Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC879	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 230 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC417	TCMT127	Poly [ADP-ribose] polymerase-1	Homo sapiens	IC50: 7585.78 (nM), Ref: 23574272 IC50: 7500 (nM), Ref: 23574272
TCMC417	TCMT128	Tankyrase-2	Homo sapiens	IC50: 870.96 (nM), Ref: 23574272 IC50: 870 (nM), Ref: 23574272
TCMC417	TCMT129	Tankyrase-1	Homo sapiens	IC50: 645.65 (nM), Ref: 23574272 IC50: 630 (nM), Ref: 23574272
TCMC417	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 2000 (nM), Ref: 24368208
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC908	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 6000 (nM), Ref: 15689157 IC50: 6000 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC908	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 2600 (nM), Ref: 15267241 IC50: 1 (nM), Ref: 20413308 IC50: 800 (nM), Ref: 10.1039/C3MD00166K IC50: 500 (nM), Ref: 26301554
TCMC908	TCMT223	Aldose reductase	Homo sapiens	IC50: 8500 (nM), Ref: 18165015
TCMC908	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	IC50: 670 (nM), Ref: 19097799 Ki: 110 (nM), Ref: 19097799
TCMC908	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 153 (nM), Ref: 20696580 IC50: 1290 (nM), Ref: 23600958
TCMC908	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 84 (nM), Ref: 20696580 IC50: 54 (nM), Ref: 20832301 IC50: 570 (nM), Ref: 23600958
TCMC908	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 24 (nM), Ref: 20696580
TCMC908	TCMT87	Cytochrome P450 2C9	Homo sapiens	IC50: 5225 (nM), Ref: 20832301
TCMC908	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5490 (nM), Ref: 22487176 Ki: 5420 (nM), Ref: 22487176
TCMC908	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4380 (nM), Ref: 22487176 Ki: 4310 (nM), Ref: 22487176
TCMC908	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 2650 (nM), Ref: 22487176 Ki: 2710 (nM), Ref: 22487176
TCMC908	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8960 (nM), Ref: 22487176 Ki: 9070 (nM), Ref: 22487176 Ki: 34.7 (nM), Ref: 26498393
TCMC908	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 537.75 (nM), Ref: 26498393
TCMC908	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 171.41 (nM), Ref: 26498393
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC704	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 4000 (nM), Ref: 21030469 IC50: 3600 (nM), Ref: 21030469
TCMC2061	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 9550 (nM), Ref:
TCMC795	TCMT223	Aldose reductase	Homo sapiens	IC50: 8000 (nM), Ref: 24341381
TCMC416	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 4500 (nM), Ref: 14592472
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1965	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 452.6 (nM), Ref: 26498393
TCMC1965	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 515 (nM), Ref: 26498393
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC2054	TCMT240	Salivary alpha-amylase	Homo sapiens	IC50: 9640 (nM), Ref: 18507367
TCMC2054	TCMT384	G protein-coupled receptor kinase 6	Homo sapiens	IC50: 6610 (nM), Ref:
TCMC2054	TCMT283	Receptor-type tyrosine-protein phosphatase S	Homo sapiens	IC50: 600 (nM), Ref: 26602279
TCMC1735	TCMT599	Ubiquitin-conjugating enzyme E2 N	Homo sapiens	IC50: 8695 (nM), Ref: IC50: 5771 (nM), Ref: IC50: 6662 (nM), Ref:
TCMC1113	TCMT47	Apoptosis regulator Bcl-2	Homo sapiens	Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC2003	TCMT82	Estrogen receptor alpha	Homo sapiens	Ki: 785 (nM), Ref: 15634023
TCMC2003	TCMT164	Cyclooxygenase-1	Homo sapiens	IC50: 2840 (nM), Ref: 16814546 IC50: 4120 (nM), Ref: 18063374 IC50: 625 (nM), Ref:
TCMC2003	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 996 (nM), Ref: 17604631 IC50: 750 (nM), Ref: 20527891 IC50: 996 (nM), Ref: 26850006
