Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC879	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 230 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2013	TCMT223	Aldose reductase	Homo sapiens	IC50: 2700 (nM), Ref: 22261024
TCMC704	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 4000 (nM), Ref: 21030469 IC50: 3600 (nM), Ref: 21030469
TCMC2061	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 9550 (nM), Ref:
TCMC415	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 1800 (nM), Ref: 14592472
TCMC795	TCMT223	Aldose reductase	Homo sapiens	IC50: 8000 (nM), Ref: 24341381
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC416	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 4500 (nM), Ref: 14592472
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC719	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 14 (nM), Ref: 10891110 IC50: 115 (nM), Ref: 11597415
TCMC719	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 40 (nM), Ref: 10891110 Ki: 40 (nM), Ref: 9622546 Ki: 2454.71 (nM), Ref: 18182302
TCMC719	TCMT551	Muscarinic acetylcholine receptor M4	Homo sapiens	Ki: 2400 (nM), Ref: 10891110 Ki: 26 (nM), Ref: 10891110 Ki: 2400 (nM), Ref: 9622546
TCMC1735	TCMT599	Ubiquitin-conjugating enzyme E2 N	Homo sapiens	IC50: 8695 (nM), Ref: IC50: 5771 (nM), Ref: IC50: 6662 (nM), Ref:
TCMC1104	TCMT678	Inhibitor of apoptosis protein 3	Homo sapiens	IC50: 4100 (nM), Ref: 15115387
TCMC1104	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1700 (nM), Ref: 25765759 IC50: 60 (nM), Ref: 25765759 IC50: 800 (nM), Ref: 25765759 IC50: 60 (nM), Ref: 25765759 IC50: 3500 (nM), Ref: 25765759
TCMC1104	TCMT679	Macrophage-expressed gene 1 protein	Homo sapiens	IC50: 210 (nM), Ref: 25765759 IC50: 210 (nM), Ref: 25765759
TCMC1104	TCMT680	Histone acetyltransferase PCAF	Homo sapiens	IC50: 7200 (nM), Ref: 26701186
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC2124	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 4703 (nM), Ref:
TCMC2124	TCMT289	Thromboxane-A synthase	Homo sapiens	IC50: 325 (nM), Ref:
TCMC1113	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC2003	TCMT82	Estrogen receptor alpha	Homo sapiens	Ki: 785 (nM), Ref: 15634023
TCMC2003	TCMT164	Cyclooxygenase-1	Homo sapiens	IC50: 2840 (nM), Ref: 16814546 IC50: 4120 (nM), Ref: 18063374 IC50: 625 (nM), Ref:
TCMC2003	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 996 (nM), Ref: 17604631 IC50: 750 (nM), Ref: 20527891 IC50: 996 (nM), Ref: 26850006
TCMC2003	TCMT329	Quinone reductase 2	Homo sapiens	IC50: 960 (nM), Ref: 19265439 IC50: 450 (nM), Ref: 20036559 IC50: 450 (nM), Ref: 20356739 IC50: 960 (nM), Ref: 21261296 IC50: 6900 (nM), Ref: 23953689 Ki: 88 (nM), Ref: 23953689 IC50: 1400 (nM), Ref: 26854376 IC50: 913 (nM), Ref: 26854376
TCMC2003	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2210 (nM), Ref: 20674354
TCMC2003	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2770 (nM), Ref: 20674354
TCMC2003	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 9090 (nM), Ref: 20674354
TCMC2003	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4470 (nM), Ref: 20674354
TCMC2003	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4750 (nM), Ref: 20674354
TCMC2003	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4640 (nM), Ref: 20674354
TCMC2003	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8070 (nM), Ref: 20674354
TCMC2003	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4350 (nM), Ref: 20674354
TCMC2003	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 810 (nM), Ref: 20674354
TCMC2003	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 950 (nM), Ref: 20674354
TCMC2003	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4090 (nM), Ref: 20674354
TCMC2003	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 830 (nM), Ref: 20674354
TCMC2003	TCMT729	PI3-kinase p110-alpha subunit	Homo sapiens	IC50: 250 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT730	PI3-kinase p110-beta subunit	Homo sapiens	IC50: 500 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4100 (nM), Ref: 27190601 IC50: 2600 (nM), Ref: 27190601
TCMC1334	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 4200 (nM), Ref: 19481465
TCMC1334	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 5610 (nM), Ref: 24900561 Ki: 5.61 (nM), Ref: 27078864
