TCM Putative Target References: TCMH486


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.
Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC761
TCMT206 Cytochrome P450 2A6 Homo sapiens IC50: 3920 (nM), Ref: 15658857
TCMC2013
TCMT223 Aldose reductase Homo sapiens IC50: 2700 (nM), Ref: 22261024
TCMC2119
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9140 (nM), Ref: 20185318
TCMC2119
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9010 (nM), Ref: 20185318
TCMC2119
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 8200 (nM), Ref: 20185318
TCMC2119
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7810 (nM), Ref: 20185318
TCMC2119
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7550 (nM), Ref: 20185318
TCMC2119
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 6340 (nM), Ref: 20185318
TCMC2119
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 8580 (nM), Ref: 20185318
TCMC2119
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 3190 (nM), Ref: 20185318
TCMC2119
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 4150 (nM), Ref: 20185318
TCMC1429
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 2700 (nM), Ref: 17378609
TCMC1429
TCMT65 Estradiol 17-beta-dehydrogenase 1 Homo sapiens IC50: 1050 (nM), Ref: 18533708
TCMC1429
TCMT66 Estradiol 17-beta-dehydrogenase 2 Homo sapiens IC50: 360 (nM), Ref: 18533708
TCMC1429
TCMT187 Androgen Receptor Homo sapiens IC50: 9700 (nM), Ref: 19592245
TCMC1429
TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 716 (nM), Ref: 20696580
TCMC1429
TCMT215 Cytochrome P450 1A1 Homo sapiens IC50: 632 (nM), Ref: 20696580
TCMC1429
TCMT257 Cytochrome P450 1B1 Homo sapiens IC50: 47 (nM), Ref: 20696580
TCMC1429
TCMT223 Aldose reductase Homo sapiens IC50: 10000 (nM), Ref: 22261024
TCMC1429
TCMT260 Tyrosine-protein kinase receptor FLT3 Homo sapiens IC50: 2320 (nM), Ref: 23411073
TCMC1429
TCMT591 Estrogen-related receptor alpha Homo sapiens IC50: 9640 (nM), Ref: 23656512
TCMC1429
TCMT261 Death-associated protein kinase 1 Homo sapiens IC50: 10000 (nM), Ref: 26322379
TCMC1429
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 9525.7 (nM), Ref: 26498393
TCMC1429
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 25 (nM), Ref: 26498393
TCMC1429
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 145.9 (nM), Ref: 26498393
TCMC1429
TCMT159 Tyrosinase Homo sapiens IC50: 1000 (nM), Ref: 26841168
TCMC1786
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 3900 (nM), Ref: 16580200
IC50: 7600 (nM), Ref: 18798681
IC50: 4200 (nM), Ref: 19702283
IC50: 3840 (nM), Ref: 22044245
IC50: 5600 (nM), Ref: 22690646
IC50: 9500 (nM), Ref: 21453996
Ki: 6000 (nM), Ref: 21453996
IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 2600 (nM), Ref: 23357636
IC50: 1100 (nM), Ref: 23434422
IC50: 3020 (nM), Ref: 23942421
IC50: 2010 (nM), Ref: 24090912
IC50: 1900 (nM), Ref: 24684845
IC50: 3020 (nM), Ref: 25497963
IC50: 9500 (nM), Ref: 25264584
Ki: 6000 (nM), Ref: 25264584
IC50: 1030 (nM), Ref: 25595683
IC50: 1170 (nM), Ref: 25600405
IC50: 3020 (nM), Ref: 25872983
IC50: 1000 (nM), Ref: 26083682
IC50: 1536 (nM), Ref: 26100442
IC50: 700 (nM), Ref: 26115570
IC50: 700 (nM), Ref: 26253631
IC50: 1536 (nM), Ref: 26481657
IC50: 730 (nM), Ref: 26711144
IC50: 3020 (nM), Ref: 26774579
IC50: 1536 (nM), Ref: 27123900
TCMC1786
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 4000 (nM), Ref: 21561086
