Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC1207	TCMT718	Thioredoxin, mitochondrial	Homo sapiens	Ki: 1310 (nM), Ref: 22663155
TCMC1207	TCMT719	Thioredoxin	Homo sapiens	Ki: 3110 (nM), Ref: 22663155
TCMC1207	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 790 (nM), Ref: 10.1039/C5MD00582E
TCMC1597	TCMT807	Solute carrier family 22 member 12	Homo sapiens	IC50: 2000 (nM), Ref: 17325024 Ki: 5740 (nM), Ref: 17325024
TCMC1597	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2927.18 (nM), Ref:
TCMC1597	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 2988.26 (nM), Ref:
TCMC1597	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 1600 (nM), Ref: 24900447
TCMC1597	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 1600 (nM), Ref: 26322379
TCMC1597	TCMT283	Receptor-type tyrosine-protein phosphatase S	Homo sapiens	IC50: 4300 (nM), Ref: 26602279
TCMC1534	TCMT81	Arachidonate 12-lipoxygenase	Homo sapiens	IC50: 580 (nM), Ref: 17826100
TCMC1534	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	IC50: 3100 (nM), Ref: 17826100
TCMC1534	TCMT41	Isocitrate dehydrogenase [NADP] cytoplasmic	Homo sapiens	Ki: 2850 (nM), Ref: 26508549
TCMC1228	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 5200 (nM), Ref: 18558747

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1229	TCMT1190	Plasmodium falciparum (isolate FcB1 / Columbia)	Plasmodium falciparum FcB1/Columbia	IC50: 2.8 (ug/ml), Ref: 19296616
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1232	TCMT1190	Plasmodium falciparum (isolate FcB1 / Columbia)	Plasmodium falciparum FcB1/Columbia	IC50: 3.1 (ug/ml), Ref: 19296616
TCMC1232	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 19604701
TCMC1534	TCMT1190	Plasmodium falciparum (isolate FcB1 / Columbia)	Plasmodium falciparum FcB1/Columbia	IC50: 2.9 (ug/ml), Ref: 19296616
TCMC1534	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 19604701 MIC: 2 (ug/ml), Ref: 25474410 MIC: 64 (ug/ml), Ref: 25651042 MIC: 2 (ug/ml), Ref: 26681070
TCMC1534	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 15.24 (ug/ml), Ref: 22280816
TCMC1534	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 2 (ug/ml), Ref: 25474410 MIC: 8 (ug/ml), Ref: 25651042
TCMC1534	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 25651042
TCMC1534	TCMT1246	Escherichia coli	Escherichia coli	MIC: 64 (ug/ml), Ref: 25651042
TCMC1534	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 64 (ug/ml), Ref: 25651042
TCMC1533	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 4 (ug/ml), Ref: 25651042
TCMC1533	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 25651042
TCMC1533	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 25651042