Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
.
| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
 |
TCMT101 | Protein-tyrosine phosphatase 1B | Homo sapiens |
IC50: 3900 (nM), Ref: 16580200 IC50: 7600 (nM), Ref: 18798681 IC50: 4200 (nM), Ref: 19702283 IC50: 3840 (nM), Ref: 22044245 IC50: 5600 (nM), Ref: 22690646 IC50: 9500 (nM), Ref: 21453996 Ki: 6000 (nM), Ref: 21453996 IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2600 (nM), Ref: 23357636 IC50: 1100 (nM), Ref: 23434422 IC50: 3020 (nM), Ref: 23942421 IC50: 2010 (nM), Ref: 24090912 IC50: 1900 (nM), Ref: 24684845 IC50: 3020 (nM), Ref: 25497963 IC50: 9500 (nM), Ref: 25264584 Ki: 6000 (nM), Ref: 25264584 IC50: 1030 (nM), Ref: 25595683 IC50: 1170 (nM), Ref: 25600405 IC50: 3020 (nM), Ref: 25872983 IC50: 1000 (nM), Ref: 26083682 IC50: 1536 (nM), Ref: 26100442 IC50: 700 (nM), Ref: 26115570 IC50: 700 (nM), Ref: 26253631 IC50: 1536 (nM), Ref: 26481657 IC50: 730 (nM), Ref: 26711144 IC50: 3020 (nM), Ref: 26774579 IC50: 1536 (nM), Ref: 27123900 |
|
|
TCMT280 | Aldo-keto reductase family 1 member B10 | Homo sapiens |
IC50: 4000 (nM), Ref: 21561086 Ki: 3560 (nM), Ref: 21561086 Ki: 660 (nM), Ref: 21561086 Ki: 940 (nM), Ref: 21561086 Ki: 160 (nM), Ref: 21561086 Ki: 72 (nM), Ref: 21561086 IC50: 90 (nM), Ref: 21561086 |
|
|
TCMT190 | T-cell protein-tyrosine phosphatase | Homo sapiens |
IC50: 4230 (nM), Ref: 24684845 IC50: 4440 (nM), Ref: 25497963 IC50: 5460 (nM), Ref: 26100442 IC50: 5460 (nM), Ref: 26481657 IC50: 5460 (nM), Ref: 27123900 |
|
|
TCMT563 | Dual specificity phosphatase Cdc25B | Homo sapiens |
IC50: 980 (nM), Ref: 25497963 |
 |
TCMT239 | Serine/threonine-protein kinase PIM1 | Homo sapiens |
IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302 |
|
|
TCMT130 | Arachidonate 5-lipoxygenase | Homo sapiens |
IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208 |
|
|
TCMT223 | Aldose reductase | Homo sapiens |
IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999 |
|
|
TCMT44 | Glyoxalase I | Homo sapiens |
IC50: 3200 (nM), Ref: 18258440 |
|
|
TCMT66 | Estradiol 17-beta-dehydrogenase 2 | Homo sapiens |
IC50: 1540 (nM), Ref: 18533708 |
|
|
TCMT142 | Carbonic anhydrase IV | Homo sapiens |
Ki: 7890 (nM), Ref: 20185318 |
Showing 1 to 10 of 65 entries