Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1957	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 78 (nM), Ref: 26125082
TCMC2001	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 6.9 (nM), Ref: 19027293 Ki: 3.9 (nM), Ref: 20055417
TCMC2001	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 180 (nM), Ref: 19027293 Ki: 49 (nM), Ref: 20055417
TCMC2001	TCMT117	Kappa opioid receptor	Homo sapiens	Ki: 3 (nM), Ref: 19027293 Ki: 2.2 (nM), Ref: 20055417
TCMC1258	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 966 (nM), Ref: 25695425
TCMC1258	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 43 (nM), Ref: 25695425
TCMC1258	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 171 (nM), Ref: 25695425
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1851	TCMT560	Coagulation factor X	Homo sapiens	IC50: 170 (nM), Ref: 9834152 Ki: 570 (nM), Ref: 9834152
TCMC1851	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 3760 (nM), Ref: 24835197 Ki: 5130 (nM), Ref: 24835197
TCMC1851	TCMT240	Salivary alpha-amylase	Homo sapiens	IC50: 2350 (nM), Ref: 26395057 Ki: 2600 (nM), Ref: 26395057
TCMC1339	TCMT117	Kappa opioid receptor	Homo sapiens	Ki: 260 (nM), Ref: 22439881
TCMC1339	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 9.5 (nM), Ref: 22439881
TCMC1429	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 2700 (nM), Ref: 17378609
TCMC1429	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 1050 (nM), Ref: 18533708
TCMC1429	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 360 (nM), Ref: 18533708
TCMC1429	TCMT187	Androgen Receptor	Homo sapiens	IC50: 9700 (nM), Ref: 19592245
TCMC1429	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 716 (nM), Ref: 20696580
TCMC1429	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 632 (nM), Ref: 20696580
TCMC1429	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 47 (nM), Ref: 20696580
TCMC1429	TCMT223	Aldose reductase	Homo sapiens	IC50: 10000 (nM), Ref: 22261024
TCMC1429	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 2320 (nM), Ref: 23411073
TCMC1429	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 9640 (nM), Ref: 23656512
TCMC1429	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 10000 (nM), Ref: 26322379
TCMC1429	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9525.7 (nM), Ref: 26498393
TCMC1429	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 25 (nM), Ref: 26498393
TCMC1429	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 145.9 (nM), Ref: 26498393
TCMC1429	TCMT159	Tyrosinase	Homo sapiens	IC50: 1000 (nM), Ref: 26841168
TCMC1795	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 286 (nM), Ref: 17616524
TCMC7	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 9100 (nM), Ref: 15679319
TCMC1041	TCMT636	DNA polymerase alpha subunit	Homo sapiens	Ki: 830 (nM), Ref: 1705574
TCMC1041	TCMT17	DNA polymerase beta	Homo sapiens	Ki: 390 (nM), Ref: 1705574
TCMC1480	TCMT107	Glutamate receptor ionotropic kainate 2	Homo sapiens	Ki: 1106 (nM), Ref: 10821708
TCMC1480	TCMT108	Glutamate receptor ionotropic, AMPA 1	Homo sapiens	Ki: 1360 (nM), Ref: 9357531
TCMC1480	TCMT109	Glutamate receptor ionotropic, AMPA 2	Homo sapiens	Ki: 940 (nM), Ref: 9357531
TCMC1480	TCMT110	Glutamate receptor ionotropic, AMPA 4	Homo sapiens	Ki: 868 (nM), Ref: 9357531
TCMC1480	TCMT111	Glutamate receptor ionotropic kainate 5	Homo sapiens	Ki: 701 (nM), Ref: 9357531
TCMC1480	TCMT660	Metabotropic glutamate receptor 8	Homo sapiens	IC50: 5.7 (nM), Ref: 15603952
TCMC1480	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 613 (nM), Ref: 16250647
TCMC1480	TCMT653	Metabotropic glutamate receptor 1	Homo sapiens	Ki: 250 (nM), Ref: 17725337 Ki: 570 (nM), Ref: 19042134 Ki: 1584.89 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT654	Metabotropic glutamate receptor 5	Homo sapiens	Ki: 390 (nM), Ref: 17725337 Ki: 1160 (nM), Ref: 19042134 Ki: 4677.35 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT657	Metabotropic glutamate receptor 4	Homo sapiens	Ki: 2400 (nM), Ref: 17725337 Ki: 1400 (nM), Ref: 19042134 Ki: 3235.94 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT655	Metabotropic glutamate receptor 2	Homo sapiens	Ki: 6400 (nM), Ref: 19042134 Ki: 1819.7 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT664	Excitatory amino acid transporter 3	Homo sapiens	Ki: 51 (nM), Ref: 18578477
