TCM Putative Target References: TCMFx6533


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1786
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 3900 (nM), Ref: 16580200
IC50: 7600 (nM), Ref: 18798681
IC50: 4200 (nM), Ref: 19702283
IC50: 3840 (nM), Ref: 22044245
IC50: 5600 (nM), Ref: 22690646
IC50: 9500 (nM), Ref: 21453996
Ki: 6000 (nM), Ref: 21453996
IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 2600 (nM), Ref: 23357636
IC50: 1100 (nM), Ref: 23434422
IC50: 3020 (nM), Ref: 23942421
IC50: 2010 (nM), Ref: 24090912
IC50: 1900 (nM), Ref: 24684845
IC50: 3020 (nM), Ref: 25497963
IC50: 9500 (nM), Ref: 25264584
Ki: 6000 (nM), Ref: 25264584
IC50: 1030 (nM), Ref: 25595683
IC50: 1170 (nM), Ref: 25600405
IC50: 3020 (nM), Ref: 25872983
IC50: 1000 (nM), Ref: 26083682
IC50: 1536 (nM), Ref: 26100442
IC50: 700 (nM), Ref: 26115570
IC50: 700 (nM), Ref: 26253631
IC50: 1536 (nM), Ref: 26481657
IC50: 730 (nM), Ref: 26711144
IC50: 3020 (nM), Ref: 26774579
IC50: 1536 (nM), Ref: 27123900
TCMC1786
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 4000 (nM), Ref: 21561086
Ki: 3560 (nM), Ref: 21561086
Ki: 660 (nM), Ref: 21561086
Ki: 940 (nM), Ref: 21561086
Ki: 160 (nM), Ref: 21561086
Ki: 72 (nM), Ref: 21561086
IC50: 90 (nM), Ref: 21561086
TCMC1786
TCMT190 T-cell protein-tyrosine phosphatase Homo sapiens IC50: 4230 (nM), Ref: 24684845
IC50: 4440 (nM), Ref: 25497963
IC50: 5460 (nM), Ref: 26100442
IC50: 5460 (nM), Ref: 26481657
IC50: 5460 (nM), Ref: 27123900
TCMC1786
TCMT563 Dual specificity phosphatase Cdc25B Homo sapiens IC50: 980 (nM), Ref: 25497963
TCMC2111
TCMT614 Egl nine homolog 1 Homo sapiens IC50: 3000 (nM), Ref: 18942826

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1786
TCMT1107 Protease Human immunodeficiency virus 1 IC50: 10 (ug/ml), Ref: 10691716
TCMC2411
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 16 (ug/ml), Ref: 11141098
TCMC2411
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 64 (ug/ml), Ref: 12608857
TCMC1786
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 50 (ug/ml), Ref: 11141098
MIC: 100 (ug/ml), Ref: 18798682
MIC: 64 (ug/ml), Ref: 15387646
MIC: 29 (ug/ml), Ref: 23356207
TCMC1786
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 21.8 (ug/ml), Ref: 9748372
TCMC1786
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 16 (ug/ml), Ref: 21288041
TCMC1786
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 50 (ug/ml), Ref: 11141098
MIC: 100 (ug/ml), Ref: 18798682
MIC: 64 (ug/ml), Ref: 15387646
MIC: 29 (ug/ml), Ref: 23356207
TCMC2478
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 0.1904 (ug/ml), Ref: 9644053
TCMC2478
TCMT1438 Plasmodium falciparum Plasmodium falciparum NF54 IC50: 0.2709 (ug/ml), Ref: 9644053
TCMC2642
TCMT1251 Candida albicans Candida albicans IC50: 3.5 (ug/ml), Ref: 12088427
MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans MIC: 12.5 (ug/ml), Ref: 12088427
IC50: 2 (ug/ml), Ref: 12088427
TCMC2642
TCMT1218 Staphylococcus aureus Staphylococcus aureus IC50: 2 (ug/ml), Ref: 12088427
MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642
TCMT1355 Rhodococcus equi Rhodococcus equi MIC: 10 (ug/ml), Ref: 19639965
TCMC2642
TCMT1439 Mycobacterium smegmatis Mycobacterium smegmatis MIC: 12 (ug/ml), Ref: 19874044
TCMC2642
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 50 (ug/ml), Ref: 20476748
TCMC2642
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 12.5 (ug/ml), Ref: 22280816
TCMC2696
TCMT1354 Streptococcus mutans UA159 Streptococcus mutans UA159 MIC: 80 (ug/ml), Ref: 10.1007/s00044-011-9658-5