Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC1372	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2330 (nM), Ref: 22245047
TCMC1372	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 3630 (nM), Ref: 22245047
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC244	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 7900 (nM), Ref: 15916432
TCMC244	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 8300 (nM), Ref: 15658857 IC50: 8298.51 (nM), Ref: 19110342
TCMC619	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 158.49 (nM), Ref: 18077164
TCMC619	TCMT291	Muscarinic acetylcholine receptor M3	Homo sapiens	Ki: 7079.46 (nM), Ref: 18077164
TCMC619	TCMT551	Muscarinic acetylcholine receptor M4	Homo sapiens	Ki: 8511.38 (nM), Ref: 18077164
TCMC619	TCMT290	Muscarinic acetylcholine receptor M5	Homo sapiens	Ki: 9772.37 (nM), Ref: 18077164
TCMC1871	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9200 (nM), Ref: 20185318 Ki: 9200 (nM), Ref: 20590092 Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9200 (nM), Ref: 23265898 Ki: 9200 (nM), Ref: 23010455 Ki: 9200 (nM), Ref: 24189056
TCMC1871	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8800 (nM), Ref: 20185318 Ki: 8800 (nM), Ref: 20590092 Ki: 8800 (nM), Ref: 20674354 Ki: 8800 (nM), Ref: 21282059 Ki: 8800 (nM), Ref: 23265898 Ki: 8800 (nM), Ref: 23010455 Ki: 8800 (nM), Ref: 24189056 Ki: 8800 (nM), Ref: 26520662
TCMC1871	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9500 (nM), Ref: 20185318 Ki: 9500 (nM), Ref: 20590092 Ki: 9500 (nM), Ref: 20674354 Ki: 9500 (nM), Ref: 23010455
TCMC1871	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 2700 (nM), Ref: 20185318 Ki: 2700 (nM), Ref: 20590092 Ki: 2700 (nM), Ref: 20674354 Ki: 2700 (nM), Ref: 23010455
TCMC1871	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 5500 (nM), Ref: 20185318 Ki: 5500 (nM), Ref: 20590092 Ki: 5500 (nM), Ref: 20674354 Ki: 5500 (nM), Ref: 21282059 Ki: 5500 (nM), Ref: 21332115 Ki: 5500 (nM), Ref: 23265898 Ki: 5500 (nM), Ref: 23265903 Ki: 5500 (nM), Ref: 23010455 Ki: 5500 (nM), Ref: 24189056 Ki: 5500 (nM), Ref: 26073005 Ki: 5500 (nM), Ref: 26520662
TCMC619	TCMT241	Neuronal acetylcholine receptor protein alpha-7 subunit	Homo sapiens	Ki: 7943.28 (nM), Ref: 21920761
TCMC1330	TCMT246	Histamine H4 receptor	Homo sapiens	Ki: 14.45 (nM), Ref: 14640553 Ki: 7.943 (nM), Ref: 15454206 Ki: 12.02 (nM), Ref: 18357976 Ki: 13.4 (nM), Ref: 18459760 Ki: 12.02 (nM), Ref: 20192225 Ki: 60 (nM), Ref: 20452213 Ki: 7.943 (nM), Ref: 21044842 Ki: 12.59 (nM), Ref: 21044842 Ki: 12.02 (nM), Ref: 21348462 Ki: 15.85 (nM), Ref: 22003888 Ki: 9 (nM), Ref: 22153663 Ki: 19.95 (nM), Ref: 10.1039/C2MD20212C Ki: 4.8 (nM), Ref: 25993395 Ki: 8 (nM), Ref: 25993395 Ki: 15.85 (nM), Ref: 10.1039/C5MD00022J
TCMC1330	TCMT242	Histamine H3 receptor	Homo sapiens	Ki: 5.2 (nM), Ref: 20384344 Ki: 10 (nM), Ref: 21044842 Ki: 11.75 (nM), Ref: 21348462 Ki: 6.31 (nM), Ref: 22003888 Ki: 16 (nM), Ref: 25993395
TCMC1330	TCMT245	Histamine H2 receptor	Homo sapiens	Ki: 5000 (nM), Ref: 25993395
TCMC1330	TCMT244	Histamine H1 receptor	Homo sapiens	Ki: 6000 (nM), Ref: 25993395
TCMC1293	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2940 (nM), Ref: 19231207
TCMC1786	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3900 (nM), Ref: 16580200 IC50: 7600 (nM), Ref: 18798681 IC50: 4200 (nM), Ref: 19702283 IC50: 3840 (nM), Ref: 22044245 IC50: 5600 (nM), Ref: 22690646 IC50: 9500 (nM), Ref: 21453996 Ki: 6000 (nM), Ref: 21453996 IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2600 (nM), Ref: 23357636 IC50: 1100 (nM), Ref: 23434422 IC50: 3020 (nM), Ref: 23942421 IC50: 2010 (nM), Ref: 24090912 IC50: 1900 (nM), Ref: 24684845 IC50: 3020 (nM), Ref: 25497963 IC50: 9500 (nM), Ref: 25264584 Ki: 6000 (nM), Ref: 25264584 IC50: 1030 (nM), Ref: 25595683 IC50: 1170 (nM), Ref: 25600405 IC50: 3020 (nM), Ref: 25872983 IC50: 1000 (nM), Ref: 26083682 IC50: 1536 (nM), Ref: 26100442 IC50: 700 (nM), Ref: 26115570 IC50: 700 (nM), Ref: 26253631 IC50: 1536 (nM), Ref: 26481657 IC50: 730 (nM), Ref: 26711144 IC50: 3020 (nM), Ref: 26774579 IC50: 1536 (nM), Ref: 27123900