TCMC1480	TCMT656	Metabotropic glutamate receptor 3	Homo sapiens	Ki: 57.54 (nM), Ref: 10.1039/C1MD00186H
TCMC949	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 19911821
TCMC949	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 48 (nM), Ref: 19911821
TCMC949	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9100 (nM), Ref: 19911821
TCMC949	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3300 (nM), Ref: 19911821
TCMC949	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 2000 (nM), Ref: 19911821
TCMC949	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 5200 (nM), Ref: 19911821
TCMC949	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9400 (nM), Ref: 19911821
TCMC949	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 6800 (nM), Ref: 19911821
TCMC949	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 5600 (nM), Ref: 19911821
TCMC949	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 19911821 Ki: 3100 (nM), Ref: 21067924 Ki: 3100 (nM), Ref: 22137345 Ki: 3100 (nM), Ref: 22077347 Ki: 3100 (nM), Ref: 22365761 Ki: 3100 (nM), Ref: 22377674 Ki: 3100 (nM), Ref: 23241068 Ki: 3100 (nM), Ref: 22892213 Ki: 3100 (nM), Ref: 26688270
TCMC949	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 21067924 Ki: 9200 (nM), Ref: 22137345 Ki: 9200 (nM), Ref: 22077347 Ki: 9200 (nM), Ref: 22365761 Ki: 9200 (nM), Ref: 22377674 Ki: 9200 (nM), Ref: 23241068 Ki: 9200 (nM), Ref: 22892213 Ki: 9200 (nM), Ref: 26688270
TCMC662	TCMT683	Macrophage migration inhibitory factor	Homo sapiens	IC50: 250 (nM), Ref: 25743213 IC50: 1100 (nM), Ref: 25743213
TCMC130	TCMT615	Sentrin-specific protease 8	Homo sapiens	IC50: 2470 (nM), Ref:
TCMC130	TCMT616	Sentrin-specific protease 7	Homo sapiens	IC50: 1670 (nM), Ref:
TCMC130	TCMT617	Sentrin-specific protease 6	Homo sapiens	IC50: 805 (nM), Ref:
TCMC2124	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 4703 (nM), Ref:
TCMC2124	TCMT289	Thromboxane-A synthase	Homo sapiens	IC50: 325 (nM), Ref:
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC670	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 7700 (nM), Ref: 15679319
TCMC1113	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC1325	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 8000 (nM), Ref: 15679319 Ki: 373 (nM), Ref: 16248836
TCMC1325	TCMT634	Norepinephrine transporter	Homo sapiens	IC50: 8760 (nM), Ref: 24112084
TCMC1325	TCMT635	Dopamine transporter	Homo sapiens	IC50: 8350 (nM), Ref: 24112084
TCMC1102	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 7500 (nM), Ref: 16610779
TCMC1102	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 40 (nM), Ref: 19414254
TCMC1102	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2320 (nM), Ref: 20185318
TCMC1102	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2180 (nM), Ref: 20185318
TCMC1102	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC1102	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7590 (nM), Ref: 20185318
TCMC1102	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7060 (nM), Ref: 20185318
TCMC1102	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6320 (nM), Ref: 20185318 Ki: 8790 (nM), Ref: 22892213
TCMC1102	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9370 (nM), Ref: 20185318
TCMC1102	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8910 (nM), Ref: 20185318
TCMC1102	TCMT753	Mothers against decapentaplegic homolog 3	Homo sapiens	IC50: 142 (nM), Ref:
TCMC1102	TCMT721	Heat shock 70 kDa protein 1	Homo sapiens	IC50: 760 (nM), Ref:
TCMC1102	TCMT189	Dual specificity protein phosphatase 3	Homo sapiens	IC50: 1230 (nM), Ref: IC50: 980 (nM), Ref:
TCMC1102	TCMT223	Aldose reductase	Homo sapiens	IC50: 200 (nM), Ref: 22261024
TCMC1102	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 3340 (nM), Ref: 22377675
TCMC1102	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 510 (nM), Ref: 22377675
TCMC1102	TCMT354	Serine/threonine-protein kinase Aurora-A	Homo sapiens	IC50: 2480 (nM), Ref: 22377675