Ki: 3560 (nM), Ref: 21561086
Ki: 660 (nM), Ref: 21561086
Ki: 940 (nM), Ref: 21561086
Ki: 160 (nM), Ref: 21561086
Ki: 72 (nM), Ref: 21561086
IC50: 90 (nM), Ref: 21561086
TCMC1786
TCMT190 T-cell protein-tyrosine phosphatase Homo sapiens IC50: 4230 (nM), Ref: 24684845
IC50: 4440 (nM), Ref: 25497963
IC50: 5460 (nM), Ref: 26100442
IC50: 5460 (nM), Ref: 26481657
IC50: 5460 (nM), Ref: 27123900
TCMC1786
TCMT563 Dual specificity phosphatase Cdc25B Homo sapiens IC50: 980 (nM), Ref: 25497963
TCMC662
TCMT683 Macrophage migration inhibitory factor Homo sapiens IC50: 250 (nM), Ref: 25743213
IC50: 1100 (nM), Ref: 25743213
TCMC876
TCMT560 Coagulation factor X Homo sapiens IC50: 720 (nM), Ref: 9834152
Ki: 450 (nM), Ref: 9834152
TCMC1609
TCMT44 Glyoxalase I Homo sapiens IC50: 560 (nM), Ref: 18258440
IC50: 560 (nM), Ref: 21669529
TCMC1609
TCMT156 Cytochrome P450 19A1 Homo sapiens IC50: 10000 (nM), Ref: 18778944
TCMC1609
TCMT737 DNA dC->dU-editing enzyme APOBEC-3G Homo sapiens IC50: 2390 (nM), Ref:
TCMC1609
TCMT739 G-protein coupled receptor 35 Homo sapiens IC50: 2120 (nM), Ref: 24900447
TCMC1609
TCMT558 DNA topoisomerase II alpha Homo sapiens IC50: 390 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC1609
TCMT207 Beta-secretase 1 Homo sapiens IC50: 2800 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1609
TCMT131 Acetylcholinesterase Homo sapiens IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1609
TCMT260 Tyrosine-protein kinase receptor FLT3 Homo sapiens IC50: 1690 (nM), Ref: 23411073
TCMC1609
TCMT2 Microtubule-associated protein tau Homo sapiens IC50: 1200 (nM), Ref: 23484434
IC50: 3000 (nM), Ref: 25086914
TCMC1609
TCMT8 Lysine-specific demethylase 4D-like Homo sapiens IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC1609
TCMT45 Beta amyloid A4 protein Homo sapiens IC50: 3000 (nM), Ref: 25086914
TCMC1609
TCMT740 PI3-kinase p110-gamma subunit Homo sapiens IC50: 4720 (nM), Ref: 25050878
TCMC1609
TCMT13 DNA-(apurinic or apyrimidinic site) lyase Homo sapiens IC50: 320 (nM), Ref: 25280182
TCMC1102
TCMT265 Glycogen synthase kinase-3 beta Homo sapiens IC50: 7500 (nM), Ref: 16610779
TCMC1102
TCMT752 Casein kinase II alpha Homo sapiens IC50: 40 (nM), Ref: 19414254
TCMC1102
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2320 (nM), Ref: 20185318
TCMC1102
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2180 (nM), Ref: 20185318
TCMC1102
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 9080 (nM), Ref: 20185318
TCMC1102
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7590 (nM), Ref: 20185318
TCMC1102
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7060 (nM), Ref: 20185318
TCMC1102
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6320 (nM), Ref: 20185318
Ki: 8790 (nM), Ref: 22892213
TCMC1102
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9370 (nM), Ref: 20185318
TCMC1102
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 8910 (nM), Ref: 20185318
TCMC1102
TCMT753 Mothers against decapentaplegic homolog 3 Homo sapiens IC50: 142 (nM), Ref:
TCMC1102
TCMT721 Heat shock 70 kDa protein 1 Homo sapiens IC50: 760 (nM), Ref:
TCMC1102
TCMT189 Dual specificity protein phosphatase 3 Homo sapiens IC50: 1230 (nM), Ref: IC50: 980 (nM), Ref:
TCMC1102
TCMT223 Aldose reductase Homo sapiens IC50: 200 (nM), Ref: 22261024
TCMC1102
TCMT479 Serine/threonine-protein kinase AKT Homo sapiens IC50: 3340 (nM), Ref: 22377675
TCMC1102
