Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC1372	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2330 (nM), Ref: 22245047
TCMC1372	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 3630 (nM), Ref: 22245047
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC244	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 7900 (nM), Ref: 15916432
TCMC244	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 8300 (nM), Ref: 15658857 IC50: 8298.51 (nM), Ref: 19110342
TCMC2052	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 9110 (nM), Ref: 22892213
TCMC2052	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8720 (nM), Ref: 22892213
TCMC2052	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 8430 (nM), Ref: 22892213
TCMC2052	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5930 (nM), Ref: 22892213
TCMC2052	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 780 (nM), Ref: 22892213
TCMC920	TCMT112	Adenosine A3 receptor	Homo sapiens	Ki: 1720 (nM), Ref: 8576921
TCMC1411	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1261 (nM), Ref: 20696580
TCMC1411	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 56 (nM), Ref: 20696580
TCMC1411	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 17 (nM), Ref: 20696580
TCMC1411	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 212.9 (nM), Ref: 26498393
TCMC1411	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.4 (nM), Ref: 26498393
TCMC1411	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 54.9 (nM), Ref: 26498393 Ki: 220 (nM), Ref: 26498393
TCMC1411	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 440 (nM), Ref: 26498393
TCMC949	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 19911821
TCMC949	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 48 (nM), Ref: 19911821
TCMC949	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9100 (nM), Ref: 19911821
TCMC949	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3300 (nM), Ref: 19911821
TCMC949	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 2000 (nM), Ref: 19911821
TCMC949	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 5200 (nM), Ref: 19911821
TCMC949	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9400 (nM), Ref: 19911821
TCMC949	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 6800 (nM), Ref: 19911821
TCMC949	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 5600 (nM), Ref: 19911821
TCMC949	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 19911821 Ki: 3100 (nM), Ref: 21067924 Ki: 3100 (nM), Ref: 22137345 Ki: 3100 (nM), Ref: 22077347 Ki: 3100 (nM), Ref: 22365761 Ki: 3100 (nM), Ref: 22377674 Ki: 3100 (nM), Ref: 23241068 Ki: 3100 (nM), Ref: 22892213 Ki: 3100 (nM), Ref: 26688270
TCMC949	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 21067924 Ki: 9200 (nM), Ref: 22137345 Ki: 9200 (nM), Ref: 22077347 Ki: 9200 (nM), Ref: 22365761 Ki: 9200 (nM), Ref: 22377674 Ki: 9200 (nM), Ref: 23241068 Ki: 9200 (nM), Ref: 22892213 Ki: 9200 (nM), Ref: 26688270
TCMC1844	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 8400 (nM), Ref: 26035635
TCMC1844	TCMT510	Stem cell growth factor receptor	Homo sapiens	IC50: 600 (nM), Ref: 26807861 IC50: 1500 (nM), Ref: 26807861
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC2003	TCMT82	Estrogen receptor alpha	Homo sapiens	Ki: 785 (nM), Ref: 15634023
TCMC2003	TCMT164	Cyclooxygenase-1	Homo sapiens	IC50: 2840 (nM), Ref: 16814546 IC50: 4120 (nM), Ref: 18063374 IC50: 625 (nM), Ref:
TCMC2003	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 996 (nM), Ref: 17604631 IC50: 750 (nM), Ref: 20527891 IC50: 996 (nM), Ref: 26850006
TCMC2003	TCMT329	Quinone reductase 2	Homo sapiens	IC50: 960 (nM), Ref: 19265439 IC50: 450 (nM), Ref: 20036559 IC50: 450 (nM), Ref: 20356739 IC50: 960 (nM), Ref: 21261296 IC50: 6900 (nM), Ref: 23953689 Ki: 88 (nM), Ref: 23953689 IC50: 1400 (nM), Ref: 26854376 IC50: 913 (nM), Ref: 26854376
TCMC2003	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2210 (nM), Ref: 20674354
TCMC2003	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2770 (nM), Ref: 20674354
TCMC2003	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 9090 (nM), Ref: 20674354
TCMC2003	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4470 (nM), Ref: 20674354
TCMC2003	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4750 (nM), Ref: 20674354
TCMC2003	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4640 (nM), Ref: 20674354
TCMC2003	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8070 (nM), Ref: 20674354
TCMC2003	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4350 (nM), Ref: 20674354
TCMC2003	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 810 (nM), Ref: 20674354
TCMC2003	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 950 (nM), Ref: 20674354
TCMC2003	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4090 (nM), Ref: 20674354
TCMC2003	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 830 (nM), Ref: 20674354
TCMC2003	TCMT729	PI3-kinase p110-alpha subunit	Homo sapiens	IC50: 250 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT730	PI3-kinase p110-beta subunit	Homo sapiens	IC50: 500 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4100 (nM), Ref: 27190601 IC50: 2600 (nM), Ref: 27190601
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1409	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 5250 (nM), Ref: IC50: 8960 (nM), Ref:
TCMC1409	TCMT223	Aldose reductase	Homo sapiens	IC50: 4500 (nM), Ref: 22261024
TCMC1409	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 6211.2 (nM), Ref: 26498393 Ki: 410 (nM), Ref: 26498393
TCMC1409	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 75.7 (nM), Ref: 26498393
TCMC1409	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3.8 (nM), Ref: 26498393
