Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1922	TCMT634	Norepinephrine transporter	Homo sapiens	IC50: 6040 (nM), Ref: 17573162
TCMC2180	TCMT302	HMG-CoA reductase	Homo sapiens	IC50: 5860 (nM), Ref: 25311563 IC50: 36.31 (nM), Ref: 25311563

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2264	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 13.01 (ug/ml), Ref: 22552195 IC50: 11.54 (ug/ml), Ref: 22552195 IC50: 22.45 (ug/ml), Ref: 22552195 IC50: 23.54 (ug/ml), Ref: 22552195
TCMC2264	TCMT1136	Neuraminidase	Influenza A virus	IC50: 13.01 (ug/ml), Ref: 22552195 IC50: 11.54 (ug/ml), Ref: 22552195 IC50: 22.45 (ug/ml), Ref: 22552195 IC50: 23.54 (ug/ml), Ref: 22552195
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC2305	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 12.8 (ug/ml), Ref: 22552195 IC50: 9.33 (ug/ml), Ref: 22552195 IC50: 25.59 (ug/ml), Ref: 22552195 IC50: 28.42 (ug/ml), Ref: 22552195
TCMC2305	TCMT1136	Neuraminidase	Influenza A virus	IC50: 12.8 (ug/ml), Ref: 22552195 IC50: 9.33 (ug/ml), Ref: 22552195 IC50: 25.59 (ug/ml), Ref: 22552195 IC50: 28.42 (ug/ml), Ref: 22552195
TCMC2363	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 22537683
TCMC2404	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 18710283 MIC: 28 (ug/ml), Ref: 22280816
TCMC2404	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 100 (ug/ml), Ref: 18710283 MIC: 28 (ug/ml), Ref: 22280816
TCMC2481	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC2481	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268
TCMC2481	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 50 (ug/ml), Ref: 17027268
TCMC2481	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268
TCMC2481	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 17027268
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC319	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 46.9 (ug/ml), Ref: 22014830
TCMC319	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 22014830
TCMC319	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 31.3 (ug/ml), Ref: 22014830
TCMC319	TCMT1251	Candida albicans	Candida albicans	MIC: 31.3 (ug/ml), Ref: 22014830
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1578	TCMT1408	Colletotrichum gloeosporioides	Colletotrichum gloeosporioides	IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578	TCMT1245	Phytophthora cactorum	Phytophthora cactorum	IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC2688	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 14969530
TCMC2688	TCMT1282	Colletotrichum orbiculare	Colletotrichum orbiculare	MIC: 30 (ug/ml), Ref: 14969530