TCMC2003	TCMT329	Quinone reductase 2	Homo sapiens	IC50: 960 (nM), Ref: 19265439 IC50: 450 (nM), Ref: 20036559 IC50: 450 (nM), Ref: 20356739 IC50: 960 (nM), Ref: 21261296 IC50: 6900 (nM), Ref: 23953689 Ki: 88 (nM), Ref: 23953689 IC50: 1400 (nM), Ref: 26854376 IC50: 913 (nM), Ref: 26854376
TCMC2003	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2210 (nM), Ref: 20674354
TCMC2003	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2770 (nM), Ref: 20674354
TCMC2003	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 9090 (nM), Ref: 20674354
TCMC2003	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4470 (nM), Ref: 20674354
TCMC2003	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4750 (nM), Ref: 20674354
TCMC2003	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4640 (nM), Ref: 20674354
TCMC2003	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8070 (nM), Ref: 20674354
TCMC2003	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4350 (nM), Ref: 20674354
TCMC2003	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 810 (nM), Ref: 20674354
TCMC2003	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 950 (nM), Ref: 20674354
TCMC2003	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4090 (nM), Ref: 20674354
TCMC2003	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 830 (nM), Ref: 20674354
TCMC2003	TCMT729	PI3-kinase p110-alpha subunit	Homo sapiens	IC50: 250 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT730	PI3-kinase p110-beta subunit	Homo sapiens	IC50: 500 (nM), Ref: 10.1039/C2MD20044A
TCMC2003	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4100 (nM), Ref: 27190601 IC50: 2600 (nM), Ref: 27190601
TCMC1334	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 4200 (nM), Ref: 19481465
TCMC1334	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 5610 (nM), Ref: 24900561 Ki: 5.61 (nM), Ref: 27078864
TCMC1334	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 6460 (nM), Ref: 24900561 Ki: 6.46 (nM), Ref: 27078864
TCMC143	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 1610 (nM), Ref:
TCMC706	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 9510 (nM), Ref: 19028102
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC614	TCMT151	Protein kinase C alpha	Homo sapiens	IC50: 9300 (nM), Ref: 9834166
TCMC1281	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 10 (nM), Ref: 19564108 IC50: 18.6 (nM), Ref: 22148241 IC50: 6 (nM), Ref: 22360639
TCMC1281	TCMT209	11-beta-hydroxysteroid dehydrogenase 2	Homo sapiens	IC50: 1 (nM), Ref: 19564108 IC50: 0.7 (nM), Ref: 22148241 IC50: 0.4 (nM), Ref: 22360639
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC22	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 1000 (nM), Ref: 15679319 Ki: 177 (nM), Ref: 16248836
TCMC2063	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 126 (nM), Ref: 12825922 IC50: 180 (nM), Ref: 18983139 Ki: 110 (nM), Ref: 18983139 IC50: 184 (nM), Ref: 18588282 Ki: 170 (nM), Ref: 21726069 IC50: 280 (nM), Ref: 23582449 Ki: 82 (nM), Ref: 23466604 IC50: 160 (nM), Ref: 23466604 IC50: 180 (nM), Ref: 26988801
TCMC2063	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 65 (nM), Ref: 12825922 Ki: 100 (nM), Ref: 15357994 IC50: 200 (nM), Ref: 18983139 Ki: 93 (nM), Ref: 18983139 IC50: 262 (nM), Ref: 18588282 IC50: 27.5 (nM), Ref: 20170099 Ki: 84 (nM), Ref: 21726069 Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8 IC50: 180 (nM), Ref: 23582449 Ki: 50 (nM), Ref: 23466604 IC50: 100 (nM), Ref: 23466604 Ki: 33 (nM), Ref: 24805037 Ki: 33 (nM), Ref: 25557493 IC50: 120 (nM), Ref: 26988801 Ki: 100 (nM), Ref: 26996373
TCMC2063	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 8.1 (nM), Ref: 12825922 IC50: 0.61 (nM), Ref: 18983139 Ki: 0.22 (nM), Ref: 18983139 IC50: 2.55 (nM), Ref: 12713409 IC50: 1.5 (nM), Ref: 18588282 Ki: 0.13 (nM), Ref: 21726069 IC50: 0.49 (nM), Ref: 23582449 Ki: 0.11 (nM), Ref: 23466604 IC50: 0.29 (nM), Ref: 23466604 Ki: 1.4 (nM), Ref: 24763360 Ki: 0.8 (nM), Ref: 24805037 Ki: 0.8 (nM), Ref: 25557493 IC50: 0.25 (nM), Ref: 26988801