TCMC1409	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.1 (nM), Ref: 26498393 Ki: 170 (nM), Ref: 26498393
TCMC1982	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302
TCMC1982	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208
TCMC1982	TCMT223	Aldose reductase	Homo sapiens	IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999
TCMC405	TCMT506	Protein tyrosine kinase 2 beta	Homo sapiens	IC50: 2324 (nM), Ref:
TCMC1982	TCMT44	Glyoxalase I	Homo sapiens	IC50: 3200 (nM), Ref: 18258440
TCMC1982	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 1540 (nM), Ref: 18533708
TCMC1982	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7890 (nM), Ref: 20185318
TCMC1982	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8100 (nM), Ref: 20185318
TCMC1982	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2540 (nM), Ref: 20185318
TCMC1982	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2680 (nM), Ref: 20185318
TCMC1982	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6810 (nM), Ref: 20185318
TCMC1982	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6170 (nM), Ref: 20185318
TCMC1982	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4840 (nM), Ref: 20185318
TCMC1982	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7000 (nM), Ref: 20185318
TCMC1982	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9390 (nM), Ref: 20185318
TCMC1982	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 5410 (nM), Ref: 20185318
TCMC1982	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 12 (nM), Ref: 20413308
TCMC1982	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 4097 (nM), Ref: 20696580 IC50: 1550 (nM), Ref: 22328583
TCMC1982	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1191 (nM), Ref: 20696580
TCMC1982	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 77 (nM), Ref: 20696580
TCMC1982	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 6680 (nM), Ref: 22658537
TCMC1982	TCMT320	Matrix metalloproteinase 3	Homo sapiens	IC50: 5570 (nM), Ref: 22658537
TCMC1982	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 1610 (nM), Ref: 22658537
TCMC1982	TCMT322	Matrix metalloproteinase 13	Homo sapiens	IC50: 8460 (nM), Ref: 22658537
TCMC1982	TCMT422	CaM kinase II beta	Homo sapiens	IC50: 3000 (nM), Ref: 21798748
TCMC1982	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y IC50: 6500 (nM), Ref: 26003344
TCMC1982	TCMT784	Vasopressin V2 receptor	Homo sapiens	IC50: 7000 (nM), Ref: 23437772 IC50: 6309.57 (nM), Ref: 23437772
TCMC1982	TCMT785	Interleukin-8 receptor A	Homo sapiens	IC50: 4500 (nM), Ref: 23437772 IC50: 5011.87 (nM), Ref: 23437772
TCMC1982	TCMT786	C-C chemokine receptor type 4	Homo sapiens	IC50: 10000 (nM), Ref: 23437772
TCMC1982	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 590 (nM), Ref: 23411073
TCMC1982	TCMT601	Thrombin	Homo sapiens	IC50: 1500 (nM), Ref: 24610996
TCMC1982	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 280 (nM), Ref: 24328302
TCMC1982	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 120 (nM), Ref: 24328302
TCMC1982	TCMT791	Protein kinase N1	Homo sapiens	IC50: 5800 (nM), Ref: 24328302
TCMC1982	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 5750 (nM), Ref: 24328302
TCMC1982	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 4230 (nM), Ref: 24328302
TCMC1982	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 5730 (nM), Ref: 24328302
TCMC1982	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 24328302
TCMC1982	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 300 (nM), Ref: 24328302
TCMC1982	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 1200 (nM), Ref: 24328302
TCMC1982	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 960 (nM), Ref: 24328302
TCMC1982	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 910 (nM), Ref: 24328302
TCMC1982	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 5090 (nM), Ref: 24328302
TCMC1982	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 3320 (nM), Ref: 24328302
TCMC1982	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 5390 (nM), Ref: 24328302
TCMC1982	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 280 (nM), Ref: 25060641 IC50: 3500 (nM), Ref: 27162124
TCMC1982	TCMT793	Liver glycogen phosphorylase	Homo sapiens	IC50: 4800 (nM), Ref: 25092521
TCMC1982	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2110 (nM), Ref: 22328583
TCMC1982	TCMT217	Cytochrome P450 2C8	Homo sapiens	IC50: 1390 (nM), Ref: 22328583
TCMC1982	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 8900 (nM), Ref: 26322379
TCMC245	TCMT329	Quinone reductase 2	Homo sapiens	IC50: 3300 (nM), Ref: 21074425
TCMC469	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 100 (nM), Ref: 22921742
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC418	TCMT223	Aldose reductase	Homo sapiens	IC50: 78 (nM), Ref: 22236472
TCMC418	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 240 (nM), Ref: 22236472
TCMC418	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4700 (nM), Ref: 22921742
TCMC726	TCMT167	Aldo-keto-reductase family 1 member C3	Homo sapiens	IC50: 1000 (nM), Ref: 22506594 Ki: 680 (nM), Ref: 22506594 Ki: 680 (nM), Ref: 22506594
TCMC2204	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 482 (nM), Ref: 21067924 Ki: 478 (nM), Ref: 22077347 Ki: 480 (nM), Ref: 26688270
TCMC2204	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 754 (nM), Ref: 22077347 Ki: 750 (nM), Ref: 26688270
TCMC1105	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 2000 (nM), Ref: 19414254
TCMC1105	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2500 (nM), Ref: 27173800
TCMC1319	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9700 (nM), Ref: 19911821
TCMC1319	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9000 (nM), Ref: 19911821
