Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC619	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 158.49 (nM), Ref: 18077164
TCMC619	TCMT291	Muscarinic acetylcholine receptor M3	Homo sapiens	Ki: 7079.46 (nM), Ref: 18077164
TCMC619	TCMT551	Muscarinic acetylcholine receptor M4	Homo sapiens	Ki: 8511.38 (nM), Ref: 18077164
TCMC619	TCMT290	Muscarinic acetylcholine receptor M5	Homo sapiens	Ki: 9772.37 (nM), Ref: 18077164
TCMC619	TCMT241	Neuronal acetylcholine receptor protein alpha-7 subunit	Homo sapiens	Ki: 7943.28 (nM), Ref: 21920761
TCMC415	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 1800 (nM), Ref: 14592472
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC1330	TCMT246	Histamine H4 receptor	Homo sapiens	Ki: 14.45 (nM), Ref: 14640553 Ki: 7.943 (nM), Ref: 15454206 Ki: 12.02 (nM), Ref: 18357976 Ki: 13.4 (nM), Ref: 18459760 Ki: 12.02 (nM), Ref: 20192225 Ki: 60 (nM), Ref: 20452213 Ki: 7.943 (nM), Ref: 21044842 Ki: 12.59 (nM), Ref: 21044842 Ki: 12.02 (nM), Ref: 21348462 Ki: 15.85 (nM), Ref: 22003888 Ki: 9 (nM), Ref: 22153663 Ki: 19.95 (nM), Ref: 10.1039/C2MD20212C Ki: 4.8 (nM), Ref: 25993395 Ki: 8 (nM), Ref: 25993395 Ki: 15.85 (nM), Ref: 10.1039/C5MD00022J
TCMC1330	TCMT242	Histamine H3 receptor	Homo sapiens	Ki: 5.2 (nM), Ref: 20384344 Ki: 10 (nM), Ref: 21044842 Ki: 11.75 (nM), Ref: 21348462 Ki: 6.31 (nM), Ref: 22003888 Ki: 16 (nM), Ref: 25993395
TCMC1330	TCMT245	Histamine H2 receptor	Homo sapiens	Ki: 5000 (nM), Ref: 25993395
TCMC1330	TCMT244	Histamine H1 receptor	Homo sapiens	Ki: 6000 (nM), Ref: 25993395
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC719	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 14 (nM), Ref: 10891110 IC50: 115 (nM), Ref: 11597415
TCMC719	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 40 (nM), Ref: 10891110 Ki: 40 (nM), Ref: 9622546 Ki: 2454.71 (nM), Ref: 18182302
TCMC719	TCMT551	Muscarinic acetylcholine receptor M4	Homo sapiens	Ki: 2400 (nM), Ref: 10891110 Ki: 26 (nM), Ref: 10891110 Ki: 2400 (nM), Ref: 9622546
TCMC1104	TCMT678	Inhibitor of apoptosis protein 3	Homo sapiens	IC50: 4100 (nM), Ref: 15115387
TCMC1104	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1700 (nM), Ref: 25765759 IC50: 60 (nM), Ref: 25765759 IC50: 800 (nM), Ref: 25765759 IC50: 60 (nM), Ref: 25765759 IC50: 3500 (nM), Ref: 25765759
TCMC1104	TCMT679	Macrophage-expressed gene 1 protein	Homo sapiens	IC50: 210 (nM), Ref: 25765759 IC50: 210 (nM), Ref: 25765759
TCMC1104	TCMT680	Histone acetyltransferase PCAF	Homo sapiens	IC50: 7200 (nM), Ref: 26701186
TCMC2124	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 4703 (nM), Ref:
TCMC2124	TCMT289	Thromboxane-A synthase	Homo sapiens	IC50: 325 (nM), Ref:
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC1204	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2500 (nM), Ref: 14592472
TCMC878	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2420 (nM), Ref: 20674354
TCMC878	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1840 (nM), Ref: 20674354
TCMC878	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 3580 (nM), Ref: 20674354
TCMC878	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4900 (nM), Ref: 20674354
TCMC878	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4210 (nM), Ref: 20674354
TCMC878	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4020 (nM), Ref: 20674354
TCMC878	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4910 (nM), Ref: 20674354
TCMC878	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 450 (nM), Ref: 20674354
TCMC878	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5030 (nM), Ref: 20674354
TCMC878	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4720 (nM), Ref: 20674354

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2124	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 50 (ug/ml), Ref: 1710653
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1104	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1104	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 35.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 49 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 14.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC2528	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 50 (ug/ml), Ref: 20476748
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1733	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 17.2 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2808	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 27 (ug/ml), Ref: 10425115