TCMC1334	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 6460 (nM), Ref: 24900561 Ki: 6.46 (nM), Ref: 27078864
TCMC143	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 1610 (nM), Ref:
TCMC706	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 9510 (nM), Ref: 19028102
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1281	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 10 (nM), Ref: 19564108 IC50: 18.6 (nM), Ref: 22148241 IC50: 6 (nM), Ref: 22360639
TCMC1281	TCMT209	11-beta-hydroxysteroid dehydrogenase 2	Homo sapiens	IC50: 1 (nM), Ref: 19564108 IC50: 0.7 (nM), Ref: 22148241 IC50: 0.4 (nM), Ref: 22360639
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC2063	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 126 (nM), Ref: 12825922 IC50: 180 (nM), Ref: 18983139 Ki: 110 (nM), Ref: 18983139 IC50: 184 (nM), Ref: 18588282 Ki: 170 (nM), Ref: 21726069 IC50: 280 (nM), Ref: 23582449 Ki: 82 (nM), Ref: 23466604 IC50: 160 (nM), Ref: 23466604 IC50: 180 (nM), Ref: 26988801
TCMC2063	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 65 (nM), Ref: 12825922 Ki: 100 (nM), Ref: 15357994 IC50: 200 (nM), Ref: 18983139 Ki: 93 (nM), Ref: 18983139 IC50: 262 (nM), Ref: 18588282 IC50: 27.5 (nM), Ref: 20170099 Ki: 84 (nM), Ref: 21726069 Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8 IC50: 180 (nM), Ref: 23582449 Ki: 50 (nM), Ref: 23466604 IC50: 100 (nM), Ref: 23466604 Ki: 33 (nM), Ref: 24805037 Ki: 33 (nM), Ref: 25557493 IC50: 120 (nM), Ref: 26988801 Ki: 100 (nM), Ref: 26996373
TCMC2063	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 8.1 (nM), Ref: 12825922 IC50: 0.61 (nM), Ref: 18983139 Ki: 0.22 (nM), Ref: 18983139 IC50: 2.55 (nM), Ref: 12713409 IC50: 1.5 (nM), Ref: 18588282 Ki: 0.13 (nM), Ref: 21726069 IC50: 0.49 (nM), Ref: 23582449 Ki: 0.11 (nM), Ref: 23466604 IC50: 0.29 (nM), Ref: 23466604 Ki: 1.4 (nM), Ref: 24763360 Ki: 0.8 (nM), Ref: 24805037 Ki: 0.8 (nM), Ref: 25557493 IC50: 0.25 (nM), Ref: 26988801
TCMC2063	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 14 (nM), Ref: 15081042 Ki: 8.2 (nM), Ref: 16392816 Ki: 14 (nM), Ref: 16257207 Ki: 120 (nM), Ref: 18468904 Ki: 160 (nM), Ref: 18468904 Ki: 130 (nM), Ref: 18468904 Ki: 150 (nM), Ref: 18468904 Ki: 320 (nM), Ref: 11975483 Ki: 690 (nM), Ref: 17067154 Ki: 323.59 (nM), Ref: 23301527 Ki: 320 (nM), Ref: 23301527
TCMC2063	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 12 (nM), Ref: 15081042 Ki: 13 (nM), Ref: 12954071 Ki: 13 (nM), Ref: 16392816 Ki: 12 (nM), Ref: 16257207 Ki: 13.49 (nM), Ref: 24582985
TCMC2063	TCMT314	Serotonin 2c (5-HT2c) receptor	Homo sapiens	Ki: 6.9 (nM), Ref: 15081042 Ki: 8.3 (nM), Ref: 12954071 Ki: 8.3 (nM), Ref: 16392816 Ki: 6.9 (nM), Ref: 16257207 Ki: 130 (nM), Ref: 11975483 Ki: 20 (nM), Ref: 17067154 Ki: 79.43 (nM), Ref: 23301527 Ki: 79 (nM), Ref: 23301527
TCMC2063	TCMT815	Serotonin 1d (5-HT1d) receptor	Homo sapiens	Ki: 5.5 (nM), Ref: 8071931 Ki: 0.5 (nM), Ref: 18507369
TCMC2063	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 2.5 (nM), Ref: 7658447 IC50: 1.2 (nM), Ref: 12954071 Ki: 1.259 (nM), Ref: 18433113 Ki: 10000 (nM), Ref: 18433113 Ki: 0.62 (nM), Ref: 22748706 Ki: 0.9 (nM), Ref: 23332346 Ki: 9.5 (nM), Ref: 24161678 Ki: 2.08 (nM), Ref: 25128671
TCMC2063	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 79 (nM), Ref: 16250647
TCMC2063	TCMT816	Serotonin 1b (5-HT1b) receptor	Homo sapiens	Ki: 1.1 (nM), Ref: 18507369 IC50: 29 (nM), Ref: 18983139 Ki: 18 (nM), Ref: 18983139 Ki: 14 (nM), Ref: 21726069 IC50: 12 (nM), Ref: 23582449 Ki: 4 (nM), Ref: 23466604 IC50: 6.5 (nM), Ref: 23466604
TCMC2063	TCMT817	Serotonin 4 (5-HT4) receptor	Homo sapiens	Ki: 1049 (nM), Ref: 19334715 Ki: 500 (nM), Ref: 17067154 Ki: 29.51 (nM), Ref: 19223092 Ki: 109.65 (nM), Ref: 19223092
TCMC2063	TCMT645	Serotonin 1e (5-HT1e) receptor	Homo sapiens	Ki: 10.72 (nM), Ref: 24365159 Ki: 11 (nM), Ref: 24365159
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC755	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	Ki: 600 (nM), Ref: 21739938
TCMC755	TCMT81	Arachidonate 12-lipoxygenase	Homo sapiens	Ki: 1600 (nM), Ref: 21739938
TCMC755	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC755	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 4400 (nM), Ref: 21030469 IC50: 7000 (nM), Ref: 21030469