TCMT436 NUAK family SNF1-like kinase 1 Homo sapiens IC50: 510 (nM), Ref: 22377675
TCMC1102
TCMT354 Serine/threonine-protein kinase Aurora-A Homo sapiens IC50: 2480 (nM), Ref: 22377675
TCMC1102
TCMT374 Serine/threonine-protein kinase Aurora-B Homo sapiens IC50: 2500 (nM), Ref: 22377675
TCMC1102
TCMT626 Serine/threonine-protein kinase B-raf Homo sapiens IC50: 1760 (nM), Ref: 22377675
TCMC1102
TCMT423 Epidermal growth factor receptor erbB1 Homo sapiens IC50: 690 (nM), Ref: 22377675
TCMC1102
TCMT418 Ephrin type-B receptor 4 Homo sapiens IC50: 1830 (nM), Ref: 22377675
TCMC1102
TCMT704 Receptor protein-tyrosine kinase erbB-2 Homo sapiens IC50: 3540 (nM), Ref: 22377675
TCMC1102
TCMT441 Focal adhesion kinase 1 Homo sapiens IC50: 3110 (nM), Ref: 22377675
TCMC1102
TCMT369 Insulin-like growth factor I receptor Homo sapiens IC50: 250 (nM), Ref: 22377675
TCMC1102
TCMT212 Tyrosine-protein kinase SRC Homo sapiens IC50: 800 (nM), Ref: 22377675
TCMC1102
TCMT370 Vascular endothelial growth factor receptor 2 Homo sapiens IC50: 790 (nM), Ref: 22377675
TCMC1102
TCMT457 Vascular endothelial growth factor receptor 3 Homo sapiens IC50: 1540 (nM), Ref: 22377675
TCMC1102
TCMT377 Insulin receptor Homo sapiens IC50: 340 (nM), Ref: 22377675
TCMC1102
TCMT401 Hepatocyte growth factor receptor Homo sapiens IC50: 580 (nM), Ref: 22377675
TCMC1102
TCMT536 Platelet-derived growth factor receptor beta Homo sapiens IC50: 1300 (nM), Ref: 22377675
TCMC1102
TCMT484 Serine/threonine-protein kinase PLK1 Homo sapiens IC50: 3340 (nM), Ref: 22377675
TCMC1102
TCMT755 Serine/threonine-protein kinase PLK4 Homo sapiens IC50: 2970 (nM), Ref: 22377675
TCMC1102
TCMT502 Tyrosine-protein kinase TIE-2 Homo sapiens IC50: 260 (nM), Ref: 22377675
TCMC1102
TCMT756 Mitogen-activated protein kinase kinase kinase 8 Homo sapiens IC50: 2370 (nM), Ref: 22377675
TCMC1102
TCMT739 G-protein coupled receptor 35 Homo sapiens IC50: 100 (nM), Ref: 24900447
TCMC1102
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 8150 (nM), Ref: 22892213
TCMC1102
TCMT225 Carbonic anhydrase XIII Homo sapiens Ki: 4240 (nM), Ref: 22892213
TCMC1102
TCMT207 Beta-secretase 1 Homo sapiens IC50: 3900 (nM), Ref: 24835197
TCMC1982
TCMT239 Serine/threonine-protein kinase PIM1 Homo sapiens IC50: 43 (nM), Ref: 16302800
IC50: 500 (nM), Ref: 24328302
TCMC1982
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 790 (nM), Ref: 17378609
IC50: 4000 (nM), Ref: 24368208
TCMC1982
TCMT223 Aldose reductase Homo sapiens IC50: 2200 (nM), Ref: 18165015
IC50: 14.8 (nM), Ref: 18976928
IC50: 2200 (nM), Ref: 22261024
IC50: 2900 (nM), Ref: 25152999
TCMC1982
TCMT44 Glyoxalase I Homo sapiens IC50: 3200 (nM), Ref: 18258440
TCMC1982
TCMT66 Estradiol 17-beta-dehydrogenase 2 Homo sapiens IC50: 1540 (nM), Ref: 18533708
TCMC1982
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 7890 (nM), Ref: 20185318
TCMC1982
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 8100 (nM), Ref: 20185318
TCMC1982
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2540 (nM), Ref: 20185318
TCMC1982
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2680 (nM), Ref: 20185318
TCMC1982
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 6810 (nM), Ref: 20185318
TCMC1982
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 6170 (nM), Ref: 20185318
TCMC1982
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 4840 (nM), Ref: 20185318
TCMC1982
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 7000 (nM), Ref: 20185318