TCMC2063	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 14 (nM), Ref: 15081042 Ki: 8.2 (nM), Ref: 16392816 Ki: 14 (nM), Ref: 16257207 Ki: 120 (nM), Ref: 18468904 Ki: 160 (nM), Ref: 18468904 Ki: 130 (nM), Ref: 18468904 Ki: 150 (nM), Ref: 18468904 Ki: 320 (nM), Ref: 11975483 Ki: 690 (nM), Ref: 17067154 Ki: 323.59 (nM), Ref: 23301527 Ki: 320 (nM), Ref: 23301527
TCMC2063	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 12 (nM), Ref: 15081042 Ki: 13 (nM), Ref: 12954071 Ki: 13 (nM), Ref: 16392816 Ki: 12 (nM), Ref: 16257207 Ki: 13.49 (nM), Ref: 24582985
TCMC2063	TCMT314	Serotonin 2c (5-HT2c) receptor	Homo sapiens	Ki: 6.9 (nM), Ref: 15081042 Ki: 8.3 (nM), Ref: 12954071 Ki: 8.3 (nM), Ref: 16392816 Ki: 6.9 (nM), Ref: 16257207 Ki: 130 (nM), Ref: 11975483 Ki: 20 (nM), Ref: 17067154 Ki: 79.43 (nM), Ref: 23301527 Ki: 79 (nM), Ref: 23301527
TCMC2063	TCMT815	Serotonin 1d (5-HT1d) receptor	Homo sapiens	Ki: 5.5 (nM), Ref: 8071931 Ki: 0.5 (nM), Ref: 18507369
TCMC2063	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 2.5 (nM), Ref: 7658447 IC50: 1.2 (nM), Ref: 12954071 Ki: 1.259 (nM), Ref: 18433113 Ki: 10000 (nM), Ref: 18433113 Ki: 0.62 (nM), Ref: 22748706 Ki: 0.9 (nM), Ref: 23332346 Ki: 9.5 (nM), Ref: 24161678 Ki: 2.08 (nM), Ref: 25128671
TCMC2063	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 79 (nM), Ref: 16250647
TCMC2063	TCMT816	Serotonin 1b (5-HT1b) receptor	Homo sapiens	Ki: 1.1 (nM), Ref: 18507369 IC50: 29 (nM), Ref: 18983139 Ki: 18 (nM), Ref: 18983139 Ki: 14 (nM), Ref: 21726069 IC50: 12 (nM), Ref: 23582449 Ki: 4 (nM), Ref: 23466604 IC50: 6.5 (nM), Ref: 23466604
TCMC2063	TCMT817	Serotonin 4 (5-HT4) receptor	Homo sapiens	Ki: 1049 (nM), Ref: 19334715 Ki: 500 (nM), Ref: 17067154 Ki: 29.51 (nM), Ref: 19223092 Ki: 109.65 (nM), Ref: 19223092
TCMC2063	TCMT645	Serotonin 1e (5-HT1e) receptor	Homo sapiens	Ki: 10.72 (nM), Ref: 24365159 Ki: 11 (nM), Ref: 24365159
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC606	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 251 (nM), Ref: 20696580
TCMC606	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 86 (nM), Ref: 20696580
TCMC606	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 12 (nM), Ref: 20696580
TCMC755	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	Ki: 600 (nM), Ref: 21739938
TCMC755	TCMT81	Arachidonate 12-lipoxygenase	Homo sapiens	Ki: 1600 (nM), Ref: 21739938
TCMC755	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC755	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 4400 (nM), Ref: 21030469 IC50: 7000 (nM), Ref: 21030469
TCMC755	TCMT384	G protein-coupled receptor kinase 6	Homo sapiens	IC50: 8700 (nM), Ref:
TCMC1105	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 2000 (nM), Ref: 19414254
TCMC1105	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2500 (nM), Ref: 27173800
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC937	TCMT232	P-glycoprotein 1	Homo sapiens	IC50: 11.5 (nM), Ref: 23332369 IC50: 6.6 (nM), Ref: 23895532
TCMC937	TCMT801	Tubulin beta-3 chain	Homo sapiens	IC50: 5.2 (nM), Ref: 23332369 IC50: 5.7 (nM), Ref: 23895532
TCMC1203	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 8000 (nM), Ref: 10.1039/C4MD00086B
TCMC1523	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 1440 (nM), Ref: 24900561
TCMC1523	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 3150 (nM), Ref: 24900561
TCMC4	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 6000 (nM), Ref: 14592472
TCMC1798	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1480 (nM), Ref: 23411073
TCMC1123	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 1284 (nM), Ref: 20696580
TCMC1123	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 72.8 (nM), Ref: 26498393
TCMC1123	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.3 (nM), Ref: 26498393
