Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC910	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1118 (nM), Ref: 20696580
TCMC910	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 95 (nM), Ref: 20696580
TCMC910	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 20 (nM), Ref: 20696580
TCMC614	TCMT151	Protein kinase C alpha	Homo sapiens	IC50: 9300 (nM), Ref: 9834166
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC710	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554
TCMC710	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 710 (nM), Ref: 18533708
TCMC710	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 800 (nM), Ref: 19414254
TCMC710	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5200 (nM), Ref: 19592245
TCMC710	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 795 (nM), Ref: 20696580
TCMC710	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 427 (nM), Ref: 20696580
TCMC710	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC710	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1450 (nM), Ref: 23411073
TCMC710	TCMT128	Tankyrase-2	Homo sapiens	IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272
TCMC710	TCMT129	Tankyrase-1	Homo sapiens	IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272
TCMC710	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844
TCMC710	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC710	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 8.54 (ug/ml), Ref: 20116898
TCMC614	TCMT1454	Bacillus subtilis	Bacillus subtilis	IC50: 98.5 (ug/ml), Ref: 25981688
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1246	Escherichia coli	Escherichia coli	MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC710	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC710	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K