TCMC1786	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 4000 (nM), Ref: 21561086 Ki: 3560 (nM), Ref: 21561086 Ki: 660 (nM), Ref: 21561086 Ki: 940 (nM), Ref: 21561086 Ki: 160 (nM), Ref: 21561086 Ki: 72 (nM), Ref: 21561086 IC50: 90 (nM), Ref: 21561086
TCMC1786	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 4230 (nM), Ref: 24684845 IC50: 4440 (nM), Ref: 25497963 IC50: 5460 (nM), Ref: 26100442 IC50: 5460 (nM), Ref: 26481657 IC50: 5460 (nM), Ref: 27123900
TCMC1786	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 980 (nM), Ref: 25497963
TCMC1506	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 101.2 (nM), Ref: 26498393
TCMC1506	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 268.3 (nM), Ref: 26498393
TCMC1506	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4.8 (nM), Ref: 26498393
TCMC837	TCMT690	Histone deacetylase 3	Homo sapiens	IC50: 9000 (nM), Ref: 21874153
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC1886	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 810 (nM), Ref: 26498394
TCMC1886	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 670 (nM), Ref: 26498394
TCMC1886	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 770 (nM), Ref: 26498394
TCMC1886	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 620 (nM), Ref: 26498394
TCMC1886	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 810 (nM), Ref: 26498394
TCMC1886	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8470 (nM), Ref: 26498394
TCMC1886	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 720 (nM), Ref: 26498394
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC2204	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 482 (nM), Ref: 21067924 Ki: 478 (nM), Ref: 22077347 Ki: 480 (nM), Ref: 26688270
TCMC2204	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 754 (nM), Ref: 22077347 Ki: 750 (nM), Ref: 26688270
TCMC1168	TCMT117	Kappa opioid receptor	Homo sapiens	Ki: 2515 (nM), Ref: 18166466
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC392	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 2400 (nM), Ref: 15658857 IC50: 2398.83 (nM), Ref: 19110342
TCMC192	TCMT176	Acyl coenzyme A:cholesterol acyltransferase 1	Homo sapiens	IC50: 600 (nM), Ref: 17157006
TCMC192	TCMT263	Acyl coenzyme A:cholesterol acyltransferase 2	Homo sapiens	IC50: 800 (nM), Ref: 17157006
TCMC1551	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1900 (nM), Ref: 16248836 Ki: 1900 (nM), Ref: 16248836 Ki: 800 (nM), Ref: 16248836 Ki: 250 (nM), Ref: 22696418
TCMC1551	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 760 (nM), Ref: 23746477
TCMC1551	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 40 (nM), Ref: 22696418
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477
TCMC2216	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3600 (nM), Ref: 17489632 IC50: 3100 (nM), Ref: 18798681 IC50: 3600 (nM), Ref: 19008110 IC50: 3600 (nM), Ref: 17125223 IC50: 3800 (nM), Ref: 19846295 IC50: 3900 (nM), Ref: 19632832 IC50: 3600 (nM), Ref: 19836230 IC50: 3100 (nM), Ref: 21555221 IC50: 3600 (nM), Ref: 21571537 IC50: 3100 (nM), Ref: 22940448 IC50: 2300 (nM), Ref: 21453996 Ki: 3400 (nM), Ref: 21453996 IC50: 3600 (nM), Ref: 23022281 IC50: 3080 (nM), Ref: 23141910 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2750 (nM), Ref: 23387824 IC50: 4120 (nM), Ref: 24224843 IC50: 4000 (nM), Ref: 24953600 IC50: 3500 (nM), Ref: 25559759 IC50: 3400 (nM), Ref: 25907369 Ki: 6400 (nM), Ref: 25907369 IC50: 5200 (nM), Ref: 26841168
TCMC2216	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 1900 (nM), Ref: 20100662
TCMC2216	TCMT102	Low molecular weight phosphotyrosine protein phosphatase	Homo sapiens	IC50: 7200 (nM), Ref: 21453996
TCMC2216	TCMT103	Receptor-type tyrosine-protein phosphatase F (LAR)	Homo sapiens	IC50: 3800 (nM), Ref: 21453996
TCMC2216	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 21561086 Ki: 3700 (nM), Ref: 21561086 Ki: 2100 (nM), Ref: 21561086 Ki: 2800 (nM), Ref: 21561086 Ki: 2000 (nM), Ref: 21561086 IC50: 4000 (nM), Ref: 21561086
