TCM Putative Target References: TCMH1442


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2051
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 8710 (nM), Ref: 22892213
TCMC2051
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4050 (nM), Ref: 22892213
TCMC2051
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 960 (nM), Ref: 22892213
TCMC1107
TCMT290 Muscarinic acetylcholine receptor M5 Homo sapiens Ki: 0.14 (nM), Ref: 23707254
Ki: 0.3388 (nM), Ref: 24365159
Ki: 0.34 (nM), Ref: 24365159
Ki: 3.02 (nM), Ref: 25051097
TCMC1107
TCMT291 Muscarinic acetylcholine receptor M3 Homo sapiens Ki: 0.2692 (nM), Ref: 24365159
Ki: 0.27 (nM), Ref: 24365159
TCMC1107
TCMT292 Muscarinic acetylcholine receptor M1 Homo sapiens Ki: 0.2692 (nM), Ref: 24365159
Ki: 0.27 (nM), Ref: 24365159
TCMC1107
TCMT293 Muscarinic acetylcholine receptor M2 Homo sapiens Ki: 5.012 (nM), Ref: 25051097
Ki: 12.88 (nM), Ref: 25051097
Ki: 3.631 (nM), Ref: 25051097
Ki: 2.818 (nM), Ref: 25051097
TCMC2204
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 482 (nM), Ref: 21067924
Ki: 478 (nM), Ref: 22077347
Ki: 480 (nM), Ref: 26688270
TCMC2204
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 754 (nM), Ref: 22077347
Ki: 750 (nM), Ref: 26688270
TCMC2201
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 8700 (nM), Ref: 21332115
TCMC746
TCMT291 Muscarinic acetylcholine receptor M3 Homo sapiens Ki: 0.5 (nM), Ref: 11831911
Ki: 0.9 (nM), Ref: 20684563
Ki: 2.18 (nM), Ref: 23523385
TCMC746
TCMT292 Muscarinic acetylcholine receptor M1 Homo sapiens Ki: 0.25 (nM), Ref: 11831911
Ki: 1.202 (nM), Ref: 22329602
Ki: 0.5754 (nM), Ref: 22329602
Ki: 0.922 (nM), Ref: 23523385
TCMC746
TCMT293 Muscarinic acetylcholine receptor M2 Homo sapiens Ki: 1.5 (nM), Ref: 11831911
Ki: 1.9 (nM), Ref: 20684563
Ki: 1.44 (nM), Ref: 23523385
TCMC746
TCMT551 Muscarinic acetylcholine receptor M4 Homo sapiens Ki: 0.34 (nM), Ref: 11831911
Ki: 3 (nM), Ref: 20684563
Ki: 1.39 (nM), Ref: 23523385
TCMC746
TCMT290 Muscarinic acetylcholine receptor M5 Homo sapiens Ki: 0.54 (nM), Ref: 11831911
Ki: 0.21 (nM), Ref: 19438238
Ki: 1 (nM), Ref: 20684563
Ki: 1.47 (nM), Ref: 25147929

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2051
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 42 (ug/ml), Ref: 22280816
MIC: 42.1 (ug/ml), Ref: 26112067
TCMC2598
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Ra MIC: 25 (ug/ml), Ref: 19456117
TCMC2598
TCMT1247 Human herpesvirus 1 Human herpesvirus 1 IC50: 50 (ug/ml), Ref: 19456117