TCMC1982
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9390 (nM), Ref: 20185318
TCMC1982
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 5410 (nM), Ref: 20185318
TCMC1158
TCMT207 Beta-secretase 1 Homo sapiens IC50: 3100 (nM), Ref: 24835197
Ki: 6840 (nM), Ref: 24835197
TCMC1982
TCMT156 Cytochrome P450 19A1 Homo sapiens IC50: 12 (nM), Ref: 20413308
TCMC1982
TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 4097 (nM), Ref: 20696580
IC50: 1550 (nM), Ref: 22328583
TCMC1982
TCMT215 Cytochrome P450 1A1 Homo sapiens IC50: 1191 (nM), Ref: 20696580
TCMC1982
TCMT257 Cytochrome P450 1B1 Homo sapiens IC50: 77 (nM), Ref: 20696580
TCMC1982
TCMT306 Matrix metalloproteinase-2 Homo sapiens IC50: 6680 (nM), Ref: 22658537
TCMC1982
TCMT320 Matrix metalloproteinase 3 Homo sapiens IC50: 5570 (nM), Ref: 22658537
TCMC1982
TCMT321 Matrix metalloproteinase 9 Homo sapiens IC50: 1610 (nM), Ref: 22658537
TCMC1982
TCMT322 Matrix metalloproteinase 13 Homo sapiens IC50: 8460 (nM), Ref: 22658537
TCMC1982
TCMT422 CaM kinase II beta Homo sapiens IC50: 3000 (nM), Ref: 21798748
TCMC1982
TCMT265 Glycogen synthase kinase-3 beta Homo sapiens IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982
TCMT207 Beta-secretase 1 Homo sapiens IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y
IC50: 6500 (nM), Ref: 26003344
TCMC1982
TCMT784 Vasopressin V2 receptor Homo sapiens IC50: 7000 (nM), Ref: 23437772
IC50: 6309.57 (nM), Ref: 23437772
TCMC1982
TCMT785 Interleukin-8 receptor A Homo sapiens IC50: 4500 (nM), Ref: 23437772
IC50: 5011.87 (nM), Ref: 23437772
TCMC1982
TCMT786 C-C chemokine receptor type 4 Homo sapiens IC50: 10000 (nM), Ref: 23437772
TCMC1982
TCMT260 Tyrosine-protein kinase receptor FLT3 Homo sapiens IC50: 590 (nM), Ref: 23411073
TCMC1982
TCMT601 Thrombin Homo sapiens IC50: 1500 (nM), Ref: 24610996
TCMC1982
TCMT370 Vascular endothelial growth factor receptor 2 Homo sapiens IC50: 280 (nM), Ref: 24328302
TCMC1982
TCMT212 Tyrosine-protein kinase SRC Homo sapiens IC50: 120 (nM), Ref: 24328302
TCMC1982
TCMT791 Protein kinase N1 Homo sapiens IC50: 5800 (nM), Ref: 24328302
TCMC1982
TCMT484 Serine/threonine-protein kinase PLK1 Homo sapiens IC50: 5750 (nM), Ref: 24328302
TCMC1982
TCMT462 Serine/threonine-protein kinase NEK6 Homo sapiens IC50: 4230 (nM), Ref: 24328302
TCMC1982
TCMT445 Serine/threonine-protein kinase NEK2 Homo sapiens IC50: 5730 (nM), Ref: 24328302
TCMC1982
TCMT401 Hepatocyte growth factor receptor Homo sapiens IC50: 580 (nM), Ref: 24328302
TCMC1982
TCMT369 Insulin-like growth factor I receptor Homo sapiens IC50: 300 (nM), Ref: 24328302
TCMC1982
TCMT441 Focal adhesion kinase 1 Homo sapiens IC50: 1200 (nM), Ref: 24328302
TCMC1982
TCMT388 Tyrosine-protein kinase receptor UFO Homo sapiens IC50: 960 (nM), Ref: 24328302
TCMC1982
TCMT374 Serine/threonine-protein kinase Aurora-B Homo sapiens IC50: 910 (nM), Ref: 24328302
TCMC1982
TCMT436 NUAK family SNF1-like kinase 1 Homo sapiens IC50: 5090 (nM), Ref: 24328302
TCMC1982
TCMT402 ALK tyrosine kinase receptor Homo sapiens IC50: 3320 (nM), Ref: 24328302
TCMC1982
TCMT479 Serine/threonine-protein kinase AKT Homo sapiens IC50: 5390 (nM), Ref: 24328302
TCMC1982
TCMT592 Xanthine dehydrogenase Homo sapiens Ki: 280 (nM), Ref: 25060641
IC50: 3500 (nM), Ref: 27162124
TCMC1982
TCMT793 Liver glycogen phosphorylase Homo sapiens IC50: 4800 (nM), Ref: 25092521
TCMC1982
