Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC1187	TCMT151	Protein kinase C alpha	Homo sapiens	IC50: 1900 (nM), Ref: 9834166
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2195	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8
TCMC2195	TCMT335	Myeloperoxidase	Homo sapiens	IC50: 770 (nM), Ref: 23581551
TCMC2195	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1700 (nM), Ref: 22696418
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1965	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 452.6 (nM), Ref: 26498393
TCMC1965	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 515 (nM), Ref: 26498393
TCMC1411	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1261 (nM), Ref: 20696580
TCMC1411	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 56 (nM), Ref: 20696580
TCMC1411	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 17 (nM), Ref: 20696580
TCMC1411	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 212.9 (nM), Ref: 26498393
TCMC1411	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.4 (nM), Ref: 26498393
TCMC1411	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 54.9 (nM), Ref: 26498393 Ki: 220 (nM), Ref: 26498393
TCMC1411	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 440 (nM), Ref: 26498393
TCMC737	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 168 (nM), Ref: 26498393
TCMC737	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 5591.2 (nM), Ref: 26498393
TCMC737	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 423.7 (nM), Ref: 26498393
TCMC737	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4.9 (nM), Ref: 26498393
TCMC1735	TCMT599	Ubiquitin-conjugating enzyme E2 N	Homo sapiens	IC50: 8695 (nM), Ref: IC50: 5771 (nM), Ref: IC50: 6662 (nM), Ref:
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1399	TCMT223	Aldose reductase	Homo sapiens	IC50: 320 (nM), Ref: 22261024
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1409	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 5250 (nM), Ref: IC50: 8960 (nM), Ref:
TCMC1409	TCMT223	Aldose reductase	Homo sapiens	IC50: 4500 (nM), Ref: 22261024
TCMC1409	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 6211.2 (nM), Ref: 26498393 Ki: 410 (nM), Ref: 26498393
TCMC1409	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 75.7 (nM), Ref: 26498393
TCMC1409	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3.8 (nM), Ref: 26498393
TCMC1409	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.1 (nM), Ref: 26498393 Ki: 170 (nM), Ref: 26498393
TCMC910	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1118 (nM), Ref: 20696580
TCMC910	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 95 (nM), Ref: 20696580
TCMC910	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 20 (nM), Ref: 20696580
TCMC614	TCMT151	Protein kinase C alpha	Homo sapiens	IC50: 9300 (nM), Ref: 9834166
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC2196	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282
TCMC2196	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 150 (nM), Ref: 22819942
TCMC2196	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC983	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2800 (nM), Ref: 15887952 IC50: 2800 (nM), Ref: 15887952 IC50: 1200 (nM), Ref: 12502307 IC50: 2800 (nM), Ref:
TCMC983	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 7300 (nM), Ref: 21030469
TCMC983	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 718.7 (nM), Ref: 26498393
TCMC983	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.2 (nM), Ref: 26498393
TCMC983	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 56.4 (nM), Ref: 26498393
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1516	TCMT44	Glyoxalase I	Homo sapiens	IC50: 7700 (nM), Ref: 18258440
TCMC1516	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 3370 (nM), Ref: 20696580
TCMC1516	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1249 (nM), Ref: 20696580
TCMC1516	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 79 (nM), Ref: 20696580
TCMC1516	TCMT83	Lymphocyte differentiation antigen CD38	Homo sapiens	IC50: 8200 (nM), Ref: 21641214
TCMC1516	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 3610 (nM), Ref: 22658537
TCMC1516	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 5620 (nM), Ref: 22658537
TCMC1516	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 980 (nM), Ref: 22658537
TCMC1516	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1516	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 830 (nM), Ref: 23411073
TCMC1516	TCMT127	Poly [ADP-ribose] polymerase-1	Homo sapiens	IC50: 4265.8 (nM), Ref: 23574272 IC50: 4200 (nM), Ref: 23574272
TCMC1516	TCMT128	Tankyrase-2	Homo sapiens	IC50: 1071.52 (nM), Ref: 23574272 IC50: 1100 (nM), Ref: 23574272
TCMC1516	TCMT129	Tankyrase-1	Homo sapiens	IC50: 2398.83 (nM), Ref: 23574272 IC50: 2400 (nM), Ref: 23574272
TCMC1516	TCMT223	Aldose reductase	Homo sapiens	IC50: 600 (nM), Ref: 23683835 IC50: 3200 (nM), Ref: 26529431
TCMC1516	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1600 (nM), Ref: 24368208
TCMC1516	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 6400 (nM), Ref: 24878198
