Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2093	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 57 (nM), Ref: 17149865
TCMC2093	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 68 (nM), Ref: 17149865
TCMC758	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	Ki: 175.5 (nM), Ref: 25978962 IC50: 488.8 (nM), Ref: 25978962
TCMC737	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 168 (nM), Ref: 26498393
TCMC737	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 5591.2 (nM), Ref: 26498393
TCMC737	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 423.7 (nM), Ref: 26498393
TCMC737	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4.9 (nM), Ref: 26498393
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC2228	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 6830 (nM), Ref: 21282059
TCMC2228	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 6180 (nM), Ref: 21282059
TCMC2228	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8250 (nM), Ref: 21282059
TCMC2228	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 6700 (nM), Ref: 21282059
TCMC2228	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 6480 (nM), Ref: 22687439
TCMC2228	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 740 (nM), Ref: 22668600
TCMC2228	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7150 (nM), Ref: 22668600
TCMC1551	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1900 (nM), Ref: 16248836 Ki: 1900 (nM), Ref: 16248836 Ki: 800 (nM), Ref: 16248836 Ki: 250 (nM), Ref: 22696418
TCMC1551	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 760 (nM), Ref: 23746477
TCMC1551	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 40 (nM), Ref: 22696418
TCMC679	TCMT624	Heat shock protein HSP 90-beta	Homo sapiens	IC50: 930 (nM), Ref: 7853008 IC50: 1410 (nM), Ref: IC50: 24 (nM), Ref: 10.1007/s00044-012-0301-x IC50: 90 (nM), Ref: 19734910
TCMC679	TCMT619	Heat shock protein HSP 90-alpha	Homo sapiens	Ki: 680 (nM), Ref:
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477
TCMC1343	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 90 (nM), Ref: 18501600 Ki: 90 (nM), Ref: 18579385
TCMC1343	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7800 (nM), Ref: 18579385
TCMC1343	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8200 (nM), Ref: 18579385

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1381	TCMT1251	Candida albicans	Candida albicans	IC50: 3 (ug/ml), Ref: 17112640 IC50: 2 (ug/ml), Ref: 12502337
TCMC1381	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 7 (ug/ml), Ref: 17112640 IC50: 45 (ug/ml), Ref: 12502337
TCMC1381	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 31.2 (ug/ml), Ref: 18951808
TCMC1381	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 31.2 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.62 (ug/ml), Ref: 22169259
TCMC1381	TCMT1246	Escherichia coli	Escherichia coli	MIC: 2 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051 MIC: 0.25 (ug/ml), Ref: 20160051 MIC: 8 (ug/ml), Ref: 20160051
TCMC1381	TCMT1179	Escherichia coli ATCC 8739	Escherichia coli ATCC 8739	MIC: 8 (ug/ml), Ref: 20160051
TCMC1381	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 16 (ug/ml), Ref: 20160051 MIC: 32 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051 MIC: 8 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051
TCMC1381	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 32 (ug/ml), Ref: 20160051 MIC: 4 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051 MIC: 0.5 (ug/ml), Ref: 20160051
TCMC1381	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 64 (ug/ml), Ref: 20160051 MIC: 16 (ug/ml), Ref: 20160051
TCMC1381	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 64 (ug/ml), Ref: 20160051 MIC: 4 (ug/ml), Ref: 20160051
TCMC1381	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 8 (ug/ml), Ref: 20160051 MIC: 64 (ug/ml), Ref: 20160051 MIC: 1 (ug/ml), Ref: 20160051
TCMC1381	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 18 (ug/ml), Ref: 22280816
TCMC2362	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 32 (ug/ml), Ref: 20427099
TCMC2362	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MIC: 1 (ug/ml), Ref: 20427099
TCMC2362	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 1 (ug/ml), Ref: 20427099
TCMC2362	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 1 (ug/ml), Ref: 20427099
TCMC2374	TCMT1251	Candida albicans	Candida albicans	IC50: 5 (ug/ml), Ref: 12502337
TCMC2374	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 7.5 (ug/ml), Ref: 12502337
TCMC2093	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 12932139
TCMC2093	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 12932139
TCMC737	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 26.9 (ug/ml), Ref: 15104496
TCMC737	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 35.8 (ug/ml), Ref: 15104496
TCMC737	TCMT1449	Influenza A virus	Influenza A virus	IC50: 24.5 (ug/ml), Ref: 15104496
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC2544	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.2 (ug/ml), Ref: 7964799
TCMC2544	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 50 (ug/ml), Ref: 7964799
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1955	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4.17 (ug/ml), Ref: 24549242
TCMC2228	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 18 (ug/ml), Ref: 18597896
TCMC2228	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 9 (ug/ml), Ref: 18597896
TCMC2228	TCMT1246	Escherichia coli	Escherichia coli	MIC: 16 (ug/ml), Ref: 18597896
TCMC2228	TCMT1251	Candida albicans	Candida albicans	MIC: 11 (ug/ml), Ref: 18597896
TCMC1551	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 20832915
TCMC2747	TCMT1182	Streptococcus sanguinis	Streptococcus sanguinis	MBC: 16 (ug/ml), Ref: 15958589 MIC: 16 (ug/ml), Ref: 15958589
TCMC2747	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MBC: 64 (ug/ml), Ref: 15958589 MIC: 32 (ug/ml), Ref: 15958589
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915
TCMC2818	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 64 (ug/ml), Ref: 20427099
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001