TCMC1102	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 2500 (nM), Ref: 22377675
TCMC1102	TCMT626	Serine/threonine-protein kinase B-raf	Homo sapiens	IC50: 1760 (nM), Ref: 22377675
TCMC1102	TCMT423	Epidermal growth factor receptor erbB1	Homo sapiens	IC50: 690 (nM), Ref: 22377675
TCMC1102	TCMT418	Ephrin type-B receptor 4	Homo sapiens	IC50: 1830 (nM), Ref: 22377675
TCMC1102	TCMT704	Receptor protein-tyrosine kinase erbB-2	Homo sapiens	IC50: 3540 (nM), Ref: 22377675
TCMC1102	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 3110 (nM), Ref: 22377675
TCMC1102	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 250 (nM), Ref: 22377675
TCMC1102	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 800 (nM), Ref: 22377675
TCMC1102	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 790 (nM), Ref: 22377675
TCMC1102	TCMT457	Vascular endothelial growth factor receptor 3	Homo sapiens	IC50: 1540 (nM), Ref: 22377675
TCMC1102	TCMT377	Insulin receptor	Homo sapiens	IC50: 340 (nM), Ref: 22377675
TCMC1102	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 22377675
TCMC1102	TCMT536	Platelet-derived growth factor receptor beta	Homo sapiens	IC50: 1300 (nM), Ref: 22377675
TCMC1102	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 3340 (nM), Ref: 22377675
TCMC1102	TCMT755	Serine/threonine-protein kinase PLK4	Homo sapiens	IC50: 2970 (nM), Ref: 22377675
TCMC1102	TCMT502	Tyrosine-protein kinase TIE-2	Homo sapiens	IC50: 260 (nM), Ref: 22377675
TCMC1102	TCMT756	Mitogen-activated protein kinase kinase kinase 8	Homo sapiens	IC50: 2370 (nM), Ref: 22377675
TCMC1102	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 100 (nM), Ref: 24900447
TCMC1102	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8150 (nM), Ref: 22892213
TCMC1102	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4240 (nM), Ref: 22892213
TCMC1102	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 3900 (nM), Ref: 24835197
TCMC2155	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 7400 (nM), Ref: 17616524
TCMC5	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 830 (nM), Ref: 15679319 Ki: 82 (nM), Ref: 16248836
TCMC1982	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302
TCMC1982	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208
TCMC1982	TCMT223	Aldose reductase	Homo sapiens	IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999
TCMC1982	TCMT44	Glyoxalase I	Homo sapiens	IC50: 3200 (nM), Ref: 18258440
TCMC1982	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 1540 (nM), Ref: 18533708
TCMC1982	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7890 (nM), Ref: 20185318
TCMC1982	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8100 (nM), Ref: 20185318
TCMC1982	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2540 (nM), Ref: 20185318
TCMC1982	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2680 (nM), Ref: 20185318
TCMC1982	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6810 (nM), Ref: 20185318
TCMC1982	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6170 (nM), Ref: 20185318
TCMC1982	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4840 (nM), Ref: 20185318
TCMC1982	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7000 (nM), Ref: 20185318
TCMC1982	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9390 (nM), Ref: 20185318
TCMC1982	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 5410 (nM), Ref: 20185318
TCMC1158	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 3100 (nM), Ref: 24835197 Ki: 6840 (nM), Ref: 24835197
TCMC1982	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 12 (nM), Ref: 20413308
TCMC1982	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 4097 (nM), Ref: 20696580 IC50: 1550 (nM), Ref: 22328583
TCMC1982	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1191 (nM), Ref: 20696580
TCMC1982	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 77 (nM), Ref: 20696580
TCMC1982	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 6680 (nM), Ref: 22658537
TCMC1982	TCMT320	Matrix metalloproteinase 3	Homo sapiens	IC50: 5570 (nM), Ref: 22658537
TCMC1982	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 1610 (nM), Ref: 22658537