TCMT33 Cytochrome P450 3A4 Homo sapiens IC50: 2110 (nM), Ref: 22328583
TCMC1982
TCMT217 Cytochrome P450 2C8 Homo sapiens IC50: 1390 (nM), Ref: 22328583
TCMC1982
TCMT261 Death-associated protein kinase 1 Homo sapiens IC50: 8900 (nM), Ref: 26322379
TCMC2105
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1202
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 7030 (nM), Ref: 20185318
TCMC1202
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 7780 (nM), Ref: 20185318
TCMC1202
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 6990 (nM), Ref: 20185318
TCMC1202
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6070 (nM), Ref: 20185318
TCMC1202
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 6130 (nM), Ref: 20185318
TCMC1202
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9970 (nM), Ref: 20185318
TCMC1202
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 4080 (nM), Ref: 20185318
TCMC1202
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 9800 (nM), Ref: 20185318
TCMC1202
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 7490 (nM), Ref: 20185318
TCMC1202
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2250 (nM), Ref: 20185318
TCMC1202
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3200 (nM), Ref: 20185318
TCMC1202
TCMT822 Alpha-(1,3)-fucosyltransferase 7 Homo sapiens IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC2139
TCMT560 Coagulation factor X Homo sapiens IC50: 210 (nM), Ref: 9834152
Ki: 440 (nM), Ref: 9834152
TCMC1788
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT126 Telomerase reverse transcriptase Homo sapiens IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788
TCMT297 Fatty acid binding protein adipocyte Homo sapiens Ki: 1500 (nM), Ref: 27460668
TCMC847
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 8710 (nM), Ref: 20185318
Ki: 8710 (nM), Ref: 26498394
TCMC847
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9060 (nM), Ref: 20185318
Ki: 9060 (nM), Ref: 26498394
TCMC847
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 7870 (nM), Ref: 20185318
TCMC847
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6420 (nM), Ref: 20185318
TCMC847
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7330 (nM), Ref: 20185318
TCMC847
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9080 (nM), Ref: 20185318
TCMC847
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 6490 (nM), Ref: 20185318
TCMC847
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 10000 (nM), Ref: 20185318
TCMC847
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 1610 (nM), Ref: 20185318
TCMC847
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2380 (nM), Ref: 20185318
TCMC847
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 3060 (nM), Ref: 19476336
TCMC847
TCMT321 Matrix metalloproteinase 9 Homo sapiens IC50: 21.22 (nM), Ref: 23375794
IC50: 10 (nM), Ref: 23375794
TCMC847
TCMT306 Matrix metalloproteinase-2 Homo sapiens IC50: 24.26 (nM), Ref: 23375794
TCMC847
TCMT295 Matrix metalloproteinase-1 Homo sapiens IC50: 238.91 (nM), Ref: 23375794
TCMC847
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 8500 (nM), Ref: 26197161
TCMC2216
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 3600 (nM), Ref: 17489632
IC50: 3100 (nM), Ref: 18798681
IC50: 3600 (nM), Ref: 19008110
IC50: 3600 (nM), Ref: 17125223
IC50: 3800 (nM), Ref: 19846295
IC50: 3900 (nM), Ref: 19632832
IC50: 3600 (nM), Ref: 19836230
