Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1328	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1970 (nM), Ref: 23062825
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC1609	TCMT44	Glyoxalase I	Homo sapiens	IC50: 560 (nM), Ref: 18258440 IC50: 560 (nM), Ref: 21669529
TCMC1609	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18778944
TCMC1609	TCMT737	DNA dC->dU-editing enzyme APOBEC-3G	Homo sapiens	IC50: 2390 (nM), Ref:
TCMC1609	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 2120 (nM), Ref: 24900447
TCMC1609	TCMT558	DNA topoisomerase II alpha	Homo sapiens	IC50: 390 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC1609	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2800 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1609	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1609	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1690 (nM), Ref: 23411073
TCMC1609	TCMT2	Microtubule-associated protein tau	Homo sapiens	IC50: 1200 (nM), Ref: 23484434 IC50: 3000 (nM), Ref: 25086914
TCMC1609	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC1609	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 3000 (nM), Ref: 25086914
TCMC1609	TCMT740	PI3-kinase p110-gamma subunit	Homo sapiens	IC50: 4720 (nM), Ref: 25050878
TCMC1609	TCMT13	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	IC50: 320 (nM), Ref: 25280182
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1787	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3500 (nM), Ref: 18798681 IC50: 5320 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 5320 (nM), Ref: 10.1007/s00044-010-9529-5
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1856	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 500 (nM), Ref: 20590092
TCMC1856	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 52 (nM), Ref: 20590092
TCMC1856	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 44 (nM), Ref: 20590092
TCMC1856	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 540 (nM), Ref: 20590092
TCMC1856	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 740 (nM), Ref: 20590092
TCMC1856	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 420 (nM), Ref: 20590092
TCMC1856	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 380 (nM), Ref: 20590092
TCMC1856	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 450 (nM), Ref: 20590092
TCMC1856	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 500 (nM), Ref: 20590092
TCMC2209	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 3400 (nM), Ref: 23388705 IC50: 5400 (nM), Ref: 23388705
TCMC2209	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 5200 (nM), Ref: 23388705 IC50: 5800 (nM), Ref: 23388705
TCMC2216	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3600 (nM), Ref: 17489632 IC50: 3100 (nM), Ref: 18798681 IC50: 3600 (nM), Ref: 19008110 IC50: 3600 (nM), Ref: 17125223 IC50: 3800 (nM), Ref: 19846295 IC50: 3900 (nM), Ref: 19632832 IC50: 3600 (nM), Ref: 19836230 IC50: 3100 (nM), Ref: 21555221 IC50: 3600 (nM), Ref: 21571537 IC50: 3100 (nM), Ref: 22940448 IC50: 2300 (nM), Ref: 21453996 Ki: 3400 (nM), Ref: 21453996 IC50: 3600 (nM), Ref: 23022281 IC50: 3080 (nM), Ref: 23141910 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2750 (nM), Ref: 23387824 IC50: 4120 (nM), Ref: 24224843 IC50: 4000 (nM), Ref: 24953600 IC50: 3500 (nM), Ref: 25559759 IC50: 3400 (nM), Ref: 25907369 Ki: 6400 (nM), Ref: 25907369 IC50: 5200 (nM), Ref: 26841168
TCMC2216	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 1900 (nM), Ref: 20100662
TCMC2216	TCMT102	Low molecular weight phosphotyrosine protein phosphatase	Homo sapiens	IC50: 7200 (nM), Ref: 21453996
TCMC2216	TCMT103	Receptor-type tyrosine-protein phosphatase F (LAR)	Homo sapiens	IC50: 3800 (nM), Ref: 21453996
TCMC2216	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 21561086 Ki: 3700 (nM), Ref: 21561086 Ki: 2100 (nM), Ref: 21561086 Ki: 2800 (nM), Ref: 21561086 Ki: 2000 (nM), Ref: 21561086 IC50: 4000 (nM), Ref: 21561086
TCMC2216	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 2400 (nM), Ref: 23387824
TCMC2216	TCMT150	Nuclear receptor ROR-gamma	Homo sapiens	IC50: 680 (nM), Ref: 10.1039/C3MD00005B IC50: 130 (nM), Ref: 24704616 IC50: 1060 (nM), Ref: 24704616 IC50: 9410 (nM), Ref: 24704616
TCMC265	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 91 (nM), Ref: 23332346
TCMC265	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 4.5 (nM), Ref: 23332346
TCMC702	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 5150 (nM), Ref: 15658857
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2177	TCMT1120	Cell division protein ftsZ	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 25791674
TCMC1609	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 26.29 (ug/ml), Ref: 20116898
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2177	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 1.56 (ug/ml), Ref: 1453180 MIC: 0.6 (ug/ml), Ref: 25791674
TCMC2177	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 1453180 MIC: 0.78 (ug/ml), Ref: 1453180 MIC: 2.5 (ug/ml), Ref: 17664318 MIC: 1.25 (ug/ml), Ref: 17664318 MIC: 16 (ug/ml), Ref: 17664318 MIC: 2 (ug/ml), Ref: 17664318 MIC: 1.5 (ug/ml), Ref: 25791674
TCMC2177	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 0.78 (ug/ml), Ref: 1453180
TCMC2177	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 16 (ug/ml), Ref: 25791674
TCMC1609	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 0.88 (ug/ml), Ref: 24749980
TCMC1609	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1609	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1609	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC1787	TCMT1346	Helicobacter pylori	Helicobacter pylori	MBC: 0.292 (ug/ml), Ref: 17116667
TCMC1787	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 16 (ug/ml), Ref: 11141098
TCMC1787	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 0.8 (ug/ml), Ref: 9748372
TCMC1955	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4.17 (ug/ml), Ref: 24549242
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC2216	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 6.5 (ug/ml), Ref: 9748372
TCMC2216	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 100 (ug/ml), Ref: 20542692
TCMC2216	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC2821	TCMT1251	Candida albicans	Candida albicans	MIC: 1.56 (ug/ml), Ref: 7760078 MFC: 3.12 (ug/ml), Ref: 7760078 MFC: 6.25 (ug/ml), Ref: 7760078 MIC: 3.125 (ug/ml), Ref: 10346966 MFC: 6.25 (ug/ml), Ref: 10346966 MIC: 6.25 (ug/ml), Ref: 18611050 MIC: 6.25 (ug/ml), Ref: 21131198
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001