TCMC2216	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 2400 (nM), Ref: 23387824
TCMC2216	TCMT150	Nuclear receptor ROR-gamma	Homo sapiens	IC50: 680 (nM), Ref: 10.1039/C3MD00005B IC50: 130 (nM), Ref: 24704616 IC50: 1060 (nM), Ref: 24704616 IC50: 9410 (nM), Ref: 24704616
TCMC1834	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9060 (nM), Ref: 21402476
TCMC1834	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 8030 (nM), Ref: 21402476

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2177	TCMT1120	Cell division protein ftsZ	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 25791674
TCMC1786	TCMT1107	Protease	Human immunodeficiency virus 1	IC50: 10 (ug/ml), Ref: 10691716
TCMC1858	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC2313	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC1793	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC1793	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC1793	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC1793	TCMT1251	Candida albicans	Candida albicans	MIC: 12.5 (ug/ml), Ref: 9392889
TCMC1793	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 61.5 (ug/ml), Ref: 20218656
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC855	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 19299148
TCMC1395	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 64 (ug/ml), Ref: 23369537
TCMC2351	TCMT1190	Plasmodium falciparum (isolate FcB1 / Columbia)	Plasmodium falciparum FcB1/Columbia	IC50: 16.7 (ug/ml), Ref: 21985060
TCMC2354	TCMT1251	Candida albicans	Candida albicans	IC50: 81.47 (ug/ml), Ref: 25686593
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC2385	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 12502328 MIC: 50 (ug/ml), Ref: 12502328
TCMC2385	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 50 (ug/ml), Ref: 12502328
TCMC2385	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 12502328
TCMC2388	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2388	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2388	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 12502328
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC2404	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 18710283 MIC: 28 (ug/ml), Ref: 22280816
TCMC2404	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 100 (ug/ml), Ref: 18710283 MIC: 28 (ug/ml), Ref: 22280816
TCMC2177	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 1.56 (ug/ml), Ref: 1453180 MIC: 0.6 (ug/ml), Ref: 25791674
TCMC2177	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 1453180 MIC: 0.78 (ug/ml), Ref: 1453180 MIC: 2.5 (ug/ml), Ref: 17664318 MIC: 1.25 (ug/ml), Ref: 17664318 MIC: 16 (ug/ml), Ref: 17664318 MIC: 2 (ug/ml), Ref: 17664318 MIC: 1.5 (ug/ml), Ref: 25791674
TCMC2177	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 0.78 (ug/ml), Ref: 1453180
TCMC2177	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 16 (ug/ml), Ref: 25791674
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC1786	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 21.8 (ug/ml), Ref: 9748372
TCMC1786	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC2482	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2482	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2482	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.1 (ug/ml), Ref: 9392889
TCMC2482	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 3.1 (ug/ml), Ref: 9392889
TCMC2482	TCMT1251	Candida albicans	Candida albicans	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC887	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 62.5 (ug/ml), Ref: 10395496
TCMC1767	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 60 (ug/ml), Ref: 20384293
TCMC1767	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC60	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2547	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 6.25 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2547	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 6.25 (ug/ml), Ref: 12502328