IC50: 3100 (nM), Ref: 21555221
IC50: 3600 (nM), Ref: 21571537
IC50: 3100 (nM), Ref: 22940448
IC50: 2300 (nM), Ref: 21453996
Ki: 3400 (nM), Ref: 21453996
IC50: 3600 (nM), Ref: 23022281
IC50: 3080 (nM), Ref: 23141910
IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 2750 (nM), Ref: 23387824
IC50: 4120 (nM), Ref: 24224843
IC50: 4000 (nM), Ref: 24953600
IC50: 3500 (nM), Ref: 25559759
IC50: 3400 (nM), Ref: 25907369
Ki: 6400 (nM), Ref: 25907369
IC50: 5200 (nM), Ref: 26841168
TCMC2216
TCMT174 11-beta-hydroxysteroid dehydrogenase 1 Homo sapiens IC50: 1900 (nM), Ref: 20100662
TCMC2216
TCMT102 Low molecular weight phosphotyrosine protein phosphatase Homo sapiens IC50: 7200 (nM), Ref: 21453996
TCMC2216
TCMT103 Receptor-type tyrosine-protein phosphatase F (LAR) Homo sapiens IC50: 3800 (nM), Ref: 21453996
TCMC2216
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens Ki: 6000 (nM), Ref: 21561086
Ki: 3700 (nM), Ref: 21561086
Ki: 2100 (nM), Ref: 21561086
Ki: 2800 (nM), Ref: 21561086
Ki: 2000 (nM), Ref: 21561086
IC50: 4000 (nM), Ref: 21561086
TCMC2216
TCMT190 T-cell protein-tyrosine phosphatase Homo sapiens IC50: 2400 (nM), Ref: 23387824
TCMC2216
TCMT150 Nuclear receptor ROR-gamma Homo sapiens IC50: 680 (nM), Ref: 10.1039/C3MD00005B
IC50: 130 (nM), Ref: 24704616
IC50: 1060 (nM), Ref: 24704616
IC50: 9410 (nM), Ref: 24704616

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1429
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 16.77 (ug/ml), Ref: 20116898
TCMC1786
TCMT1107 Protease Human immunodeficiency virus 1 IC50: 10 (ug/ml), Ref: 10691716
TCMC2257
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 15.46 (ug/ml), Ref: 20116898
TCMC1609
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 26.29 (ug/ml), Ref: 20116898
TCMC1982
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 17.65 (ug/ml), Ref: 20116898
TCMC2324
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC2013
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 50 (ug/ml), Ref: 12762812
TCMC2366
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 2.8 (ug/ml), Ref: 17845001
TCMC1429
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 7.93 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2417
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 16 (ug/ml), Ref: 25760525
MIC: 32 (ug/ml), Ref: 25760525
TCMC2417
TCMT1187 Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC: 16 (ug/ml), Ref: 25760525
TCMC2417
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 16 (ug/ml), Ref: 25760525
TCMC2417
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 8 (ug/ml), Ref: 25760525
TCMC1786
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 50 (ug/ml), Ref: 11141098
MIC: 100 (ug/ml), Ref: 18798682
MIC: 64 (ug/ml), Ref: 15387646
MIC: 29 (ug/ml), Ref: 23356207
TCMC1786
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 21.8 (ug/ml), Ref: 9748372
TCMC1786
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 16 (ug/ml), Ref: 21288041
TCMC1786
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 50 (ug/ml), Ref: 11141098
MIC: 100 (ug/ml), Ref: 18798682
MIC: 64 (ug/ml), Ref: 15387646
MIC: 29 (ug/ml), Ref: 23356207
TCMC2257
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 15.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
MIC: 37.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
MIC: 59.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1609
