TCM Putative Target References: TCMH2580


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1173
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9430 (nM), Ref: 20185318
Ki: 9430 (nM), Ref: 26498394
TCMC1173
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9780 (nM), Ref: 20185318
Ki: 9780 (nM), Ref: 26498394
TCMC1173
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9870 (nM), Ref: 20185318
TCMC1173
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7410 (nM), Ref: 20185318
TCMC1173
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 8450 (nM), Ref: 20185318
TCMC1173
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7040 (nM), Ref: 20185318
TCMC1173
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2400 (nM), Ref: 20185318
TCMC1173
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2890 (nM), Ref: 20185318
TCMC2013
TCMT223 Aldose reductase Homo sapiens IC50: 2700 (nM), Ref: 22261024
TCMC2188
TCMT223 Aldose reductase Homo sapiens IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1424
TCMT33 Cytochrome P450 3A4 Homo sapiens IC50: 2100 (nM), Ref: 17994701
TCMC315
TCMT46 Coagulation factor III Homo sapiens IC50: 14.98 (nM), Ref: 23199480
TCMC2150
TCMT46 Coagulation factor III Homo sapiens IC50: 22.78 (nM), Ref: 23199480
TCMC2150
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 231 (nM), Ref: 23332346
TCMC785
TCMT131 Acetylcholinesterase Homo sapiens IC50: 610 (nM), Ref: 23062825
TCMC897
TCMT223 Aldose reductase Homo sapiens IC50: 300 (nM), Ref: 22236472
IC50: 1800 (nM), Ref: 22261024
TCMC897
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 7900 (nM), Ref: 22236472
TCMC1828
TCMT33 Cytochrome P450 3A4 Homo sapiens IC50: 900 (nM), Ref: 17994701
TCMC784
TCMT131 Acetylcholinesterase Homo sapiens IC50: 100 (nM), Ref: 26003344
TCMC784
TCMT132 Butyrylcholinesterase Homo sapiens IC50: 1090 (nM), Ref: 26003344

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1425
TCMT1109 Reverse transcriptase Human immunodeficiency virus 1 IC50: 71 (ug/ml), Ref: 1710653
IC50: 71 (ug/ml), Ref: 21295891
TCMC785
TCMT1104 Sortase Staphylococcus aureus IC50: 8.7 (ug/ml), Ref: 17716892
IC50: 8.7 (ug/ml), Ref: 19269184
TCMC785
TCMT1109 Reverse transcriptase Human immunodeficiency virus 1 IC50: 100 (ug/ml), Ref: 1710653
IC50: 100 (ug/ml), Ref: 21295891
TCMC785
TCMT1154 Sortase Staphylococcus aureus IC50: 40.6 (ug/ml), Ref: 26551342
TCMC1491
TCMT1109 Reverse transcriptase Human immunodeficiency virus 1 IC50: 0.00423 (ug/ml), Ref: 21334901
IC50: 0.00211 (ug/ml), Ref: 21334901
TCMC2013
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 50 (ug/ml), Ref: 12762812
TCMC2383
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2398
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.557 (ug/ml), Ref: 3286870
IC50: 2.008 (ug/ml), Ref: 3286870
TCMC1424
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2237
TCMT1464 Hepatitis B virus Hepatitis B virus IC50: 4 (ug/ml), Ref: 24549242
TCMC2506
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 1.99 (ug/ml), Ref: 8786363
IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 1.99 (ug/ml), Ref: 8786363
IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1425
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.422 (ug/ml), Ref: 3286870
IC50: 1.607 (ug/ml), Ref: 3286870
TCMC934
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC801
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 32 (ug/ml), Ref: 15844943
TCMC801
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC785
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.36 (ug/ml), Ref: 10.1016/S0960-894X(00)80357-1
IC50: 0.141 (ug/ml), Ref: 3286870
IC50: 0.148 (ug/ml), Ref: 3286870
TCMC785
TCMT1246 Escherichia coli Escherichia coli MIC: 5 (ug/ml), Ref: 16359864
MIC: 31.25 (ug/ml), Ref: 18591276
TCMC785
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans MIC: 64 (ug/ml), Ref: 16730982
MIC: 31.3 (ug/ml), Ref: 16872133
TCMC785
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 100 (ug/ml), Ref: 17716892
MIC: 50 (ug/ml), Ref: 9784149
MIC: 60 (ug/ml), Ref: 15568768
MBC: 64 (ug/ml), Ref: 10.1007/s00044-013-0844-5
MIC: 32 (ug/ml), Ref: 10.1007/s00044-013-0844-5
TCMC785
TCMT1226 Klebsiella pneumoniae Klebsiella pneumoniae MIC: 100 (ug/ml), Ref: 9784149
TCMC785
TCMT1439 Mycobacterium smegmatis Mycobacterium smegmatis MIC: 25 (ug/ml), Ref: 9784149
TCMC785
TCMT1251 Candida albicans Candida albicans MIC: 100 (ug/ml), Ref: 9784149
MIC: 31.3 (ug/ml), Ref: 16872133
MIC: 15.6 (ug/ml), Ref: 16872133
TCMC785
TCMT1385 Candida shehatae Candida shehatae MIC: 7.8 (ug/ml), Ref: 16872133
TCMC897
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1491
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 0.92 (ug/ml), Ref: 21334901
TCMC1491
TCMT1318 Human T-lymphotropic virus 1 Human T-lymphotropic virus 1 IC50: 1.07 (ug/ml), Ref: 21334901
TCMC1828
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.281 (ug/ml), Ref: 3286870
IC50: 0.163 (ug/ml), Ref: 3286870
TCMC784
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2811
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 37.35 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1047
TCMT1464 Hepatitis B virus Hepatitis B virus IC50: 50 (nM), Ref: 24549242