TCMC1123	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 31.1 (nM), Ref: 26498393
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC2004	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 800 (nM), Ref: 10.1039/C3MD00317E Ki: 2100 (nM), Ref: 10.1039/C0MD00242A
TCMC2004	TCMT215	Cytochrome P450 1A1	Homo sapiens	Ki: 160 (nM), Ref: 10.1039/C0MD00242A
TCMC1892	TCMT508	Tyrosine-protein kinase SYK	Homo sapiens	IC50: 10000 (nM), Ref: 23917087
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC2055	TCMT747	ATP-binding cassette sub-family G member 2	Homo sapiens	IC50: 10000 (nM), Ref: 22822035
TCMC710	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554
TCMC710	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 710 (nM), Ref: 18533708
TCMC710	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 800 (nM), Ref: 19414254
TCMC710	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5200 (nM), Ref: 19592245
TCMC710	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 795 (nM), Ref: 20696580
TCMC710	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 427 (nM), Ref: 20696580
TCMC710	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC710	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1450 (nM), Ref: 23411073
TCMC710	TCMT128	Tankyrase-2	Homo sapiens	IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272
TCMC710	TCMT129	Tankyrase-1	Homo sapiens	IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272
TCMC710	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844
TCMC710	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC908	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 11.62 (ug/ml), Ref: 20116898
TCMC2054	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 14.48 (ug/ml), Ref: 20116898
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC2063	TCMT1086	Isocitrate lyase	Candida albicans	IC50: 53 (ug/ml), Ref: 21035332
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1203	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28.5 (ug/ml), Ref: 9461665
TCMC2292	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 13.15 (ug/ml), Ref: 20116898
TCMC2304	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28.3 (ug/ml), Ref: 9461665
TCMC710	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 8.54 (ug/ml), Ref: 20116898
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC908	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 11170636 MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1901	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1236	Mycobacterium bovis	Mycobacterium bovis BCG	MIC: 26 (ug/ml), Ref: 18849164
TCMC1901	TCMT1217	Bacillus anthracis	Bacillus anthracis	MIC: 8 (ug/ml), Ref: 18849164
TCMC1901	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1191	Bacillus megaterium	Bacillus megaterium	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 8 (ug/ml), Ref: 18849164
TCMC1901	TCMT1260	Streptococcus agalactiae	Streptococcus agalactiae	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1322	Streptococcus mitis	Streptococcus mitis	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1410	Listeria monocytogenes	Listeria monocytogenes	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1323	Corynebacterium pseudodiphtheriticum	Corynebacterium pseudodiphtheriticum	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1324	Corynebacterium diphtheriae	Corynebacterium diphtheriae	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1319	Corynebacterium xerosis	Corynebacterium xerosis	MIC: 16 (ug/ml), Ref: 18849164
TCMC795	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.6 (ug/ml), Ref: 15844943
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC1113	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 15863332
TCMC2003	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1251	Candida albicans	Candida albicans	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1246	Escherichia coli	Escherichia coli	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 0 (ug/ml), Ref: 12036362
