TCM Putative Target References: TCMFx1600


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2037
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 9920 (nM), Ref: 18501600
Ki: 9900 (nM), Ref: 18579385
Ki: 9900 (nM), Ref: 26520662
TCMC2037
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 7120 (nM), Ref: 18501600
Ki: 7100 (nM), Ref: 18579385
Ki: 7100 (nM), Ref: 26520662
TCMC2037
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 8800 (nM), Ref: 18579385
TCMC1956
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 1080 (nM), Ref: 21282059
TCMC1956
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 470 (nM), Ref: 21282059
TCMC1956
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 4450 (nM), Ref: 21282059
TCMC1956
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4090 (nM), Ref: 21282059
TCMC1956
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 4720 (nM), Ref: 21669522
Ki: 4720 (nM), Ref: 22687439
TCMC1956
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 2450 (nM), Ref: 22687439
TCMC1956
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 690 (nM), Ref: 22668600
TCMC1956
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7870 (nM), Ref: 22668600
TCMC916
TCMT161 Hydroxycarboxylic acid receptor 2 Homo sapiens Ki: 4900 (nM), Ref: 21167710
TCMC1839
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 9800 (nM), Ref: 18501600
Ki: 9800 (nM), Ref: 18579385
Ki: 920 (nM), Ref: 20185318
TCMC1839
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4800 (nM), Ref: 18579385
Ki: 6270 (nM), Ref: 20185318
TCMC1839
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 9200 (nM), Ref: 18579385
Ki: 3670 (nM), Ref: 20185318
TCMC1839
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 6160 (nM), Ref: 20185318
TCMC1839
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 3730 (nM), Ref: 20185318
TCMC1839
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 4080 (nM), Ref: 20185318
TCMC1839
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 5700 (nM), Ref: 20185318
TCMC1839
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 7130 (nM), Ref: 20185318
TCMC1839
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 7780 (nM), Ref: 20185318
TCMC1839
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 6610 (nM), Ref: 20185318
TCMC1839
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 870 (nM), Ref: 20185318
TCMC2018
TCMT907 Farnesyl diphosphate synthase Homo sapiens IC50: 452.9 (nM), Ref: 18327899
Ki: 82.2 (nM), Ref: 18327899
IC50: 5.7 (nM), Ref: 18327899
Ki: 0.36 (nM), Ref: 18327899
IC50: 5.7 (nM), Ref: 18434151
IC50: 300 (nM), Ref: 20801032
IC50: 11 (nM), Ref: 22390415
IC50: 860 (nM), Ref: 22390415
IC50: 11 (nM), Ref: 22884353
IC50: 10 (nM), Ref: 21780776
IC50: 5.2 (nM), Ref: 23998921
IC50: 11 (nM), Ref: 23998921
IC50: 6 (nM), Ref: 24911527
IC50: 11 (nM), Ref: 25630225
IC50: 6 (nM), Ref: 25935643
IC50: 0.36 (nM), Ref: 25815158
IC50: 82 (nM), Ref: 25815158

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2417
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 16 (ug/ml), Ref: 25760525
MIC: 32 (ug/ml), Ref: 25760525
TCMC2417
TCMT1187 Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC: 16 (ug/ml), Ref: 25760525
TCMC2417
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 16 (ug/ml), Ref: 25760525
TCMC2417
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 8 (ug/ml), Ref: 25760525
TCMC495
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 7.33 (ug/ml), Ref: 8759172
IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 7.33 (ug/ml), Ref: 8759172
IC50: 5.56 (ug/ml), Ref: 8759172
TCMC2606
TCMT1248 Hepatitis C virus Hepatitis C virus IC50: 20 (ug/ml), Ref: 19904996
TCMC1889
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2733
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 4 (ug/ml), Ref: 14698179
TCMC2734
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 32 (ug/ml), Ref: 15715470
MIC: 64 (ug/ml), Ref: MIC: 32 (ug/ml), Ref: 19179074
TCMC2735
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 8 (ug/ml), Ref: 15715470
MIC: 8 (ug/ml), Ref: 22194678
MIC: 8 (ug/ml), Ref: 19179074
TCMC2733
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 4 (ug/ml), Ref: 10.6019/CHEMBL1201861
MIC: 2 (ug/ml), Ref: 19179074
MIC: 4 (ug/ml), Ref: 16643039
TCMC2735
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 8 (ug/ml), Ref: 17190457
TCMC2735
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 16 (ug/ml), Ref: 20405847
TCMC2733
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 4 (ug/ml), Ref: 12617583
TCMC2734
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 8 (ug/ml), Ref: 12617583
TCMC2734
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 8 (ug/ml), Ref: 17438047
TCMC2735
TCMT1187 Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC: 64 (ug/ml), Ref: 17438047
TCMC2733
TCMT1187 Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC: 4 (ug/ml), Ref: 17438047
TCMC2772
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 16 (ug/ml), Ref: 25856683
MIC: 8 (ug/ml), Ref: 10.6019/CHEMBL1201861
MIC: 16 (ug/ml), Ref: 15497933
TCMC2772
TCMT1187 Enterococcus faecalis ATCC 29212 Enterococcus faecalis ATCC 29212 MIC: 64 (ug/ml), Ref: 15679329
TCMC2772
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 8 (ug/ml), Ref: 18541727
TCMC2772
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 8 (ug/ml), Ref:
TCMC2018
TCMT1155 Farnesyl pyrophosphate synthase Leishmania major Ki: 17 (nM), Ref: 15828834