Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC850	TCMT307	HERG	Homo sapiens	IC50: 4897.79 (nM), Ref: 21185626
TCMC850	TCMT707	Adenosine A2a receptor	Homo sapiens	Ki: 5011.87 (nM), Ref: 21661720 Ki: 9560 (nM), Ref: 23200243 Ki: 2480 (nM), Ref: 23200243
TCMC850	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 7250 (nM), Ref: 23791077
TCMC732	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 5900 (nM), Ref: 21561086
TCMC2216	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3600 (nM), Ref: 17489632 IC50: 3100 (nM), Ref: 18798681 IC50: 3600 (nM), Ref: 19008110 IC50: 3600 (nM), Ref: 17125223 IC50: 3800 (nM), Ref: 19846295 IC50: 3900 (nM), Ref: 19632832 IC50: 3600 (nM), Ref: 19836230 IC50: 3100 (nM), Ref: 21555221 IC50: 3600 (nM), Ref: 21571537 IC50: 3100 (nM), Ref: 22940448 IC50: 2300 (nM), Ref: 21453996 Ki: 3400 (nM), Ref: 21453996 IC50: 3600 (nM), Ref: 23022281 IC50: 3080 (nM), Ref: 23141910 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2750 (nM), Ref: 23387824 IC50: 4120 (nM), Ref: 24224843 IC50: 4000 (nM), Ref: 24953600 IC50: 3500 (nM), Ref: 25559759 IC50: 3400 (nM), Ref: 25907369 Ki: 6400 (nM), Ref: 25907369 IC50: 5200 (nM), Ref: 26841168
TCMC2216	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 1900 (nM), Ref: 20100662
TCMC2216	TCMT102	Low molecular weight phosphotyrosine protein phosphatase	Homo sapiens	IC50: 7200 (nM), Ref: 21453996
TCMC2216	TCMT103	Receptor-type tyrosine-protein phosphatase F (LAR)	Homo sapiens	IC50: 3800 (nM), Ref: 21453996
TCMC2216	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 21561086 Ki: 3700 (nM), Ref: 21561086 Ki: 2100 (nM), Ref: 21561086 Ki: 2800 (nM), Ref: 21561086 Ki: 2000 (nM), Ref: 21561086 IC50: 4000 (nM), Ref: 21561086
TCMC2216	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 2400 (nM), Ref: 23387824
TCMC2216	TCMT150	Nuclear receptor ROR-gamma	Homo sapiens	IC50: 680 (nM), Ref: 10.1039/C3MD00005B IC50: 130 (nM), Ref: 24704616 IC50: 1060 (nM), Ref: 24704616 IC50: 9410 (nM), Ref: 24704616
TCMC350	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 7400 (nM), Ref: 22940448

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1520	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 22963193
TCMC724	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC724	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 8 (ug/ml), Ref: 9748372 IC50: 36 (ug/ml), Ref: 9748372
TCMC724	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 21288041
TCMC724	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 64 (ug/ml), Ref: 21288041
TCMC732	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 9 (ug/ml), Ref: 9748372
TCMC2216	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 6.5 (ug/ml), Ref: 9748372
TCMC2216	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 100 (ug/ml), Ref: 20542692
TCMC2216	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC2807	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 22963193 MIC: 2 (ug/ml), Ref: 22963193