Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1360	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 5900 (nM), Ref: 18778098
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1501	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 2100 (nM), Ref: 18042388 IC50: 340 (nM), Ref: 18778944
TCMC1399	TCMT223	Aldose reductase	Homo sapiens	IC50: 320 (nM), Ref: 22261024
TCMC1409	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 5250 (nM), Ref: IC50: 8960 (nM), Ref:
TCMC1409	TCMT223	Aldose reductase	Homo sapiens	IC50: 4500 (nM), Ref: 22261024
TCMC1409	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 6211.2 (nM), Ref: 26498393 Ki: 410 (nM), Ref: 26498393
TCMC1409	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 75.7 (nM), Ref: 26498393
TCMC1409	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3.8 (nM), Ref: 26498393
TCMC1409	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.1 (nM), Ref: 26498393 Ki: 170 (nM), Ref: 26498393
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1356	TCMT223	Aldose reductase	Homo sapiens	IC50: 3000 (nM), Ref: 22261024
TCMC2201	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 8700 (nM), Ref: 21332115

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1399	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1136	Neuraminidase	Influenza A virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1121	Sialidase	Clostridium perfringens	IC50: 11.28 (ug/ml), Ref: 21123068
TCMC1356	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 64.6 (ug/ml), Ref: 9461665
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC1399	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 62.5 (ug/ml), Ref: 18951808
TCMC1399	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.6 (ug/ml), Ref: 25137491
TCMC1409	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 94 (ug/ml), Ref: 15104489
TCMC1409	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 5.9 (ug/ml), Ref: 15104496
TCMC1409	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 23.4 (ug/ml), Ref: 15104496
TCMC1409	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 12762812
TCMC1409	TCMT1443	Leishmania amazonensis	Leishmania amazonensis	IC50: 0.78 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1356	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 32 (ug/ml), Ref: 21534606
TCMC1356	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 16 (ug/ml), Ref: 21534606