Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC172	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 310 (nM), Ref: 23332346
TCMC658	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 122 (nM), Ref: 26125082
TCMC1957	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 78 (nM), Ref: 26125082
TCMC1258	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 966 (nM), Ref: 25695425
TCMC1258	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 43 (nM), Ref: 25695425
TCMC1258	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 171 (nM), Ref: 25695425
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC1748	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 85 (nM), Ref: 16562853 Ki: 314 (nM), Ref: 25695425
TCMC1748	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 373 (nM), Ref: 25695425
TCMC1748	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 20 (nM), Ref: 25695425
TCMC1748	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 306 (nM), Ref: 25695425
TCMC1748	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 566 (nM), Ref: 25695425
TCMC1748	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 323 (nM), Ref: 25695425
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC6	TCMT46	Coagulation factor III	Homo sapiens	IC50: 152.43 (nM), Ref: 23199480
TCMC6	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 50 (nM), Ref: 23332346
TCMC6	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 305 (nM), Ref: 23332346
TCMC6	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 149 (nM), Ref: 23332346
TCMC2053	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 22 (nM), Ref: 23332346
TCMC2053	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 214 (nM), Ref: 23332346
TCMC162	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 1189 (nM), Ref: 23332346
TCMC264	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 105 (nM), Ref: 23332346
TCMC264	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 6.6 (nM), Ref: 23332346
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC858	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 66 (nM), Ref: 23332346
TCMC858	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 119 (nM), Ref: 23332346
TCMC38	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 529 (nM), Ref: 23332346
TCMC429	TCMT853	Sigma opioid receptor	Homo sapiens	Ki: 106 (nM), Ref: 27032890
TCMC429	TCMT651	Dopamine D3 receptor	Homo sapiens	Ki: 37 (nM), Ref: 27032890
TCMC429	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 102 (nM), Ref: 27032890
TCMC429	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 15 (nM), Ref: 27032890
TCMC1655	TCMT643	Alpha-1a adrenergic receptor	Homo sapiens	Ki: 430 (nM), Ref: 15664832
TCMC234	TCMT615	Sentrin-specific protease 8	Homo sapiens	IC50: 5470 (nM), Ref:
TCMC234	TCMT616	Sentrin-specific protease 7	Homo sapiens	IC50: 4630 (nM), Ref:
TCMC234	TCMT617	Sentrin-specific protease 6	Homo sapiens	IC50: 1860 (nM), Ref:
TCMC2146	TCMT46	Coagulation factor III	Homo sapiens	IC50: 8.35 (nM), Ref: 23199480
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344
TCMC265	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 91 (nM), Ref: 23332346
TCMC265	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 4.5 (nM), Ref: 23332346

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC658	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 49.81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1957	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC858	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.555 (ug/ml), Ref: 3286870 IC50: 1.739 (ug/ml), Ref: 3286870
TCMC858	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 42.71 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1