TCMC2003	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12036362
TCMC2003	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753
TCMC2003	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 25 (ug/ml), Ref: 20022753
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC614	TCMT1454	Bacillus subtilis	Bacillus subtilis	IC50: 98.5 (ug/ml), Ref: 25981688
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC606	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 5.5 (ug/ml), Ref: 19299148
TCMC755	TCMT1251	Candida albicans	Candida albicans	IC50: 6 (ug/ml), Ref: 12502337
TCMC755	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC755	TCMT1249	Dengue virus 2	Dengue virus 2	IC50: 6.46 (ug/ml), Ref: 25564380
TCMC1105	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 23534483
TCMC1105	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1 (ug/ml), Ref: 23534483
TCMC1105	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 23534483 MIC: 4 (ug/ml), Ref: 23534483
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1203	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 22.6 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2642	TCMT1251	Candida albicans	Candida albicans	IC50: 3.5 (ug/ml), Ref: 12088427 MIC: 6.25 (ug/ml), Ref: 12088427
TCMC2642	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 12088427 IC50: 2 (ug/ml), Ref: 12088427
TCMC2642	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	IC50: 2 (ug/ml), Ref: 12088427 MIC: 3.13 (ug/ml), Ref: 12088427
TCMC2642	TCMT1355	Rhodococcus equi	Rhodococcus equi	MIC: 10 (ug/ml), Ref: 19639965
TCMC2642	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 12 (ug/ml), Ref: 19874044
TCMC2642	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC2642	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2014	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 10 (ug/ml), Ref: 17220400
TCMC1523	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 12.5 (ug/ml), Ref: 18611050 MIC: 25 (ug/ml), Ref: 21131198 MIC: 25 (ug/ml), Ref: 21401117 MIC: 16 (ug/ml), Ref: 22424614 MIC: 32 (ug/ml), Ref: 22424614 MBC: 32 (ug/ml), Ref: 22424614
TCMC1523	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 6.25 (ug/ml), Ref: 18611050 MIC: 12.5 (ug/ml), Ref: 21131198
TCMC1523	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 12.5 (ug/ml), Ref: 18611050 MIC: 12.5 (ug/ml), Ref: 21131198 MIC: 12.5 (ug/ml), Ref: 21401117
TCMC1523	TCMT1201	Staphylococcus epidermidis ATCC 12228	Staphylococcus epidermidis ATCC 12228	MIC: 12.5 (ug/ml), Ref: 21401117
TCMC1523	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 12.5 (ug/ml), Ref: 21401117
TCMC1523	TCMT1219	Enterococcus	Enterococcus	MIC: 32 (ug/ml), Ref: 22424614 MBC: 32 (ug/ml), Ref: 22424614
TCMC1123	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812
TCMC1123	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 25 (ug/ml), Ref: 15679330
TCMC1892	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 20022753 MBC: 100 (ug/ml), Ref: 20022753
TCMC1892	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 50 (ug/ml), Ref: 20022753 MBC: 100 (ug/ml), Ref: 20022753
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC2699	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 6.3 (ug/ml), Ref: 14995101
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1246	Escherichia coli	Escherichia coli	MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC710	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC710	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2806	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.5 (ug/ml), Ref: 18524594
TCMC1113	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 16 (nM), Ref: 17263522
TCMC4	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 40 (nM), Ref: 16722653