TCM Putative Target References: TCMH1920


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.
Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1495
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 1000 (nM), Ref: 20471252
IC50: 1000 (nM), Ref: 25461324
IC50: 1000 (nM), Ref: 25461324
Ki: 9300 (nM), Ref: 27460668
TCMC1495
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 1000 (nM), Ref: 20471252
Ki: 6800 (nM), Ref: 27460668
TCMC1495
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1397
TCMT34 Cytochrome P450 2D6 Homo sapiens IC50: 4630 (nM), Ref: 15270556
TCMC1397
TCMT61 Induced myeloid leukemia cell differentiation protein Mcl-1 Homo sapiens IC50: 5405 (nM), Ref:
TCMC1293
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2940 (nM), Ref: 19231207
TCMC1480
TCMT107 Glutamate receptor ionotropic kainate 2 Homo sapiens Ki: 1106 (nM), Ref: 10821708
TCMC1480
TCMT108 Glutamate receptor ionotropic, AMPA 1 Homo sapiens Ki: 1360 (nM), Ref: 9357531
TCMC1480
TCMT109 Glutamate receptor ionotropic, AMPA 2 Homo sapiens Ki: 940 (nM), Ref: 9357531
TCMC1480
TCMT110 Glutamate receptor ionotropic, AMPA 4 Homo sapiens Ki: 868 (nM), Ref: 9357531
TCMC1480
TCMT111 Glutamate receptor ionotropic kainate 5 Homo sapiens Ki: 701 (nM), Ref: 9357531
TCMC1480
TCMT660 Metabotropic glutamate receptor 8 Homo sapiens IC50: 5.7 (nM), Ref: 15603952
TCMC1480
TCMT112 Adenosine A3 receptor Homo sapiens IC50: 613 (nM), Ref: 16250647
TCMC1480
TCMT653 Metabotropic glutamate receptor 1 Homo sapiens Ki: 250 (nM), Ref: 17725337
Ki: 570 (nM), Ref: 19042134
Ki: 1584.89 (nM), Ref: 10.1039/C1MD00186H
TCMC1480
TCMT654 Metabotropic glutamate receptor 5 Homo sapiens Ki: 390 (nM), Ref: 17725337
Ki: 1160 (nM), Ref: 19042134
Ki: 4677.35 (nM), Ref: 10.1039/C1MD00186H
TCMC1480
TCMT657 Metabotropic glutamate receptor 4 Homo sapiens Ki: 2400 (nM), Ref: 17725337
Ki: 1400 (nM), Ref: 19042134
Ki: 3235.94 (nM), Ref: 10.1039/C1MD00186H
TCMC1480
TCMT655 Metabotropic glutamate receptor 2 Homo sapiens Ki: 6400 (nM), Ref: 19042134
Ki: 1819.7 (nM), Ref: 10.1039/C1MD00186H
TCMC1480
TCMT664 Excitatory amino acid transporter 3 Homo sapiens Ki: 51 (nM), Ref: 18578477
TCMC1480
TCMT656 Metabotropic glutamate receptor 3 Homo sapiens Ki: 57.54 (nM), Ref: 10.1039/C1MD00186H
TCMC2225
TCMT594 Platelet activating factor receptor Homo sapiens Ki: 1000 (nM), Ref: 1404229
TCMC1830
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1105
TCMT752 Casein kinase II alpha Homo sapiens IC50: 2000 (nM), Ref: 19414254
TCMC1105
TCMT239 Serine/threonine-protein kinase PIM1 Homo sapiens IC50: 2500 (nM), Ref: 27173800
TCMC2201
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 8700 (nM), Ref: 21332115
TCMC2180
TCMT302 HMG-CoA reductase Homo sapiens IC50: 5860 (nM), Ref: 25311563
IC50: 36.31 (nM), Ref: 25311563

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC553
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC1352
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 62.5 (ug/ml), Ref: 18823782
TCMC1352
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 62.5 (ug/ml), Ref: 18823782
TCMC2477
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 72.5 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1767
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 60 (ug/ml), Ref: 20384293
TCMC1767
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC2529
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 0.404 (ug/ml), Ref: 11421741
IC50: 0.368 (ug/ml), Ref: 11421741
TCMC2529
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.404 (ug/ml), Ref: 11421741
IC50: 0.368 (ug/ml), Ref: 11421741
TCMC1830
TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550
TCMT1393 Vibrio sp. Vibrio sp. MIC: 15 (ug/ml), Ref: 21865038
TCMC495
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 7.33 (ug/ml), Ref: 8759172
IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 7.33 (ug/ml), Ref: 8759172
IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1105
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 16 (ug/ml), Ref: 23534483
TCMC1105
TCMT1176 Streptococcus pneumoniae Streptococcus pneumoniae MIC: 1 (ug/ml), Ref: 23534483
TCMC1105
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 2 (ug/ml), Ref: 23534483
MIC: 4 (ug/ml), Ref: 23534483
TCMC2166
TCMT1211 Fusobacterium nucleatum Fusobacterium nucleatum MIC: 50 (ug/ml), Ref: 8864235
TCMC2166
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1321 Staphylococcus hominis Staphylococcus hominis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1209 Staphylococcus haemolyticus Staphylococcus haemolyticus MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1343 Staphylococcus simulans Staphylococcus simulans MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1344 Staphylococcus sciuri Staphylococcus sciuri MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1251 Candida albicans Candida albicans MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1246 Escherichia coli Escherichia coli MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2035
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC2635
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 0.608 (ug/ml), Ref: 23313632
TCMC2635
TCMT1442 Leishmania donovani Leishmania donovani IC50: 10.9 (ug/ml), Ref: 23313632
TCMC912
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1578
TCMT1408 Colletotrichum gloeosporioides Colletotrichum gloeosporioides IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578
TCMT1245 Phytophthora cactorum Phytophthora cactorum IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC2688
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 50 (ug/ml), Ref: 14969530
TCMC2688
TCMT1282 Colletotrichum orbiculare Colletotrichum orbiculare MIC: 30 (ug/ml), Ref: 14969530
TCMC1889
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2822
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 6.25 (ug/ml), Ref: 17845001
TCMC2542
TCMT1221 Human herpesvirus 4 Human herpesvirus 4 IC50: 8.8 (nM), Ref: 17503850