Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC943	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 810 (nM), Ref: 20100662
TCMC943	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 7000 (nM), Ref: 22940448 IC50: 5490 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 5490 (nM), Ref: 10.1007/s00044-010-9529-5
TCMC2126	TCMT210	Carboxylesterase 2	Homo sapiens	Ki: 1410 (nM), Ref: 23286284
TCMC2126	TCMT171	Protein-tyrosine phosphatase 1C	Homo sapiens	IC50: 1970 (nM), Ref: 23957426
TCMC2126	TCMT233	Protein-tyrosine phosphatase 2C	Homo sapiens	IC50: 2570 (nM), Ref: 23957426
TCMC1582	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 4100 (nM), Ref: 22668600
TCMC1582	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 820 (nM), Ref: 22668600
TCMC1582	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5500 (nM), Ref: 22668600
TCMC1582	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 780 (nM), Ref: 22668600
TCMC1582	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3400 (nM), Ref: 22668600
TCMC1582	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2600 (nM), Ref: 22668600
TCMC880	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9910 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 20185318 Ki: 9900 (nM), Ref: 22245047 Ki: 9900 (nM), Ref: 26073005 Ki: 9900 (nM), Ref: 26520662
TCMC880	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4200 (nM), Ref: 18579385 Ki: 4200 (nM), Ref: 20185318
TCMC880	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 18579385 Ki: 8900 (nM), Ref: 20185318
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1834	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9060 (nM), Ref: 21402476
TCMC1834	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 8030 (nM), Ref: 21402476

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2257	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 15.46 (ug/ml), Ref: 20116898
TCMC943	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 8 (ug/ml), Ref: 9748372
TCMC943	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 21288041 MIC: 7 (ug/ml), Ref: 25794790
TCMC943	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 32 (ug/ml), Ref: 21288041
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC1582	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 12.5 (ug/ml), Ref: 18539361
TCMC1582	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 25 (ug/ml), Ref: 18539361
TCMC2257	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 37.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 59.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1767	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 60 (ug/ml), Ref: 20384293
TCMC1767	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2554	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 20702006
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC2648	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 31.2 (ug/ml), Ref: 20702006 MIC: 31.2 (ug/ml), Ref: 24300736
TCMC2648	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 31.2 (ug/ml), Ref: 20702006 MIC: 31.2 (ug/ml), Ref: 24300736
TCMC2648	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 62.5 (ug/ml), Ref: 20702006 MIC: 62.5 (ug/ml), Ref: 24300736
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001