TCMC1516	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 2900 (nM), Ref: 25019478 IC50: 7800 (nM), Ref: 26096677
TCMC1516	TCMT100	Transthyretin	Homo sapiens	IC50: 7000 (nM), Ref: 26214366
TCMC1516	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3691.6 (nM), Ref: 26498393
TCMC1516	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.7 (nM), Ref: 26498393
TCMC1516	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 60.3 (nM), Ref: 26498393
TCMC1516	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 293 (nM), Ref: 26498393
TCMC1516	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 9200 (nM), Ref: 26529431
TCMC811	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	Ki: 2030 (nM), Ref: 19097799
TCMC811	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 9900 (nM), Ref: 18533708
TCMC811	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10.2 (nM), Ref: 20413308
TCMC811	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7078.5 (nM), Ref: 26498393
TCMC811	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 371.5 (nM), Ref: 26498393
TCMC811	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.5 (nM), Ref: 26498393
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC2201	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 8700 (nM), Ref: 21332115
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1236	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 10 (nM), Ref: 15341953 IC50: 10 (nM), Ref: 15456246 IC50: 98.7 (nM), Ref: 15887952 IC50: 98.7 (nM), Ref: 15887952 IC50: 9.7 (nM), Ref: 15943471 IC50: 10 (nM), Ref: 16098741 IC50: 1.3 (nM), Ref: 16219463 IC50: 61 (nM), Ref: 16610787 IC50: 25 (nM), Ref: 17149865 IC50: 395 (nM), Ref: 17049855 IC50: 9.7 (nM), Ref: 17188490 IC50: 6.8 (nM), Ref: 17574424 IC50: 18 (nM), Ref: 12502307 IC50: 98.7 (nM), Ref:
TCMC1236	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 395 (nM), Ref: 15341953 IC50: 395 (nM), Ref: 15456246 IC50: 4660 (nM), Ref: 15887952 IC50: 4660 (nM), Ref: 15887952 IC50: 395 (nM), Ref: 15943471 IC50: 395 (nM), Ref: 16098741 IC50: 29.4 (nM), Ref: 16219463 IC50: 1973 (nM), Ref: 16610787 IC50: 1145 (nM), Ref: 17149865 IC50: 2150 (nM), Ref: 17696335 IC50: 9.7 (nM), Ref: 17049855 IC50: 395 (nM), Ref: 17188490 IC50: 580 (nM), Ref: 17574424 IC50: 300 (nM), Ref: 12502307 IC50: 4680 (nM), Ref:
TCMC1236	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 10 (nM), Ref: 17482813
TCMC1236	TCMT910	Estrogen-related receptor beta	Homo sapiens	IC50: 395 (nM), Ref: 17482813
TCMC1236	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 2210 (nM), Ref: 18533708
TCMC1236	TCMT344	Aldehyde oxidase	Homo sapiens	IC50: 340 (nM), Ref: 20853847
TCMC1236	TCMT289	Thromboxane-A synthase	Homo sapiens	IC50: 7720 (nM), Ref:
TCMC950	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 75.7 (nM), Ref: 15887952 IC50: 75.7 (nM), Ref: 15887952 IC50: 75.7 (nM), Ref:
TCMC950	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 18.6 (nM), Ref: 15887952 IC50: 18.6 (nM), Ref: 15887952 IC50: 18.6 (nM), Ref:
TCMC2209	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 3400 (nM), Ref: 23388705 IC50: 5400 (nM), Ref: 23388705
TCMC2209	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 5200 (nM), Ref: 23388705 IC50: 5800 (nM), Ref: 23388705
TCMC710	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554
TCMC710	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 710 (nM), Ref: 18533708
TCMC710	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 800 (nM), Ref: 19414254
TCMC710	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5200 (nM), Ref: 19592245
TCMC710	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 795 (nM), Ref: 20696580
TCMC710	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 427 (nM), Ref: 20696580
TCMC710	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC710	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1450 (nM), Ref: 23411073
TCMC710	TCMT128	Tankyrase-2	Homo sapiens	IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272
TCMC710	TCMT129	Tankyrase-1	Homo sapiens	IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272
TCMC710	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844
TCMC710	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431
TCMC1064	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 2437 (nM), Ref: 20696580
TCMC1064	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 140 (nM), Ref: 20696580
TCMC1064	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 29 (nM), Ref: 20696580
TCMC674	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3850 (nM), Ref: 25497963
TCMC770	TCMT588	D-amino-acid oxidase	Homo sapiens	Ki: 7000 (nM), Ref: 23391306 IC50: 2089.3 (nM), Ref: 23631755 Ki: 2000 (nM), Ref: 23631755
TCMC1378	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 8960 (nM), Ref: 22658537
TCMC1378	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 8220 (nM), Ref: 22658537

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2257	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 15.46 (ug/ml), Ref: 20116898
TCMC2267	TCMT1107	Protease	Human immunodeficiency virus 1	IC50: 5 (ug/ml), Ref: 18547117 IC50: 5 (ug/ml), Ref: 19813754