TCMT1246 Escherichia coli Escherichia coli MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
IC50: 0.88 (ug/ml), Ref: 24749980
TCMC1609
TCMT1412 Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1609
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1609
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1102
TCMT1246 Escherichia coli Escherichia coli MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102
TCMT1412 Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.103 (ug/ml), Ref: 11374952
IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 0.103 (ug/ml), Ref: 11374952
IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans IC50: 5.5 (ug/ml), Ref: 12502337
TCMC1982
TCMT1246 Escherichia coli Escherichia coli MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982
TCMT1412 Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 50 (ug/ml), Ref: 12762812
MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982
TCMT1286 Bacillus cereus Bacillus cereus MIC: 50 (ug/ml), Ref: 12762812
TCMC1982
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982
TCMT1442 Leishmania donovani Leishmania donovani IC50: 29.5 (ug/ml), Ref: 12398543
IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982
TCMT1208 Escherichia coli K12 Escherichia coli K-12 MIC: 64 (ug/ml), Ref: 20655215
MIC: 64 (ug/ml), Ref: 21534606
TCMC1982
TCMT1212 Verticillium dahliae Verticillium dahliae IC50: 6 (ug/ml), Ref: 17394331
TCMC1982
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC2534
TCMT1251 Candida albicans Candida albicans MIC: 64 (ug/ml), Ref: 22424614
TCMC1202
TCMT1178 Actinomyces viscosus Actinomyces viscosus MIC: 78 (ug/ml), Ref: 8904847
TCMC1202
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 14.8 (ug/ml), Ref: 15844943
TCMC2578
TCMT1251 Candida albicans Candida albicans IC50: 82.98 (ug/ml), Ref: 25686593
TCMC915
TCMT1246 Escherichia coli Escherichia coli MIC: 1 (ug/ml), Ref: 25791674
TCMC915
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2166
TCMT1211 Fusobacterium nucleatum Fusobacterium nucleatum MIC: 50 (ug/ml), Ref: 8864235
TCMC2166
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1321 Staphylococcus hominis Staphylococcus hominis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1209 Staphylococcus haemolyticus Staphylococcus haemolyticus MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1343 Staphylococcus simulans Staphylococcus simulans MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1344 Staphylococcus sciuri Staphylococcus sciuri MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1251 Candida albicans Candida albicans MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1246 Escherichia coli Escherichia coli MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC1788
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 24103427
TCMC2216
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 6.5 (ug/ml), Ref: 9748372
TCMC2216
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 32 (ug/ml), Ref: 15387646
MIC: 100 (ug/ml), Ref: 20542692
TCMC2216
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 16 (ug/ml), Ref: 21288041
TCMC2815
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 50 (ug/ml), Ref: 1517735
TCMC2822
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 6.25 (ug/ml), Ref: 17845001
TCMC1982
TCMT1093 Enoyl-acyl-carrier protein reductase Plasmodium falciparum Ki: 22 (nM), Ref: 17263522