TCMC2547	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 12502328
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC924	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC2578	TCMT1251	Candida albicans	Candida albicans	IC50: 82.98 (ug/ml), Ref: 25686593
TCMC915	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 25791674
TCMC915	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2581	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC2069	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 12502328 MIC: 50 (ug/ml), Ref: 12502328
TCMC2069	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 50 (ug/ml), Ref: 12502328
TCMC2069	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 12502328
TCMC1168	TCMT1246	Escherichia coli	Escherichia coli	MIC: 25 (ug/ml), Ref: 9392889 MIC: 2.5 (ug/ml), Ref: 10217726
TCMC1168	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 50 (ug/ml), Ref: 9392889
TCMC1168	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 9392889 MIC: 12.5 (ug/ml), Ref: 10217726 MIC: 25 (ug/ml), Ref: 10217726
TCMC1168	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 6.25 (ug/ml), Ref: 9392889 MIC: 12.5 (ug/ml), Ref: 10217726
TCMC1168	TCMT1251	Candida albicans	Candida albicans	MIC: 25 (ug/ml), Ref: 9392889
TCMC1168	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.2 (ug/ml), Ref: 20218656
TCMC2613	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 15 (ug/ml), Ref: 9748372
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC2035	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1033	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 100 (ug/ml), Ref: 10924184
TCMC1033	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10924184
TCMC1033	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 30 (ug/ml), Ref: 18564877
TCMC1551	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 20832915
TCMC395	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC2671	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC2671	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC1578	TCMT1408	Colletotrichum gloeosporioides	Colletotrichum gloeosporioides	IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578	TCMT1245	Phytophthora cactorum	Phytophthora cactorum	IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC624	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MBC: 6.25 (ug/ml), Ref: 12502328 MIC: 6.25 (ug/ml), Ref: 12502328 MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC624	TCMT1214	Enterococcus faecium	Enterococcus faecium	MBC: 6.25 (ug/ml), Ref: 12502328 MIC: 6.25 (ug/ml), Ref: 12502328
TCMC624	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 1.56 (ug/ml), Ref: 12502328 MIC: 1.56 (ug/ml), Ref: 12502328
TCMC1776	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC2706	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MBC: 6.25 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328 MBC: 3.13 (ug/ml), Ref: 12502328
TCMC2706	TCMT1214	Enterococcus faecium	Enterococcus faecium	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2706	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 1.56 (ug/ml), Ref: 12502328 MBC: 1.56 (ug/ml), Ref: 12502328
TCMC2714	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 1.4 (ug/ml), Ref: 22280816
TCMC2714	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 25.3 (ug/ml), Ref: 22280816
TCMC2718	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2718	TCMT1214	Enterococcus faecium	Enterococcus faecium	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2718	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328 MBC: 1.56 (ug/ml), Ref: 12502328 MIC: 1.56 (ug/ml), Ref: 12502328
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915
TCMC2216	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 6.5 (ug/ml), Ref: 9748372
TCMC2216	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 100 (ug/ml), Ref: 20542692
TCMC2216	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041