TCMC1982	TCMT322	Matrix metalloproteinase 13	Homo sapiens	IC50: 8460 (nM), Ref: 22658537
TCMC1982	TCMT422	CaM kinase II beta	Homo sapiens	IC50: 3000 (nM), Ref: 21798748
TCMC1982	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y IC50: 6500 (nM), Ref: 26003344
TCMC1982	TCMT784	Vasopressin V2 receptor	Homo sapiens	IC50: 7000 (nM), Ref: 23437772 IC50: 6309.57 (nM), Ref: 23437772
TCMC1982	TCMT785	Interleukin-8 receptor A	Homo sapiens	IC50: 4500 (nM), Ref: 23437772 IC50: 5011.87 (nM), Ref: 23437772
TCMC1982	TCMT786	C-C chemokine receptor type 4	Homo sapiens	IC50: 10000 (nM), Ref: 23437772
TCMC1982	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 590 (nM), Ref: 23411073
TCMC2053	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 22 (nM), Ref: 23332346
TCMC2053	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 214 (nM), Ref: 23332346
TCMC1982	TCMT601	Thrombin	Homo sapiens	IC50: 1500 (nM), Ref: 24610996
TCMC1837	TCMT789	Phosphodiesterase 3A	Homo sapiens	Ki: 279 (nM), Ref: 17228859
TCMC1837	TCMT790	Phosphodiesterase 3B	Homo sapiens	Ki: 417 (nM), Ref: 17228859
TCMC1982	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 280 (nM), Ref: 24328302
TCMC1982	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 120 (nM), Ref: 24328302
TCMC1982	TCMT791	Protein kinase N1	Homo sapiens	IC50: 5800 (nM), Ref: 24328302
TCMC1837	TCMT792	Phosphodiesterase 10A	Homo sapiens	IC50: 56.9 (nM), Ref: 20450197 IC50: 76 (nM), Ref: 20450197 IC50: 17 (nM), Ref: 21087867 IC50: 21 (nM), Ref: 21705115 IC50: 36 (nM), Ref: 22321214 IC50: 210 (nM), Ref: 23978358 IC50: 36 (nM), Ref: 24721831 IC50: 36 (nM), Ref: 25592707 IC50: 92.3 (nM), Ref: 10.1039/C5MD00419E
TCMC1982	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 5750 (nM), Ref: 24328302
TCMC1982	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 4230 (nM), Ref: 24328302
TCMC1982	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 5730 (nM), Ref: 24328302
TCMC1982	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 24328302
TCMC1982	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 300 (nM), Ref: 24328302
TCMC1982	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 1200 (nM), Ref: 24328302
TCMC1837	TCMT307	HERG	Homo sapiens	IC50: 7244.36 (nM), Ref: 21185626
TCMC1982	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 960 (nM), Ref: 24328302
TCMC1982	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 910 (nM), Ref: 24328302
TCMC1982	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 5090 (nM), Ref: 24328302
TCMC1982	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 3320 (nM), Ref: 24328302
TCMC1982	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 5390 (nM), Ref: 24328302
TCMC1982	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 280 (nM), Ref: 25060641 IC50: 3500 (nM), Ref: 27162124
TCMC1982	TCMT793	Liver glycogen phosphorylase	Homo sapiens	IC50: 4800 (nM), Ref: 25092521
TCMC1982	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2110 (nM), Ref: 22328583
TCMC1982	TCMT217	Cytochrome P450 2C8	Homo sapiens	IC50: 1390 (nM), Ref: 22328583
TCMC11	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 800 (nM), Ref: 15679319 Ki: 54 (nM), Ref: 16248836
TCMC1982	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 8900 (nM), Ref: 26322379
TCMC1724	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 41 (nM), Ref: 10741545 Ki: 33 (nM), Ref: 14643346 Ki: 33 (nM), Ref: 17149859 Ki: 33 (nM), Ref: 17149858 Ki: 76 (nM), Ref: 17407276 IC50: 138 (nM), Ref: 17388627 IC50: 138 (nM), Ref: 17451272 IC50: 138 (nM), Ref: 18039010 Ki: 33 (nM), Ref: 18313920 Ki: 120 (nM), Ref: 19027293 IC50: 138 (nM), Ref: 16989522 Ki: 51 (nM), Ref: 20055417 Ki: 38 (nM), Ref: 21482470 Ki: 21.38 (nM), Ref: 19527931 Ki: 103 (nM), Ref: 25062506 Ki: 1516 (nM), Ref: 25268943 Ki: 30 (nM), Ref: 26035635 Ki: 103 (nM), Ref: 10.1039/C5MD00414D
TCMC1724	TCMT117	Kappa opioid receptor	Homo sapiens	Ki: 1.2 (nM), Ref: 10741545 Ki: 9.2 (nM), Ref: 17149859 Ki: 9.2 (nM), Ref: 17149858 Ki: 1.1 (nM), Ref: 17407276 IC50: 320 (nM), Ref: 17407276 Ki: 9.2 (nM), Ref: 18313920 Ki: 1.2 (nM), Ref: 19027293 Ki: 3 (nM), Ref: 20055417 Ki: 14.7 (nM), Ref: 20441176 Ki: 0.25 (nM), Ref: 21482470 Ki: 4.467 (nM), Ref: 19527931 Ki: 362 (nM), Ref: 25268943 Ki: 15 (nM), Ref: 10.1039/C5MD00414D
