Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1293	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2940 (nM), Ref: 19231207
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC1597	TCMT807	Solute carrier family 22 member 12	Homo sapiens	IC50: 2000 (nM), Ref: 17325024 Ki: 5740 (nM), Ref: 17325024
TCMC1597	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2927.18 (nM), Ref:
TCMC1597	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 2988.26 (nM), Ref:
TCMC1597	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 1600 (nM), Ref: 24900447
TCMC1597	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 1600 (nM), Ref: 26322379
TCMC1597	TCMT283	Receptor-type tyrosine-protein phosphatase S	Homo sapiens	IC50: 4300 (nM), Ref: 26602279
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC850	TCMT307	HERG	Homo sapiens	IC50: 4897.79 (nM), Ref: 21185626
TCMC850	TCMT707	Adenosine A2a receptor	Homo sapiens	Ki: 5011.87 (nM), Ref: 21661720 Ki: 9560 (nM), Ref: 23200243 Ki: 2480 (nM), Ref: 23200243
TCMC850	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 7250 (nM), Ref: 23791077
TCMC1115	TCMT860	Histone deacetylase 10	Homo sapiens	IC50: 8100 (nM), Ref: 24328302
TCMC1115	TCMT555	Histone deacetylase 6	Homo sapiens	IC50: 6500 (nM), Ref: 24328302
TCMC1115	TCMT691	Histone deacetylase 8	Homo sapiens	IC50: 2100 (nM), Ref: 24328302
TCMC1115	TCMT690	Histone deacetylase 3	Homo sapiens	IC50: 6900 (nM), Ref: 24328302
TCMC1115	TCMT556	Histone deacetylase 2	Homo sapiens	IC50: 9100 (nM), Ref: 24328302
TCMC1115	TCMT557	Histone deacetylase 1	Homo sapiens	IC50: 8800 (nM), Ref: 24328302
TCMC1115	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 390 (nM), Ref: 24328302
TCMC1115	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 490 (nM), Ref: 24328302
TCMC1115	TCMT791	Protein kinase N1	Homo sapiens	IC50: 9000 (nM), Ref: 24328302
TCMC1115	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 6310 (nM), Ref: 24328302
TCMC1115	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 4440 (nM), Ref: 24328302
TCMC1115	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 1850 (nM), Ref: 24328302
TCMC1115	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 3780 (nM), Ref: 24328302
TCMC1115	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 1120 (nM), Ref: 24328302
TCMC1115	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 150 (nM), Ref: 24328302
TCMC1115	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 800 (nM), Ref: 24328302
TCMC1115	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 220 (nM), Ref: 24328302
TCMC1115	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 7290 (nM), Ref: 24328302
TCMC1115	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 3770 (nM), Ref: 24328302
TCMC1115	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 250 (nM), Ref: 24328302
TCMC1115	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 4070 (nM), Ref: 24328302
TCMC49	TCMT651	Dopamine D3 receptor	Homo sapiens	Ki: 500 (nM), Ref: 24559070
TCMC49	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 5000 (nM), Ref: 24559070
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2417	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25760525 MIC: 32 (ug/ml), Ref: 25760525
TCMC2417	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 25760525
TCMC2478	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 0.1904 (ug/ml), Ref: 9644053
TCMC2478	TCMT1438	Plasmodium falciparum	Plasmodium falciparum NF54	IC50: 0.2709 (ug/ml), Ref: 9644053
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1936	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 14 (ug/ml), Ref: 10425115
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC2606	TCMT1248	Hepatitis C virus	Hepatitis C virus	IC50: 20 (ug/ml), Ref: 19904996
TCMC2633	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 100 (ug/ml), Ref: 10425115
TCMC2633	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 5.8 (ug/ml), Ref: 10425115
TCMC2642	TCMT1251	Candida albicans	Candida albicans	IC50: 3.5 (ug/ml), Ref: 12088427 MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 12088427 IC50: 2 (ug/ml), Ref: 12088427
TCMC2642	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 2 (ug/ml), Ref: 12088427 MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642	TCMT1355	Rhodococcus equi	Rhodococcus equi	MIC: 10 (ug/ml), Ref: 19639965
TCMC2642	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 12 (ug/ml), Ref: 19874044
TCMC2642	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC2642	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC2675	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 8.3 (ug/ml), Ref: 10425115
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2733	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 4 (ug/ml), Ref: 14698179
TCMC2734	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 15715470 MIC: 64 (ug/ml), Ref: MIC: 32 (ug/ml), Ref: 19179074
TCMC2735	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 8 (ug/ml), Ref: 15715470 MIC: 8 (ug/ml), Ref: 22194678 MIC: 8 (ug/ml), Ref: 19179074
TCMC2733	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 2 (ug/ml), Ref: 19179074 MIC: 4 (ug/ml), Ref: 16643039
TCMC2735	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17190457
TCMC2735	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 20405847
TCMC2733	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 4 (ug/ml), Ref: 12617583
TCMC2734	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 12617583
TCMC2734	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17438047
TCMC2735	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 17438047
TCMC2733	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 4 (ug/ml), Ref: 17438047
TCMC2772	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25856683 MIC: 8 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 16 (ug/ml), Ref: 15497933
TCMC2772	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 15679329
TCMC2772	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 18541727
TCMC2772	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref:
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915