Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
---|---|---|---|---|
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TCMT156 | Cytochrome P450 19A1 | Homo sapiens |
IC50: 15 (nM), Ref: 20413308 |
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TCMT33 | Cytochrome P450 3A4 | Homo sapiens |
IC50: 9500 (nM), Ref: 15679319 Ki: 142 (nM), Ref: 16248836 |
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TCMT219 | Cytochrome P450 1A2 | Homo sapiens |
IC50: 2437 (nM), Ref: 20696580 |
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TCMT215 | Cytochrome P450 1A1 | Homo sapiens |
IC50: 140 (nM), Ref: 20696580 |
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TCMT257 | Cytochrome P450 1B1 | Homo sapiens |
IC50: 29 (nM), Ref: 20696580 |
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TCMT47 | Apoptosis regulator Bcl-2 | Homo sapiens |
Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5 |
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TCMT304 | Matrix metalloproteinase 14 | Homo sapiens |
IC50: 6800 (nM), Ref: 19524436 |
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TCMT306 | Matrix metalloproteinase-2 | Homo sapiens |
IC50: 9600 (nM), Ref: 19524436 |
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TCMT207 | Beta-secretase 1 | Homo sapiens |
IC50: 757 (nM), Ref: 22225636 |
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TCMT126 | Telomerase reverse transcriptase | Homo sapiens |
IC50: 1000 (nM), Ref: 22413845 IC50: 1080 (nM), Ref: 22413845 IC50: 1180 (nM), Ref: 22413845 IC50: 1000 (nM), Ref: 10.1039/C0MD00241K |
Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
---|---|---|---|---|
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TCMT1218 | Staphylococcus aureus | Staphylococcus aureus |
MIC: 15 (ug/ml), Ref: 11170636 |
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TCMT1218 | Staphylococcus aureus | Staphylococcus aureus |
MIC: 0.5 (ug/ml), Ref: 15863332 |
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TCMT1093 | Enoyl-acyl-carrier protein reductase | Plasmodium falciparum |
Ki: 16 (nM), Ref: 17263522 |
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TCMT1226 | Klebsiella pneumoniae | Klebsiella pneumoniae |
MIC: 100 (ug/ml), Ref: 10425115 |
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TCMT1465 | Entamoeba histolytica | Entamoeba histolytica |
IC50: 6.89 (ug/ml), Ref: 10.1007/s00044-011-9767-1 |
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TCMT1093 | Enoyl-acyl-carrier protein reductase | Plasmodium falciparum |
Ki: 17.56 (nM), Ref: 17263522 |
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TCMT1092 | Fatty acid synthase | Plasmodium falciparum |
IC50: 0.03 (ug/ml), Ref: 20855214 IC50: 30 (nM), Ref: 24063369 |
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TCMT1094 | 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum |
IC50: 0.32 (ug/ml), Ref: 20855214 |
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TCMT1093 | Enoyl-acyl-carrier protein reductase | Plasmodium falciparum |
Ki: 79 (nM), Ref: 17263522 Ki: 8 (nM), Ref: 17263522 |
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TCMT1222 | Plasmodium falciparum D6 | Plasmodium falciparum D6 |
IC50: 73 (nM), Ref: 25488841 |