TCMC1724	TCMT116	Mu opioid receptor	Homo sapiens	IC50: 7.3 (nM), Ref: 14643346 Ki: 3.7 (nM), Ref: 17149859 IC50: 7.3 (nM), Ref: 17149859 Ki: 3.7 (nM), Ref: 17149858 IC50: 7.3 (nM), Ref: 17149858 Ki: 0.79 (nM), Ref: 17407276 IC50: 23 (nM), Ref: 17407276 Ki: 3.7 (nM), Ref: 18313920 IC50: 7.3 (nM), Ref: 18313920 Ki: 0.66 (nM), Ref: 19027293 Ki: 0.98 (nM), Ref: 20055417 Ki: 0.23 (nM), Ref: 21482470 Ki: 0.5623 (nM), Ref: 19527931 IC50: 1.87 (nM), Ref: 24171469 Ki: 2.3 (nM), Ref: 25062506 Ki: 354 (nM), Ref: 25268943 Ki: 1.148 (nM), Ref: 26632862 Ki: 1.259 (nM), Ref: 26632862 Ki: 2.3 (nM), Ref: 10.1039/C5MD00414D
TCMC1724	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.6 (nM), Ref: 16250647
TCMC1763	TCMT309	Solute carrier family 22 member 2	Homo sapiens	IC50: 2600 (nM), Ref: 23241029
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC264	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 105 (nM), Ref: 23332346
TCMC264	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 6.6 (nM), Ref: 23332346
TCMC22	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 1000 (nM), Ref: 15679319 Ki: 177 (nM), Ref: 16248836
TCMC930	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 459 (nM), Ref: 17616524
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC846	TCMT207	Beta-secretase 1	Homo sapiens	Ki: 6200 (nM), Ref: 22222157
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC1140	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 440 (nM), Ref: 15679319
TCMC1600	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 3.96 (nM), Ref: 12372519 Ki: 0.88 (nM), Ref: 16392810 Ki: 1.1 (nM), Ref: 16913723 Ki: 1.1 (nM), Ref: 17887741 Ki: 4 (nM), Ref: 17616524 Ki: 2.55 (nM), Ref: 19627147 Ki: 2.55 (nM), Ref: 21684752 Ki: 2.6 (nM), Ref: 21570305 Ki: 2.6 (nM), Ref: 22341895 Ki: 2.2 (nM), Ref: 24900459 Ki: 0.88 (nM), Ref: 22439881 IC50: 4.3 (nM), Ref: 22995061 Ki: 2.6 (nM), Ref: 23618710 Ki: 2.6 (nM), Ref: 23880358 IC50: 2.5 (nM), Ref: 24171469 Ki: 5.2 (nM), Ref: 25062506 Ki: 2.6 (nM), Ref: 25599950 Ki: 22 (nM), Ref: 25494650 IC50: 6.3 (nM), Ref: 26789491 Ki: 0.53 (nM), Ref: 26390077 Ki: 5.2 (nM), Ref: 10.1039/C5MD00414D
TCMC1600	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 140 (nM), Ref: 16392810 Ki: 140 (nM), Ref: 16913723 Ki: 140 (nM), Ref: 17887741 Ki: 605 (nM), Ref: 22341895 Ki: 140 (nM), Ref: 22439881 Ki: 605 (nM), Ref: 23618710 Ki: 605 (nM), Ref: 23880358 Ki: 605 (nM), Ref: 25599950
TCMC1600	TCMT117	Kappa opioid receptor	Homo sapiens	Ki: 24 (nM), Ref: 16392810 Ki: 46.9 (nM), Ref: 16913723 Ki: 46.9 (nM), Ref: 17887741 Ki: 6.9 (nM), Ref: 19932964 Ki: 299 (nM), Ref: 22341895 Ki: 24 (nM), Ref: 22439881 Ki: 60.9 (nM), Ref: 23419026 Ki: 299 (nM), Ref: 23618710 Ki: 299 (nM), Ref: 23880358 Ki: 299 (nM), Ref: 25599950 Ki: 120 (nM), Ref: 26390077
TCMC755	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	Ki: 600 (nM), Ref: 21739938
TCMC755	TCMT81	Arachidonate 12-lipoxygenase	Homo sapiens	Ki: 1600 (nM), Ref: 21739938
TCMC755	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC755	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 4400 (nM), Ref: 21030469 IC50: 7000 (nM), Ref: 21030469
TCMC755	TCMT384	G protein-coupled receptor kinase 6	Homo sapiens	IC50: 8700 (nM), Ref:
TCMC1329	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2710 (nM), Ref: 26275107
TCMC1723	TCMT117	Kappa opioid receptor	Homo sapiens	Ki: 0.38 (nM), Ref: 19027293 Ki: 2 (nM), Ref: 26390077
TCMC1723	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 120 (nM), Ref: 19027293
TCMC1723	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 0.19 (nM), Ref: 19027293 Ki: 0.36 (nM), Ref: 26390077
TCMC1870	TCMT781	Cytochrome P450 2E1	Homo sapiens	Ki: 9980 (nM), Ref: 16248836
TCMC1870	TCMT683	Macrophage migration inhibitory factor	Homo sapiens	IC50: 1600 (nM), Ref: 25743213
TCMC1870	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1700 (nM), Ref: 22696418
TCMC1870	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 3800 (nM), Ref: 22696418