TCMC755	TCMT384	G protein-coupled receptor kinase 6	Homo sapiens	IC50: 8700 (nM), Ref:
TCMC1105	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 2000 (nM), Ref: 19414254
TCMC1105	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2500 (nM), Ref: 27173800
TCMC732	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 5900 (nM), Ref: 21561086
TCMC1203	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 8000 (nM), Ref: 10.1039/C4MD00086B
TCMC1204	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2500 (nM), Ref: 14592472
TCMC1523	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 1440 (nM), Ref: 24900561
TCMC1523	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 3150 (nM), Ref: 24900561
TCMC4	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 6000 (nM), Ref: 14592472
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC785	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 610 (nM), Ref: 23062825
TCMC2004	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 800 (nM), Ref: 10.1039/C3MD00317E Ki: 2100 (nM), Ref: 10.1039/C0MD00242A
TCMC2004	TCMT215	Cytochrome P450 1A1	Homo sapiens	Ki: 160 (nM), Ref: 10.1039/C0MD00242A
TCMC1892	TCMT508	Tyrosine-protein kinase SYK	Homo sapiens	IC50: 10000 (nM), Ref: 23917087
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1828	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 900 (nM), Ref: 17994701
TCMC2018	TCMT907	Farnesyl diphosphate synthase	Homo sapiens	IC50: 452.9 (nM), Ref: 18327899 Ki: 82.2 (nM), Ref: 18327899 IC50: 5.7 (nM), Ref: 18327899 Ki: 0.36 (nM), Ref: 18327899 IC50: 5.7 (nM), Ref: 18434151 IC50: 300 (nM), Ref: 20801032 IC50: 11 (nM), Ref: 22390415 IC50: 860 (nM), Ref: 22390415 IC50: 11 (nM), Ref: 22884353 IC50: 10 (nM), Ref: 21780776 IC50: 5.2 (nM), Ref: 23998921 IC50: 11 (nM), Ref: 23998921 IC50: 6 (nM), Ref: 24911527 IC50: 11 (nM), Ref: 25630225 IC50: 6 (nM), Ref: 25935643 IC50: 0.36 (nM), Ref: 25815158 IC50: 82 (nM), Ref: 25815158
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2124	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 50 (ug/ml), Ref: 1710653
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC1425	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 71 (ug/ml), Ref: 1710653 IC50: 71 (ug/ml), Ref: 21295891
TCMC2063	TCMT1086	Isocitrate lyase	Candida albicans	IC50: 53 (ug/ml), Ref: 21035332
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1203	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28.5 (ug/ml), Ref: 9461665
TCMC785	TCMT1104	Sortase	Staphylococcus aureus	IC50: 8.7 (ug/ml), Ref: 17716892 IC50: 8.7 (ug/ml), Ref: 19269184
TCMC785	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 100 (ug/ml), Ref: 1710653 IC50: 100 (ug/ml), Ref: 21295891
TCMC785	TCMT1154	Sortase	Staphylococcus aureus	IC50: 40.6 (ug/ml), Ref: 26551342
TCMC1491	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 0.00423 (ug/ml), Ref: 21334901 IC50: 0.00211 (ug/ml), Ref: 21334901
TCMC2304	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28.3 (ug/ml), Ref: 9461665
TCMC2013	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812
TCMC795	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.6 (ug/ml), Ref: 15844943
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2398	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.557 (ug/ml), Ref: 3286870 IC50: 2.008 (ug/ml), Ref: 3286870
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC1104	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1104	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 35.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 49 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 14.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1113	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 15863332
TCMC2003	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1251	Candida albicans	Candida albicans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1246	Escherichia coli	Escherichia coli	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12036362
TCMC2003	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753
TCMC2003	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 25 (ug/ml), Ref: 20022753
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1425	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.422 (ug/ml), Ref: 3286870 IC50: 1.607 (ug/ml), Ref: 3286870
