Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1871	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9200 (nM), Ref: 20185318 Ki: 9200 (nM), Ref: 20590092 Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9200 (nM), Ref: 23265898 Ki: 9200 (nM), Ref: 23010455 Ki: 9200 (nM), Ref: 24189056
TCMC1871	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8800 (nM), Ref: 20185318 Ki: 8800 (nM), Ref: 20590092 Ki: 8800 (nM), Ref: 20674354 Ki: 8800 (nM), Ref: 21282059 Ki: 8800 (nM), Ref: 23265898 Ki: 8800 (nM), Ref: 23010455 Ki: 8800 (nM), Ref: 24189056 Ki: 8800 (nM), Ref: 26520662
TCMC1871	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9500 (nM), Ref: 20185318 Ki: 9500 (nM), Ref: 20590092 Ki: 9500 (nM), Ref: 20674354 Ki: 9500 (nM), Ref: 23010455
TCMC1871	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 2700 (nM), Ref: 20185318 Ki: 2700 (nM), Ref: 20590092 Ki: 2700 (nM), Ref: 20674354 Ki: 2700 (nM), Ref: 23010455
TCMC1871	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 5500 (nM), Ref: 20185318 Ki: 5500 (nM), Ref: 20590092 Ki: 5500 (nM), Ref: 20674354 Ki: 5500 (nM), Ref: 21282059 Ki: 5500 (nM), Ref: 21332115 Ki: 5500 (nM), Ref: 23265898 Ki: 5500 (nM), Ref: 23265903 Ki: 5500 (nM), Ref: 23010455 Ki: 5500 (nM), Ref: 24189056 Ki: 5500 (nM), Ref: 26073005 Ki: 5500 (nM), Ref: 26520662
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC1429	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 2700 (nM), Ref: 17378609
TCMC1429	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 1050 (nM), Ref: 18533708
TCMC1429	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 360 (nM), Ref: 18533708
TCMC1429	TCMT187	Androgen Receptor	Homo sapiens	IC50: 9700 (nM), Ref: 19592245
TCMC1429	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 716 (nM), Ref: 20696580
TCMC1429	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 632 (nM), Ref: 20696580
TCMC1429	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 47 (nM), Ref: 20696580
TCMC1429	TCMT223	Aldose reductase	Homo sapiens	IC50: 10000 (nM), Ref: 22261024
TCMC1429	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 2320 (nM), Ref: 23411073
TCMC1429	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 9640 (nM), Ref: 23656512
TCMC1429	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 10000 (nM), Ref: 26322379
TCMC1429	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9525.7 (nM), Ref: 26498393
TCMC1429	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 25 (nM), Ref: 26498393
TCMC1429	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 145.9 (nM), Ref: 26498393
TCMC1429	TCMT159	Tyrosinase	Homo sapiens	IC50: 1000 (nM), Ref: 26841168
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC1396	TCMT689	Protein-glutamine gamma-glutamyltransferase	Homo sapiens	IC50: 8000 (nM), Ref: 21215619
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC706	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 9510 (nM), Ref: 19028102
TCMC1986	TCMT223	Aldose reductase	Homo sapiens	IC50: 150 (nM), Ref: 18165015 IC50: 2000 (nM), Ref: 22261024
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302
TCMC1982	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208
TCMC1982	TCMT223	Aldose reductase	Homo sapiens	IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999
TCMC1982	TCMT44	Glyoxalase I	Homo sapiens	IC50: 3200 (nM), Ref: 18258440
TCMC1982	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 1540 (nM), Ref: 18533708
TCMC1982	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7890 (nM), Ref: 20185318
TCMC1982	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8100 (nM), Ref: 20185318
TCMC1982	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2540 (nM), Ref: 20185318
TCMC1982	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2680 (nM), Ref: 20185318
TCMC1982	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6810 (nM), Ref: 20185318
TCMC1982	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6170 (nM), Ref: 20185318
TCMC1982	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4840 (nM), Ref: 20185318
TCMC1982	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7000 (nM), Ref: 20185318
TCMC1982	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9390 (nM), Ref: 20185318
TCMC1982	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 5410 (nM), Ref: 20185318
TCMC1982	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 12 (nM), Ref: 20413308
TCMC1982	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 4097 (nM), Ref: 20696580 IC50: 1550 (nM), Ref: 22328583
TCMC1982	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1191 (nM), Ref: 20696580
TCMC1982	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 77 (nM), Ref: 20696580
TCMC1982	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 6680 (nM), Ref: 22658537
TCMC1982	TCMT320	Matrix metalloproteinase 3	Homo sapiens	IC50: 5570 (nM), Ref: 22658537
TCMC1982	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 1610 (nM), Ref: 22658537
TCMC1982	TCMT322	Matrix metalloproteinase 13	Homo sapiens	IC50: 8460 (nM), Ref: 22658537
TCMC1982	TCMT422	CaM kinase II beta	Homo sapiens	IC50: 3000 (nM), Ref: 21798748
TCMC1982	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y IC50: 6500 (nM), Ref: 26003344
TCMC1982	TCMT784	Vasopressin V2 receptor	Homo sapiens	IC50: 7000 (nM), Ref: 23437772 IC50: 6309.57 (nM), Ref: 23437772
TCMC1982	TCMT785	Interleukin-8 receptor A	Homo sapiens	IC50: 4500 (nM), Ref: 23437772 IC50: 5011.87 (nM), Ref: 23437772
TCMC1982	TCMT786	C-C chemokine receptor type 4	Homo sapiens	IC50: 10000 (nM), Ref: 23437772
TCMC1982	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 590 (nM), Ref: 23411073
TCMC1982	TCMT601	Thrombin	Homo sapiens	IC50: 1500 (nM), Ref: 24610996
TCMC1982	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 280 (nM), Ref: 24328302
TCMC1982	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 120 (nM), Ref: 24328302
TCMC1982	TCMT791	Protein kinase N1	Homo sapiens	IC50: 5800 (nM), Ref: 24328302
TCMC1982	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 5750 (nM), Ref: 24328302
TCMC1982	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 4230 (nM), Ref: 24328302
TCMC1982	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 5730 (nM), Ref: 24328302
TCMC1982	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 24328302
TCMC1982	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 300 (nM), Ref: 24328302
