Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2093	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 57 (nM), Ref: 17149865
TCMC2093	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 68 (nM), Ref: 17149865
TCMC758	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	Ki: 175.5 (nM), Ref: 25978962 IC50: 488.8 (nM), Ref: 25978962
TCMC949	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 19911821
TCMC949	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 48 (nM), Ref: 19911821
TCMC949	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9100 (nM), Ref: 19911821
TCMC949	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3300 (nM), Ref: 19911821
TCMC949	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 2000 (nM), Ref: 19911821
TCMC949	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 5200 (nM), Ref: 19911821
TCMC949	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9400 (nM), Ref: 19911821
TCMC949	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 6800 (nM), Ref: 19911821
TCMC949	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 5600 (nM), Ref: 19911821
TCMC949	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 19911821 Ki: 3100 (nM), Ref: 21067924 Ki: 3100 (nM), Ref: 22137345 Ki: 3100 (nM), Ref: 22077347 Ki: 3100 (nM), Ref: 22365761 Ki: 3100 (nM), Ref: 22377674 Ki: 3100 (nM), Ref: 23241068 Ki: 3100 (nM), Ref: 22892213 Ki: 3100 (nM), Ref: 26688270
TCMC949	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 21067924 Ki: 9200 (nM), Ref: 22137345 Ki: 9200 (nM), Ref: 22077347 Ki: 9200 (nM), Ref: 22365761 Ki: 9200 (nM), Ref: 22377674 Ki: 9200 (nM), Ref: 23241068 Ki: 9200 (nM), Ref: 22892213 Ki: 9200 (nM), Ref: 26688270
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1113	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1774	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 20674354 Ki: 3100 (nM), Ref: 21282059 Ki: 3400 (nM), Ref: 22137345
TCMC1774	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9300 (nM), Ref: 22137345
TCMC1551	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1900 (nM), Ref: 16248836 Ki: 1900 (nM), Ref: 16248836 Ki: 800 (nM), Ref: 16248836 Ki: 250 (nM), Ref: 22696418
TCMC1551	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 760 (nM), Ref: 23746477
TCMC1551	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 40 (nM), Ref: 22696418
TCMC2201	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 8700 (nM), Ref: 21332115
TCMC679	TCMT624	Heat shock protein HSP 90-beta	Homo sapiens	IC50: 930 (nM), Ref: 7853008 IC50: 1410 (nM), Ref: IC50: 24 (nM), Ref: 10.1007/s00044-012-0301-x IC50: 90 (nM), Ref: 19734910
TCMC679	TCMT619	Heat shock protein HSP 90-alpha	Homo sapiens	Ki: 680 (nM), Ref:
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477
TCMC1343	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 90 (nM), Ref: 18501600 Ki: 90 (nM), Ref: 18579385
TCMC1343	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7800 (nM), Ref: 18579385
TCMC1343	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8200 (nM), Ref: 18579385

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1381	TCMT1251	Candida albicans	Candida albicans	IC50: 3 (ug/ml), Ref: 17112640 IC50: 2 (ug/ml), Ref: 12502337
TCMC1381	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 7 (ug/ml), Ref: 17112640 IC50: 45 (ug/ml), Ref: 12502337
TCMC1381	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 31.2 (ug/ml), Ref: 18951808
TCMC1381	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 31.2 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.62 (ug/ml), Ref: 22169259
TCMC1381	TCMT1246	Escherichia coli	Escherichia coli	MIC: 2 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051 MIC: 0.25 (ug/ml), Ref: 20160051 MIC: 8 (ug/ml), Ref: 20160051
TCMC1381	TCMT1179	Escherichia coli ATCC 8739	Escherichia coli ATCC 8739	MIC: 8 (ug/ml), Ref: 20160051
TCMC1381	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 16 (ug/ml), Ref: 20160051 MIC: 32 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051 MIC: 8 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051
TCMC1381	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 32 (ug/ml), Ref: 20160051 MIC: 4 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051
TCMC1381	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 64 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051
TCMC1381	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 64 (ug/ml), Ref: 20160051 MIC: 4 (ug/ml), Ref: 20160051
TCMC1381	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 8 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051 MIC: 1 (ug/ml), Ref: 20160051
TCMC1381	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 18 (ug/ml), Ref: 22280816
TCMC2362	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 32 (ug/ml), Ref: 20427099
TCMC2362	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 1 (ug/ml), Ref: 20427099
TCMC2362	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 1 (ug/ml), Ref: 20427099
TCMC2362	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 1 (ug/ml), Ref: 20427099
TCMC2374	TCMT1251	Candida albicans	Candida albicans	IC50: 5 (ug/ml), Ref: 12502337
TCMC2374	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 7.5 (ug/ml), Ref: 12502337
TCMC2093	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 12932139
TCMC2093	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 12932139
TCMC1113	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 15863332
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC2544	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.2 (ug/ml), Ref: 7964799
TCMC2544	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 50 (ug/ml), Ref: 7964799
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC915	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 25791674
TCMC915	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC1955	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4.17 (ug/ml), Ref: 24549242
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC1551	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 20832915
TCMC2747	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MBC: 16 (ug/ml), Ref: 15958589 MIC: 16 (ug/ml), Ref: 15958589
TCMC2747	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MBC: 64 (ug/ml), Ref: 15958589 MIC: 32 (ug/ml), Ref: 15958589
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915
TCMC2818	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 64 (ug/ml), Ref: 20427099
TCMC1113	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 16 (nM), Ref: 17263522