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2528	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC755	TCMT1251	Candida albicans	Candida albicans	IC50: 6 (ug/ml), Ref: 12502337
TCMC755	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC755	TCMT1249	Dengue virus 2	Dengue virus 2	IC50: 6.46 (ug/ml), Ref: 25564380
TCMC1105	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 23534483
TCMC1105	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1 (ug/ml), Ref: 23534483
TCMC1105	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 23534483 MIC: 4 (ug/ml), Ref: 23534483
TCMC732	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 9 (ug/ml), Ref: 9748372
TCMC1203	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 22.6 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2014	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 10 (ug/ml), Ref: 17220400
TCMC1523	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 12.5 (ug/ml), Ref: 18611050 MIC: 25 (ug/ml), Ref: 21131198 MIC: 25 (ug/ml), Ref: 21401117 MIC: 16 (ug/ml), Ref: 22424614 MIC: 32 (ug/ml), Ref: 22424614 MBC: 32 (ug/ml), Ref: 22424614
TCMC1523	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 6.25 (ug/ml), Ref: 18611050 MIC: 12.5 (ug/ml), Ref: 21131198
TCMC1523	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 12.5 (ug/ml), Ref: 18611050 MIC: 12.5 (ug/ml), Ref: 21131198 MIC: 12.5 (ug/ml), Ref: 21401117
TCMC1523	TCMT1201	Staphylococcus epidermidis ATCC 12228	Staphylococcus epidermidis ATCC 12228	MIC: 12.5 (ug/ml), Ref: 21401117
TCMC1523	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 12.5 (ug/ml), Ref: 21401117
TCMC1523	TCMT1219	Enterococcus	Enterococcus	MIC: 32 (ug/ml), Ref: 22424614 MBC: 32 (ug/ml), Ref: 22424614
TCMC1733	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 17.2 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC785	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.36 (ug/ml), Ref: 10.1016/S0960-894X(00)80357-1 IC50: 0.141 (ug/ml), Ref: 3286870 IC50: 0.148 (ug/ml), Ref: 3286870
TCMC785	TCMT1246	Escherichia coli	Escherichia coli	MIC: 5 (ug/ml), Ref: 16359864 MIC: 31.25 (ug/ml), Ref: 18591276
TCMC785	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 16730982 MIC: 31.3 (ug/ml), Ref: 16872133
TCMC785	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 17716892 MIC: 50 (ug/ml), Ref: 9784149 MIC: 60 (ug/ml), Ref: 15568768 MBC: 64 (ug/ml), Ref: 10.1007/s00044-013-0844-5 MIC: 32 (ug/ml), Ref: 10.1007/s00044-013-0844-5
TCMC785	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 100 (ug/ml), Ref: 9784149
TCMC785	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 25 (ug/ml), Ref: 9784149
TCMC785	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 9784149 MIC: 31.3 (ug/ml), Ref: 16872133 MIC: 15.6 (ug/ml), Ref: 16872133
TCMC785	TCMT1385	Candida shehatae	Candida shehatae	MIC: 7.8 (ug/ml), Ref: 16872133
TCMC1892	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753 MBC: 100 (ug/ml), Ref: 20022753
TCMC1892	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 50 (ug/ml), Ref: 20022753 MBC: 100 (ug/ml), Ref: 20022753
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1491	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 0.92 (ug/ml), Ref: 21334901
TCMC1491	TCMT1318	Human T-lymphotropic virus 1	Human T-lymphotropic virus 1	IC50: 1.07 (ug/ml), Ref: 21334901
TCMC1828	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.281 (ug/ml), Ref: 3286870 IC50: 0.163 (ug/ml), Ref: 3286870
TCMC2699	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 6.3 (ug/ml), Ref: 14995101
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2806	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.5 (ug/ml), Ref: 18524594
TCMC2808	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 27 (ug/ml), Ref: 10425115
TCMC2811	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.35 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001
TCMC1113	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 16 (nM), Ref: 17263522
TCMC4	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 40 (nM), Ref: 16722653
TCMC2018	TCMT1155	Farnesyl pyrophosphate synthase	Leishmania major	Ki: 17 (nM), Ref: 15828834
TCMC1047	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 50 (nM), Ref: 24549242