TCMC1774	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 20674354 Ki: 3100 (nM), Ref: 21282059 Ki: 3400 (nM), Ref: 22137345
TCMC1774	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9300 (nM), Ref: 22137345
TCMC38	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 529 (nM), Ref: 23332346
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC732	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 5900 (nM), Ref: 21561086
TCMC1203	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 8000 (nM), Ref: 10.1039/C4MD00086B
TCMC28	TCMT853	Sigma opioid receptor	Homo sapiens	Ki: 36 (nM), Ref: 24617836 IC50: 8.24 (nM), Ref: 26717207 IC50: 7.59 (nM), Ref: 26717207
TCMC20	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 1100 (nM), Ref: 15679319
TCMC1977	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 7410 (nM), Ref: 21669522
TCMC1977	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 540 (nM), Ref: 21669522
TCMC1977	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 520 (nM), Ref: 21669522
TCMC136	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 830 (nM), Ref: 15679319
TCMC135	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 7400 (nM), Ref: 15679319
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC778	TCMT683	Macrophage migration inhibitory factor	Homo sapiens	IC50: 540 (nM), Ref: 25743213 IC50: 530 (nM), Ref: 25743213
TCMC1657	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 1.585 (nM), Ref: 26632862
TCMC1048	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 9500 (nM), Ref: 15679319 Ki: 142 (nM), Ref: 16248836
TCMC234	TCMT615	Sentrin-specific protease 8	Homo sapiens	IC50: 5470 (nM), Ref:
TCMC234	TCMT616	Sentrin-specific protease 7	Homo sapiens	IC50: 4630 (nM), Ref:
TCMC234	TCMT617	Sentrin-specific protease 6	Homo sapiens	IC50: 1860 (nM), Ref:
TCMC90	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2400 (nM), Ref: 14592472
TCMC929	TCMT116	Mu opioid receptor	Homo sapiens	Ki: 6300 (nM), Ref: 17616524
TCMC123	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 8800 (nM), Ref: 10978218
TCMC2180	TCMT302	HMG-CoA reductase	Homo sapiens	IC50: 5860 (nM), Ref: 25311563 IC50: 36.31 (nM), Ref: 25311563
TCMC265	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 91 (nM), Ref: 23332346
TCMC265	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 4.5 (nM), Ref: 23332346
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354
TCMC770	TCMT588	D-amino-acid oxidase	Homo sapiens	Ki: 7000 (nM), Ref: 23391306 IC50: 2089.3 (nM), Ref: 23631755 Ki: 2000 (nM), Ref: 23631755
TCMC998	TCMT154	Protein kinase C delta	Homo sapiens	Ki: 9.7 (nM), Ref: 23582444
TCMC1343	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 90 (nM), Ref: 18501600 Ki: 90 (nM), Ref: 18579385
TCMC1343	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7800 (nM), Ref: 18579385
TCMC1343	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8200 (nM), Ref: 18579385
TCMC1857	TCMT853	Sigma opioid receptor	Homo sapiens	Ki: 36 (nM), Ref: 27156565

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1851	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28 (ug/ml), Ref: 9461665
TCMC1429	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 16.77 (ug/ml), Ref: 20116898
TCMC2124	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 50 (ug/ml), Ref: 1710653
TCMC1982	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 17.65 (ug/ml), Ref: 20116898
TCMC1866	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC1329	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 13.9 (ug/ml), Ref: 20116898
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1203	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28.5 (ug/ml), Ref: 9461665
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1957	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC2370	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 7.8 (ug/ml), Ref: 15043439
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC1429	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 7.93 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2444	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 5.8 (ug/ml), Ref: 8786363 IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 5.8 (ug/ml), Ref: 8786363 IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 25372601
