Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC1118	TCMT304	Matrix metalloproteinase 14	Homo sapiens	IC50: 6800 (nM), Ref: 19524436
TCMC1118	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 9600 (nM), Ref: 19524436
TCMC1118	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 757 (nM), Ref: 22225636
TCMC1118	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 1000 (nM), Ref: 22413845 IC50: 1080 (nM), Ref: 22413845 IC50: 1180 (nM), Ref: 22413845 IC50: 1000 (nM), Ref: 10.1039/C0MD00241K
TCMC1118	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 335 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC1118	TCMT2	Microtubule-associated protein tau	Homo sapiens	IC50: 1800 (nM), Ref: 23484434
TCMC1118	TCMT751	Dual-specificity tyrosine-phosphorylation regulated kinase 1A	Homo sapiens	IC50: 330 (nM), Ref: 24188002
TCMC1118	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4600 (nM), Ref: 24878198 IC50: 3000 (nM), Ref: 24878198 IC50: 500 (nM), Ref: 25978520
TCMC1118	TCMT567	DNA (cytosine-5)-methyltransferase 1	Homo sapiens	IC50: 500 (nM), Ref: 25406944
TCMC1118	TCMT232	P-glycoprotein 1	Homo sapiens	IC50: 124.1 (nM), Ref: 25985195 IC50: 122.6 (nM), Ref: 25985195

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1118	TCMT1092	Fatty acid synthase	Plasmodium falciparum	IC50: 0.03 (ug/ml), Ref: 20855214 IC50: 30 (nM), Ref: 24063369
TCMC1118	TCMT1094	3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum	IC50: 0.32 (ug/ml), Ref: 20855214
TCMC1118	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 79 (nM), Ref: 17263522 Ki: 8 (nM), Ref: 17263522
TCMC791	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 12.7 (nM), Ref: 17503850
TCMC1118	TCMT1222	Plasmodium falciparum D6	Plasmodium falciparum D6	IC50: 73 (nM), Ref: 25488841