Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC1399	TCMT223	Aldose reductase	Homo sapiens	IC50: 320 (nM), Ref: 22261024
TCMC1361	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 160 (nM), Ref: 18778098
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC829	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 8100 (nM), Ref: 20493686
TCMC829	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 1800 (nM), Ref: 20493686
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1105	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 2000 (nM), Ref: 19414254
TCMC1105	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2500 (nM), Ref: 27173800
TCMC1008	TCMT186	Monoamine oxidase B	Homo sapiens	IC50: 8.61 (nM), Ref: 21405131 IC50: 8709.64 (nM), Ref: 24169316
TCMC1742	TCMT637	NAD-dependent deacetylase sirtuin 3	Homo sapiens	IC50: 6200 (nM), Ref: 25275824
TCMC1742	TCMT638	NAD-dependent deacetylase sirtuin 2	Homo sapiens	IC50: 6300 (nM), Ref: 25549554 IC50: 1200 (nM), Ref: 26696402

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1399	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1136	Neuraminidase	Influenza A virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1121	Sialidase	Clostridium perfringens	IC50: 11.28 (ug/ml), Ref: 21123068
TCMC2288	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 55 (ug/ml), Ref: 20116898
TCMC2332	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 13 (ug/ml), Ref: 16392829
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2415	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14 (ug/ml), Ref: 16392829
TCMC1399	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 62.5 (ug/ml), Ref: 18951808
TCMC1399	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.6 (ug/ml), Ref: 25137491
TCMC1767	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 60 (ug/ml), Ref: 20384293
TCMC1767	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC2548	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 20 (ug/ml), Ref: 16392829
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2593	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 17601740
TCMC1105	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 23534483
TCMC1105	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1 (ug/ml), Ref: 23534483
TCMC1105	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 23534483 MIC: 4 (ug/ml), Ref: 23534483