphatase 3 Homo sapiens IC50: 1230 (nM), Ref: IC50: 980 (nM), Ref:
TCMC1102
 TCMT223 Aldose reductase Homo sapiens IC50: 200 (nM), Ref: 22261024
TCMC1102
 TCMT479 Serine/threonine-protein kinase AKT Homo sapiens IC50: 3340 (nM), Ref: 22377675
TCMC1102
 TCMT436 NUAK family SNF1-like kinase 1 Homo sapiens IC50: 510 (nM), Ref: 22377675
TCMC1102
 TCMT354 Serine/threonine-protein kinase Aurora-A Homo sapiens IC50: 2480 (nM), Ref: 22377675
TCMC1102
 TCMT374 Serine/threonine-protein kinase Aurora-B Homo sapiens IC50: 2500 (nM), Ref: 22377675
TCMC1102
 TCMT626 Serine/threonine-protein kinase B-raf Homo sapiens IC50: 1760 (nM), Ref: 22377675
TCMC1102
 TCMT423 Epidermal growth factor receptor erbB1 Homo sapiens IC50: 690 (nM), Ref: 22377675
TCMC1102
 TCMT418 Ephrin type-B receptor 4 Homo sapiens IC50: 1830 (nM), Ref: 22377675
TCMC1102
 TCMT704 Receptor protein-tyrosine kinase erbB-2 Homo sapiens IC50: 3540 (nM), Ref: 22377675
TCMC1102
 TCMT441 Focal adhesion kinase 1 Homo sapiens IC50: 3110 (nM), Ref: 22377675
TCMC1102
 TCMT369 Insulin-like growth factor I receptor Homo sapiens IC50: 250 (nM), Ref: 22377675
TCMC1102
 TCMT212 Tyrosine-protein kinase SRC Homo sapiens IC50: 800 (nM), Ref: 22377675
TCMC1102
 TCMT370 Vascular endothelial growth factor receptor 2 Homo sapiens IC50: 790 (nM), Ref: 22377675
TCMC1102
 TCMT457 Vascular endothelial growth factor receptor 3 Homo sapiens IC50: 1540 (nM), Ref: 22377675
TCMC1102
 TCMT377 Insulin receptor Homo sapiens IC50: 340 (nM), Ref: 22377675
TCMC1102
 TCMT401 Hepatocyte growth factor receptor Homo sapiens IC50: 580 (nM), Ref: 22377675
TCMC1102
 TCMT536 Platelet-derived growth factor receptor beta Homo sapiens IC50: 1300 (nM), Ref: 22377675
TCMC1102
 TCMT484 Serine/threonine-protein kinase PLK1 Homo sapiens IC50: 3340 (nM), Ref: 22377675
TCMC1102
 TCMT755 Serine/threonine-protein kinase PLK4 Homo sapiens IC50: 2970 (nM), Ref: 22377675
TCMC1102
 TCMT502 Tyrosine-protein kinase TIE-2 Homo sapiens IC50: 260 (nM), Ref: 22377675
TCMC1102
 TCMT756 Mitogen-activated protein kinase kinase kinase 8 Homo sapiens IC50: 2370 (nM), Ref: 22377675
TCMC1102
 TCMT739 G-protein coupled receptor 35 Homo sapiens IC50: 100 (nM), Ref: 24900447
TCMC1102
 TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 8150 (nM), Ref: 22892213
TCMC1102
 TCMT225 Carbonic anhydrase XIII Homo sapiens Ki: 4240 (nM), Ref: 22892213
TCMC1102
 TCMT207 Beta-secretase 1 Homo sapiens IC50: 3900 (nM), Ref: 24835197
TCMC1158
 TCMT207 Beta-secretase 1 Homo sapiens IC50: 3100 (nM), Ref: 24835197
Ki: 6840 (nM), Ref: 24835197
TCMC2105
 TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105
 TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
 TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
 TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
 TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
 TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
 TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
 TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
 TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1202
 TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 7030 (nM), Ref: 20185318
TCMC1202
 TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 7780 (nM), Ref: 20185318
TCMC1202
 TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 6990 (nM), Ref: 20185318
TCMC1202
 TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6070 (nM), Ref: 20185318
TCMC1202
 TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 6130 (nM), Ref: 20185318
TCMC1202
 TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9970 (nM), Ref: 20185318
TCMC1202
 TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 4080 (nM), Ref: 20185318
TCMC1202
 TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 9800 (nM), Ref: 20185318
TCMC1202
 TCMT143 Carbonic anhydrase III Homo sapiens Ki: 7490 (nM), Ref: 20185318
TCMC1202
 TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2250 (nM), Ref: 20185318
TCMC1202
 TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3200 (nM), Ref: 20185318
TCMC1202
 TCMT822 Alpha-(1,3)-fucosyltransferase 7 Homo sapiens IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC2111
 TCMT614 Egl nine homolog 1 Homo sapiens IC50: 3000 (nM), Ref: 18942826
TCMC1966
 TCMT207 Beta-secretase 1 Homo sapiens IC50: 410 (nM), Ref: 24835197
TCMC1587
 TCMT210 Carboxylesterase 2 Homo sapiens Ki: 83.7 (nM), Ref: 23286284
Ki: 40 (nM), Ref: 23286284
TCMC1587
 TCMT211 Acyl coenzyme A:cholesterol acyltransferase Homo sapiens Ki: 2530 (nM), Ref: 23286284
TCMC1788
 TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
 TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
 TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
 TCMT126 Telomerase reverse transcriptase Homo sapiens IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788
 TCMT297 Fatty acid binding protein adipocyte Homo sapiens Ki: 1500 (nM), Ref: 27460668
TCMC804
 TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 2000 (nM), Ref: 21561086
TCMC1995
 TCMT661 Glutamate carboxypeptidase II Homo sapiens IC50: 9500 (nM), Ref: 17567119
TCMC392
 TCMT206 Cytochrome P450 2A6 Homo sapiens IC50: 2400 (nM), Ref: 15658857
IC50: 2398.83 (nM), Ref: 19110342
TCMC2127
 TCMT223 Aldose reductase Homo sapiens IC50: 8690 (nM), Ref: 22261024
TCMC2127
 TCMT126 Telomerase reverse transcriptase Homo sapiens IC50: 5000 (nM), Ref: 22044621
IC50: 500 (nM), Ref: 22044621
TCMC2127
 TCMT210 Carboxylesterase 2 Homo sapiens Ki: 69.4 (nM), Ref: 23286284
Ki: 2450 (nM), Ref: 23286284
TCMC2127
 TCMT211 Acyl coenzyme A:cholesterol acyltransferase Homo sapiens Ki: 6890 (nM), Ref: 23286284
TCMC2127
 TCMT171 Protein-tyrosine phosphatase 1C Homo sapiens IC50: 2140 (nM), Ref: 23957426
TCMC2127
 TCMT233 Protein-tyrosine phosphatase 2C Homo sapiens IC50: 2590 (nM), Ref: 23957426
TCMC1611
 TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1611
 TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC254
 TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 7500 (nM), Ref: 15916432
TCMC770
 TCMT588 D-amino-acid oxidase Homo sapiens Ki: 7000 (nM), Ref: 23391306
IC50: 2089.3 (nM), Ref: 23631755
Ki: 2000 (nM), Ref: 23631755

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2107
 TCMT1294 Human parainfluenza virus 3 Human parainfluenza virus 3 IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107
 TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 20542692
TCMC1102
 TCMT1246 Escherichia coli Escherichia coli MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102
 TCMT1412 Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102
 TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.103 (ug/ml), Ref: 11374952
IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102
 TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 0.103 (ug/ml), Ref: 11374952
IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102
 TCMT1458 Filobasidiella neoformans Cryptococcus neoformans IC50: 5.5 (ug/ml), Ref: 12502337
TCMC1830
 TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
 TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
 TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214
TCMC1202
 TCMT1178 Actinomyces viscosus Actinomyces viscosus MIC: 78 (ug/ml), Ref: 8904847
TCMC1202
 TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 14.8 (ug/ml), Ref: 15844943
TCMC1966
 TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 32 (ug/ml), Ref: 11277742
TCMC1966
 TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 27.73 (ug/ml), Ref: 19299148
TCMC1788
 TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 24103427
TCMC804
 TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 32 (ug/ml), Ref: 15387646
MIC: 62 (ug/ml), Ref: 23356207
TCMC804
 TCMT1181 Mycobacterium tuberculosis H37Ra Mycobacterium tuberculosis H37Ra MIC: 25 (ug/ml), Ref: 22280816
TCMC804
 TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 32 (ug/ml), Ref: 15387646
MIC: 62 (ug/ml), Ref: 23356207