Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2093	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 57 (nM), Ref: 17149865
TCMC2093	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 68 (nM), Ref: 17149865
TCMC758	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	Ki: 175.5 (nM), Ref: 25978962 IC50: 488.8 (nM), Ref: 25978962
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1551	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1900 (nM), Ref: 16248836 Ki: 1900 (nM), Ref: 16248836 Ki: 800 (nM), Ref: 16248836 Ki: 250 (nM), Ref: 22696418
TCMC1551	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 760 (nM), Ref: 23746477
TCMC1551	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 40 (nM), Ref: 22696418
TCMC679	TCMT624	Heat shock protein HSP 90-beta	Homo sapiens	IC50: 930 (nM), Ref: 7853008 IC50: 1410 (nM), Ref: IC50: 24 (nM), Ref: 10.1007/s00044-012-0301-x IC50: 90 (nM), Ref: 19734910
TCMC679	TCMT619	Heat shock protein HSP 90-alpha	Homo sapiens	Ki: 680 (nM), Ref:
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477
TCMC1343	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 90 (nM), Ref: 18501600 Ki: 90 (nM), Ref: 18579385
TCMC1343	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7800 (nM), Ref: 18579385
TCMC1343	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8200 (nM), Ref: 18579385

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1381	TCMT1251	Candida albicans	Candida albicans	IC50: 3 (ug/ml), Ref: 17112640 IC50: 2 (ug/ml), Ref: 12502337
TCMC1381	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 7 (ug/ml), Ref: 17112640 IC50: 45 (ug/ml), Ref: 12502337
TCMC1381	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 31.2 (ug/ml), Ref: 18951808
TCMC1381	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 31.2 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.62 (ug/ml), Ref: 22169259
TCMC1381	TCMT1246	Escherichia coli	Escherichia coli	MIC: 2 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051 MIC: 0.25 (ug/ml), Ref: 20160051 MIC: 8 (ug/ml), Ref: 20160051
TCMC1381	TCMT1179	Escherichia coli ATCC 8739	Escherichia coli ATCC 8739	MIC: 8 (ug/ml), Ref: 20160051
TCMC1381	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 16 (ug/ml), Ref: 20160051 MIC: 32 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051 MIC: 8 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051
TCMC1381	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 32 (ug/ml), Ref: 20160051 MIC: 4 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051
TCMC1381	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 64 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051
TCMC1381	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 64 (ug/ml), Ref: 20160051 MIC: 4 (ug/ml), Ref: 20160051
TCMC1381	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 8 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051 MIC: 1 (ug/ml), Ref: 20160051
TCMC1381	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 18 (ug/ml), Ref: 22280816
TCMC2362	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 32 (ug/ml), Ref: 20427099
TCMC2362	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 1 (ug/ml), Ref: 20427099
TCMC2362	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 1 (ug/ml), Ref: 20427099
TCMC2362	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 1 (ug/ml), Ref: 20427099
TCMC2374	TCMT1251	Candida albicans	Candida albicans	IC50: 5 (ug/ml), Ref: 12502337
TCMC2374	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 7.5 (ug/ml), Ref: 12502337
TCMC2093	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 12932139
TCMC2093	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 12932139
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC2544	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.2 (ug/ml), Ref: 7964799
TCMC2544	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 50 (ug/ml), Ref: 7964799
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1955	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4.17 (ug/ml), Ref: 24549242
TCMC1551	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 20832915
TCMC2747	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MBC: 16 (ug/ml), Ref: 15958589 MIC: 16 (ug/ml), Ref: 15958589
TCMC2747	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MBC: 64 (ug/ml), Ref: 15958589 MIC: 32 (ug/ml), Ref: 15958589
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915
TCMC2818	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 64 (ug/ml), Ref: 20427099