Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2013	TCMT223	Aldose reductase	Homo sapiens	IC50: 2700 (nM), Ref: 22261024
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC22	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 1000 (nM), Ref: 15679319 Ki: 177 (nM), Ref: 16248836
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC785	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 610 (nM), Ref: 23062825
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1828	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 900 (nM), Ref: 17994701
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1425	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 71 (ug/ml), Ref: 1710653 IC50: 71 (ug/ml), Ref: 21295891
TCMC785	TCMT1104	Sortase	Staphylococcus aureus	IC50: 8.7 (ug/ml), Ref: 17716892 IC50: 8.7 (ug/ml), Ref: 19269184
TCMC785	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 100 (ug/ml), Ref: 1710653 IC50: 100 (ug/ml), Ref: 21295891
TCMC785	TCMT1154	Sortase	Staphylococcus aureus	IC50: 40.6 (ug/ml), Ref: 26551342
TCMC1491	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 0.00423 (ug/ml), Ref: 21334901 IC50: 0.00211 (ug/ml), Ref: 21334901
TCMC2013	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2398	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.557 (ug/ml), Ref: 3286870 IC50: 2.008 (ug/ml), Ref: 3286870
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC2417	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25760525 MIC: 32 (ug/ml), Ref: 25760525
TCMC2417	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 25760525
TCMC2482	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2482	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2482	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.1 (ug/ml), Ref: 9392889
TCMC2482	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 3.1 (ug/ml), Ref: 9392889
TCMC2482	TCMT1251	Candida albicans	Candida albicans	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC2506	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.99 (ug/ml), Ref: 8786363 IC50: 1.9 (ug/ml), Ref: 8786363
TCMC1425	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.422 (ug/ml), Ref: 3286870 IC50: 1.607 (ug/ml), Ref: 3286870
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2606	TCMT1248	Hepatitis C virus	Hepatitis C virus	IC50: 20 (ug/ml), Ref: 19904996
TCMC2642	TCMT1251	Candida albicans	Candida albicans	IC50: 3.5 (ug/ml), Ref: 12088427 MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 12088427 IC50: 2 (ug/ml), Ref: 12088427
TCMC2642	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 2 (ug/ml), Ref: 12088427 MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642	TCMT1355	Rhodococcus equi	Rhodococcus equi	MIC: 10 (ug/ml), Ref: 19639965
TCMC2642	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 12 (ug/ml), Ref: 19874044
TCMC2642	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC2642	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC785	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.36 (ug/ml), Ref: 10.1016/S0960-894X(00)80357-1 IC50: 0.141 (ug/ml), Ref: 3286870 IC50: 0.148 (ug/ml), Ref: 3286870
TCMC785	TCMT1246	Escherichia coli	Escherichia coli	MIC: 5 (ug/ml), Ref: 16359864 MIC: 31.25 (ug/ml), Ref: 18591276
TCMC785	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 16730982 MIC: 31.3 (ug/ml), Ref: 16872133
TCMC785	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 17716892 MIC: 50 (ug/ml), Ref: 9784149 MIC: 60 (ug/ml), Ref: 15568768 MBC: 64 (ug/ml), Ref: 10.1007/s00044-013-0844-5 MIC: 32 (ug/ml), Ref: 10.1007/s00044-013-0844-5
TCMC785	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 100 (ug/ml), Ref: 9784149
TCMC785	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 25 (ug/ml), Ref: 9784149
TCMC785	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 9784149 MIC: 31.3 (ug/ml), Ref: 16872133 MIC: 15.6 (ug/ml), Ref: 16872133
TCMC785	TCMT1385	Candida shehatae	Candida shehatae	MIC: 7.8 (ug/ml), Ref: 16872133
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1491	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 0.92 (ug/ml), Ref: 21334901
TCMC1491	TCMT1318	Human T-lymphotropic virus 1	Human T-lymphotropic virus 1	IC50: 1.07 (ug/ml), Ref: 21334901
TCMC1828	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.281 (ug/ml), Ref: 3286870 IC50: 0.163 (ug/ml), Ref: 3286870
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2733	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 4 (ug/ml), Ref: 14698179
TCMC2734	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 15715470 MIC: 64 (ug/ml), Ref: MIC: 32 (ug/ml), Ref: 19179074
TCMC2735	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 8 (ug/ml), Ref: 15715470 MIC: 8 (ug/ml), Ref: 22194678 MIC: 8 (ug/ml), Ref: 19179074
TCMC2733	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 2 (ug/ml), Ref: 19179074 MIC: 4 (ug/ml), Ref: 16643039
TCMC2735	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17190457
TCMC2735	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 20405847
TCMC2733	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 4 (ug/ml), Ref: 12617583
TCMC2734	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 12617583
TCMC2734	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17438047
TCMC2735	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 17438047
TCMC2733	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 4 (ug/ml), Ref: 17438047
TCMC2772	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25856683 MIC: 8 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 16 (ug/ml), Ref: 15497933
TCMC2772	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 15679329
TCMC2772	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 18541727
TCMC2772	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref:
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2811	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.35 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1047	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 50 (nM), Ref: 24549242