Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC658	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 122 (nM), Ref: 26125082
TCMC338	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 2490 (nM), Ref: IC50: 3540 (nM), Ref:
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC521	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9650 (nM), Ref: 22892213
TCMC521	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7010 (nM), Ref: 22892213
TCMC521	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4310 (nM), Ref: 22892213
TCMC521	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 3320 (nM), Ref: 22892213
TCMC521	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 830 (nM), Ref: 22892213
TCMC521	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 760 (nM), Ref: 22892213
TCMC730	TCMT87	Cytochrome P450 2C9	Homo sapiens	Ki: 6800 (nM), Ref: 22752007
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1153	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7700 (nM), Ref: 22668600
TCMC1153	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8600 (nM), Ref: 22668600
TCMC1153	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 22668600
TCMC1153	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8700 (nM), Ref: 22668600
TCMC1153	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4800 (nM), Ref: 22668600
TCMC1153	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 7900 (nM), Ref: 22668600
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1064	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 2437 (nM), Ref: 20696580
TCMC1064	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 140 (nM), Ref: 20696580
TCMC1064	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 29 (nM), Ref: 20696580

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2260	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 50 (ug/ml), Ref: 1710653 IC50: 49 (ug/ml), Ref: 1710653
TCMC2233	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 20.85 (ug/ml), Ref: 20116898
TCMC1866	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC658	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 49.81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC892	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 32 (ug/ml), Ref: 23314053
TCMC892	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 23314053
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1033	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 100 (ug/ml), Ref: 10924184
TCMC1033	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10924184
TCMC1033	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 30 (ug/ml), Ref: 18564877
TCMC2642	TCMT1251	Candida albicans	Candida albicans	IC50: 3.5 (ug/ml), Ref: 12088427 MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 12088427 IC50: 2 (ug/ml), Ref: 12088427
TCMC2642	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 2 (ug/ml), Ref: 12088427 MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642	TCMT1355	Rhodococcus equi	Rhodococcus equi	MIC: 10 (ug/ml), Ref: 19639965
TCMC2642	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 12 (ug/ml), Ref: 19874044
TCMC2642	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC2642	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC2667	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 15104489 MIC: 100 (ug/ml), Ref: 20542692
TCMC2086	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 100 (ug/ml), Ref: 10924184
TCMC2086	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10924184
TCMC2044	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 15 (ug/ml), Ref: 9644074 MIC: 15 (ug/ml), Ref: 8904847
TCMC2044	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 15 (ug/ml), Ref: 8904847
TCMC2044	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC90: 16 (ug/ml), Ref: 23127490 MIC90: 8 (ug/ml), Ref: 23127490 MIC: 16 (ug/ml), Ref: 23314053 MIC: 8 (ug/ml), Ref: 23314053
TCMC2044	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC90: 2 (ug/ml), Ref: 23127490 MIC: 2 (ug/ml), Ref: 23314053 MBC: 0.034 (nM), Ref: 22182580
TCMC1064	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 15 (ug/ml), Ref: 11170636
TCMC1047	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 50 (nM), Ref: 24549242
TCMC2044	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MBC: 0.034 (nM), Ref: 22182580