TCMC2454	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 19.6 (ug/ml), Ref: 10425115
TCMC1113	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 15863332
TCMC1102	TCMT1246	Escherichia coli	Escherichia coli	MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.103 (ug/ml), Ref: 11374952 IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 0.103 (ug/ml), Ref: 11374952 IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 5.5 (ug/ml), Ref: 12502337
TCMC1982	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812 MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 50 (ug/ml), Ref: 12762812
TCMC1982	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 29.5 (ug/ml), Ref: 12398543 IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 64 (ug/ml), Ref: 20655215 MIC: 64 (ug/ml), Ref: 21534606
TCMC1982	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 6 (ug/ml), Ref: 17394331
TCMC1982	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550	TCMT1393	Vibrio sp.	Vibrio sp.	MIC: 15 (ug/ml), Ref: 21865038
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC2565	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7 (ug/ml), Ref: 17845001
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC924	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC2576	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.24 (ug/ml), Ref: 8786363 IC50: 1.68 (ug/ml), Ref: 8786363
TCMC2576	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.24 (ug/ml), Ref: 8786363 IC50: 1.68 (ug/ml), Ref: 8786363
TCMC915	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 25791674
TCMC915	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC755	TCMT1251	Candida albicans	Candida albicans	IC50: 6 (ug/ml), Ref: 12502337
TCMC755	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC755	TCMT1249	Dengue virus 2	Dengue virus 2	IC50: 6.46 (ug/ml), Ref: 25564380
TCMC1329	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC2596	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 17845001
TCMC1238	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC2040	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.03 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC732	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 9 (ug/ml), Ref: 9748372
TCMC1203	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 22.6 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2035	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC1977	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 62.5 (ug/ml), Ref: 19232493
TCMC1977	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 19232493
TCMC2667	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 15104489 MIC: 100 (ug/ml), Ref: 20542692
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC2044	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 15 (ug/ml), Ref: 9644074 MIC: 15 (ug/ml), Ref: 8904847
TCMC2044	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 15 (ug/ml), Ref: 8904847
TCMC2044	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC90: 16 (ug/ml), Ref: 23127490 MIC90: 8 (ug/ml), Ref: 23127490 MIC: 16 (ug/ml), Ref: 23314053 MIC: 8 (ug/ml), Ref: 23314053
TCMC2044	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC90: 2 (ug/ml), Ref: 23127490 MIC: 2 (ug/ml), Ref: 23314053 MBC: 0.034 (nM), Ref: 22182580
TCMC2815	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 1517735
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001
TCMC1113	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 16 (nM), Ref: 17263522
TCMC1982	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 22 (nM), Ref: 17263522
TCMC2338	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 8.8 (nM), Ref: 17503850
TCMC2514	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 8.9 (nM), Ref: 17503850
TCMC2542	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 8.8 (nM), Ref: 17503850
TCMC2044	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MBC: 0.034 (nM), Ref: 22182580