TCMC1319	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9800 (nM), Ref: 19911821
TCMC1319	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 2400 (nM), Ref: 19911821
TCMC1319	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5500 (nM), Ref: 19911821
TCMC1319	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5100 (nM), Ref: 19911821
TCMC1319	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 8300 (nM), Ref: 19911821
TCMC1319	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5900 (nM), Ref: 19911821
TCMC1356	TCMT223	Aldose reductase	Homo sapiens	IC50: 3000 (nM), Ref: 22261024
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1701	TCMT158	Epoxide hydratase	Homo sapiens	Ki: 600 (nM), Ref: 19128055 IC50: 2200 (nM), Ref: 25052206

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2257	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 15.46 (ug/ml), Ref: 20116898
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC1982	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 17.65 (ug/ml), Ref: 20116898
TCMC469	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 5.4 (ug/ml), Ref: 16643034
TCMC1356	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 64.6 (ug/ml), Ref: 9461665
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC920	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 31.25 (ug/ml), Ref: 6677714
TCMC920	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 62.5 (ug/ml), Ref: 6677714
TCMC920	TCMT1246	Escherichia coli	Escherichia coli	MIC: 45 (ug/ml), Ref: 6677714
TCMC920	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 45 (ug/ml), Ref: 6677714
TCMC920	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 31.25 (ug/ml), Ref: 6677714
TCMC2257	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 37.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 59.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC2003	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1251	Candida albicans	Candida albicans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1246	Escherichia coli	Escherichia coli	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12036362
TCMC2003	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753
TCMC2003	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 25 (ug/ml), Ref: 20022753
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC1409	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 94 (ug/ml), Ref: 15104489
TCMC1409	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 5.9 (ug/ml), Ref: 15104496
TCMC1409	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 23.4 (ug/ml), Ref: 15104496
TCMC1409	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 12762812
TCMC1409	TCMT1443	Leishmania amazonensis	Leishmania amazonensis	IC50: 0.78 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC887	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 62.5 (ug/ml), Ref: 10395496
TCMC2493	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20004575 MIC: 1.56 (ug/ml), Ref: 22280816
TCMC1982	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812 MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 50 (ug/ml), Ref: 12762812
TCMC1982	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 29.5 (ug/ml), Ref: 12398543 IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 64 (ug/ml), Ref: 20655215 MIC: 64 (ug/ml), Ref: 21534606
TCMC1982	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 6 (ug/ml), Ref: 17394331
TCMC1982	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1767	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 60 (ug/ml), Ref: 20384293
TCMC1767	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550	TCMT1393	Vibrio sp.	Vibrio sp.	MIC: 15 (ug/ml), Ref: 21865038
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC924	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC2182	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC2595	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 50 (ug/ml), Ref: 25462220
TCMC1105	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 23534483
TCMC1105	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1 (ug/ml), Ref: 23534483
TCMC1105	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 23534483 MIC: 4 (ug/ml), Ref: 23534483
TCMC1238	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC2166	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 50 (ug/ml), Ref: 8864235
TCMC2166	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1321	Staphylococcus hominis	Staphylococcus hominis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906 MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1209	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1343	Staphylococcus simulans	Staphylococcus simulans	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1344	Staphylococcus sciuri	Staphylococcus sciuri	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC1356	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 32 (ug/ml), Ref: 21534606
TCMC1356	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 16 (ug/ml), Ref: 21534606
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2014	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 10 (ug/ml), Ref: 17220400
TCMC1578	TCMT1408	Colletotrichum gloeosporioides	Colletotrichum gloeosporioides	IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578	TCMT1245	Phytophthora cactorum	Phytophthora cactorum	IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1738	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC2815	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 1517735
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001
TCMC1982	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 22 (nM), Ref: 17263522