Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC338	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 2490 (nM), Ref: IC50: 3540 (nM), Ref:
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC1582	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 4100 (nM), Ref: 22668600
TCMC1582	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 820 (nM), Ref: 22668600
TCMC1582	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5500 (nM), Ref: 22668600
TCMC1582	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 780 (nM), Ref: 22668600
TCMC1582	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3400 (nM), Ref: 22668600
TCMC1582	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2600 (nM), Ref: 22668600
TCMC1748	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 85 (nM), Ref: 16562853 Ki: 314 (nM), Ref: 25695425
TCMC1748	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 373 (nM), Ref: 25695425
TCMC1748	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 20 (nM), Ref: 25695425
TCMC1748	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 306 (nM), Ref: 25695425
TCMC1748	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 566 (nM), Ref: 25695425
TCMC1748	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 323 (nM), Ref: 25695425
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC6	TCMT46	Coagulation factor III	Homo sapiens	IC50: 152.43 (nM), Ref: 23199480
TCMC6	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 50 (nM), Ref: 23332346
TCMC6	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 305 (nM), Ref: 23332346
TCMC6	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 149 (nM), Ref: 23332346
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC1556	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3840 (nM), Ref: 21402476
TCMC1556	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3530 (nM), Ref: 21402476
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1566	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 830 (nM), Ref: 22668600
TCMC1566	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 810 (nM), Ref: 22668600
TCMC1566	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 850 (nM), Ref: 22668600
TCMC1566	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 820 (nM), Ref: 22668600
TCMC1566	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 800 (nM), Ref: 22668600
TCMC1566	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 780 (nM), Ref: 22668600
TCMC848	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 7.28 (nM), Ref: 23375794
TCMC848	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 8.2 (nM), Ref: 23375794
TCMC848	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 3301.33 (nM), Ref: 23375794
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC2209	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 3400 (nM), Ref: 23388705 IC50: 5400 (nM), Ref: 23388705
TCMC2209	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 5200 (nM), Ref: 23388705 IC50: 5800 (nM), Ref: 23388705

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC2317	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 3.9 (ug/ml), Ref: 8786363 IC50: 2.53 (ug/ml), Ref: 8786363
TCMC2317	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 3.9 (ug/ml), Ref: 8786363 IC50: 2.53 (ug/ml), Ref: 8786363
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC1582	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.25 (ug/ml), Ref: 18539361
TCMC1582	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 12.5 (ug/ml), Ref: 18539361
TCMC1582	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 25 (ug/ml), Ref: 18539361
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC2458	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 20542692
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2528	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC2543	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 1.6 (ug/ml), Ref: 20384293
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2642	TCMT1251	Candida albicans	Candida albicans	IC50: 3.5 (ug/ml), Ref: 12088427 MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 12088427 IC50: 2 (ug/ml), Ref: 12088427
TCMC2642	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 2 (ug/ml), Ref: 12088427 MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642	TCMT1355	Rhodococcus equi	Rhodococcus equi	MIC: 10 (ug/ml), Ref: 19639965
TCMC2642	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 12 (ug/ml), Ref: 19874044
TCMC2642	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC2642	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 12.5 (ug/ml), Ref: 22280816