TCMC1982	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 1200 (nM), Ref: 24328302
TCMC1982	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 960 (nM), Ref: 24328302
TCMC1982	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 910 (nM), Ref: 24328302
TCMC1982	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 5090 (nM), Ref: 24328302
TCMC1982	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 3320 (nM), Ref: 24328302
TCMC1982	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 5390 (nM), Ref: 24328302
TCMC1982	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 280 (nM), Ref: 25060641 IC50: 3500 (nM), Ref: 27162124
TCMC1982	TCMT793	Liver glycogen phosphorylase	Homo sapiens	IC50: 4800 (nM), Ref: 25092521
TCMC1982	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2110 (nM), Ref: 22328583
TCMC1982	TCMT217	Cytochrome P450 2C8	Homo sapiens	IC50: 1390 (nM), Ref: 22328583
TCMC1982	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 8900 (nM), Ref: 26322379
TCMC880	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9910 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 20185318 Ki: 9900 (nM), Ref: 22245047 Ki: 9900 (nM), Ref: 26073005 Ki: 9900 (nM), Ref: 26520662
TCMC880	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4200 (nM), Ref: 18579385 Ki: 4200 (nM), Ref: 20185318
TCMC880	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 18579385 Ki: 8900 (nM), Ref: 20185318
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC2196	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282
TCMC2196	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 150 (nM), Ref: 22819942
TCMC2196	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC1774	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3100 (nM), Ref: 20674354 Ki: 3100 (nM), Ref: 21282059 Ki: 3400 (nM), Ref: 22137345
TCMC1774	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9300 (nM), Ref: 22137345
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1377	TCMT186	Monoamine oxidase B	Homo sapiens	Ki: 3000 (nM), Ref: 16137882 Ki: 3000 (nM), Ref: 19342233 IC50: 7943.28 (nM), Ref: 20934874 Ki: 5340 (nM), Ref: 21134756 Ki: 3000 (nM), Ref: 21778064 Ki: 2000 (nM), Ref: 24140951
TCMC1377	TCMT208	Monoamine oxidase A	Homo sapiens	Ki: 8380 (nM), Ref: 21134756
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC2238	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 9000 (nM), Ref: 23791077
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1237	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7300 (nM), Ref: 22668600
TCMC1237	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6600 (nM), Ref: 22668600
TCMC1237	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4100 (nM), Ref: 22668600
TCMC1237	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4200 (nM), Ref: 22668600
TCMC710	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554
TCMC710	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 710 (nM), Ref: 18533708
TCMC710	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 800 (nM), Ref: 19414254
TCMC710	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5200 (nM), Ref: 19592245
TCMC710	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 795 (nM), Ref: 20696580
TCMC710	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 427 (nM), Ref: 20696580
TCMC710	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC710	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1450 (nM), Ref: 23411073
TCMC710	TCMT128	Tankyrase-2	Homo sapiens	IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272
TCMC710	TCMT129	Tankyrase-1	Homo sapiens	IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272
TCMC710	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844
TCMC710	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431
TCMC666	TCMT158	Epoxide hydratase	Homo sapiens	Ki: 2000 (nM), Ref: 26372074
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354
TCMC770	TCMT588	D-amino-acid oxidase	Homo sapiens	Ki: 7000 (nM), Ref: 23391306 IC50: 2089.3 (nM), Ref: 23631755 Ki: 2000 (nM), Ref: 23631755

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1429	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 16.77 (ug/ml), Ref: 20116898
TCMC1986	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 75.2 (ug/ml), Ref: 9461665
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC1982	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 17.65 (ug/ml), Ref: 20116898
TCMC710	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 8.54 (ug/ml), Ref: 20116898
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC1429	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 7.93 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2402	TCMT1251	Candida albicans	Candida albicans	MIC: 31.25 (ug/ml), Ref: 8254344
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1986	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 17.7 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC1982	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812 MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 50 (ug/ml), Ref: 12762812
TCMC1982	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 29.5 (ug/ml), Ref: 12398543 IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 64 (ug/ml), Ref: 20655215 MIC: 64 (ug/ml), Ref: 21534606
TCMC1982	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 6 (ug/ml), Ref: 17394331
TCMC1982	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC612	TCMT1207	Legionella pneumophila	Legionella pneumophila	MIC: 0 (ug/ml), Ref: 21244021
TCMC2196	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 10 (ug/ml), Ref: 22819942 MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 1 (ug/ml), Ref: 23360475 MIC: 1 (ug/ml), Ref: 26253635
TCMC2196	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 6 (ug/ml), Ref: 26253635
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC2644	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2014	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 10 (ug/ml), Ref: 17220400
TCMC395	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC710	TCMT1246	Escherichia coli	Escherichia coli	MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC710	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC710	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001
TCMC1982	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 22 (nM), Ref: 17263522