TCMC1399	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1136	Neuraminidase	Influenza A virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1121	Sialidase	Clostridium perfringens	IC50: 11.28 (ug/ml), Ref: 21123068
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC983	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.43 (ug/ml), Ref: 20116898
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1516	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.65 (ug/ml), Ref: 20116898
TCMC1236	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 20.84 (ug/ml), Ref: 20116898
TCMC710	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 8.54 (ug/ml), Ref: 20116898
TCMC855	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 19299148
TCMC2354	TCMT1251	Candida albicans	Candida albicans	IC50: 81.47 (ug/ml), Ref: 25686593
TCMC1172	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC1172	TCMT1251	Candida albicans	Candida albicans	IC50: 2.82 (ug/ml), Ref: 11958988
TCMC1172	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 8 (ug/ml), Ref: 24641242
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC737	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 26.9 (ug/ml), Ref: 15104496
TCMC737	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 35.8 (ug/ml), Ref: 15104496
TCMC737	TCMT1449	Influenza A virus	Influenza A virus	IC50: 24.5 (ug/ml), Ref: 15104496
TCMC2432	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 12.5 (ug/ml), Ref: 10360733 MIC: 6.25 (ug/ml), Ref: 10360733
TCMC2257	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 37.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 59.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC2439	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 2 (ug/ml), Ref: 9784148
TCMC1399	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 62.5 (ug/ml), Ref: 18951808
TCMC1399	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.6 (ug/ml), Ref: 25137491
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC1409	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 94 (ug/ml), Ref: 15104489
TCMC1409	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 5.9 (ug/ml), Ref: 15104496
TCMC1409	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 23.4 (ug/ml), Ref: 15104496
TCMC1409	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 12762812
TCMC1409	TCMT1443	Leishmania amazonensis	Leishmania amazonensis	IC50: 0.78 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC614	TCMT1454	Bacillus subtilis	Bacillus subtilis	IC50: 98.5 (ug/ml), Ref: 25981688
TCMC2196	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 10 (ug/ml), Ref: 22819942 MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 1 (ug/ml), Ref: 23360475 MIC: 1 (ug/ml), Ref: 26253635
TCMC2196	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 6 (ug/ml), Ref: 26253635
TCMC1186	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 3430167
TCMC1186	TCMT1284	Penicillium expansum	Penicillium expansum	MIC: 50 (ug/ml), Ref: 3430167
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC924	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC2166	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 50 (ug/ml), Ref: 8864235
TCMC2166	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1321	Staphylococcus hominis	Staphylococcus hominis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906 MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1209	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1343	Staphylococcus simulans	Staphylococcus simulans	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1344	Staphylococcus sciuri	Staphylococcus sciuri	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC946	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 14510592
TCMC1516	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 64 (ug/ml), Ref: 12608861 MIC: 4 (ug/ml), Ref: 22677320
TCMC1516	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 18 (ug/ml), Ref: 22677320 MIC: 9 (ug/ml), Ref: 22677320
TCMC1516	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12608861
TCMC1516	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 7 (ug/ml), Ref: 17394331
TCMC1516	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 17.8 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1516	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1516	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 0.8 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC395	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC1776	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC1236	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2 (ug/ml), Ref: 19299148
TCMC1792	TCMT1227	Streptococcus	Streptococcus	MIC: 25 (ug/ml), Ref: 9182126
TCMC710	TCMT1246	Escherichia coli	Escherichia coli	MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC710	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC710	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1064	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 15 (ug/ml), Ref: 11170636
TCMC674	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 25 (ug/ml), Ref: 22280816
TCMC1047	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 50 (nM), Ref: 24549242