Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
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TCMT87 | Cytochrome P450 2C9 | Homo sapiens |
Ki: 6800 (nM), Ref: 22752007 |
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TCMT33 | Cytochrome P450 3A4 | Homo sapiens |
IC50: 10000 (nM), Ref: 14552748 IC50: 5620 (nM), Ref: 23033255 |
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TCMT112 | Adenosine A3 receptor | Homo sapiens |
Ki: 8290 (nM), Ref: 8917655 |
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TCMT778 | Voltage-gated potassium channel subunit Kv1.5 | Homo sapiens |
IC50: 6100 (nM), Ref: 19004630 |
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TCMT780 | Voltage-gated L-type calcium channel alpha-1D subunit | Homo sapiens |
IC50: 1350 (nM), Ref: 24754640 |
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TCMT725 | Voltage-gated L-type calcium channel alpha-1C subunit | Homo sapiens |
IC50: 22 (nM), Ref: 22761000 IC50: 55 (nM), Ref: 22761000 |
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TCMT219 | Cytochrome P450 1A2 | Homo sapiens |
IC50: 2300 (nM), Ref: 23033255 |
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TCMT31 | Cytochrome P450 2C19 | Homo sapiens |
IC50: 5420 (nM), Ref: 23033255 |
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TCMT87 | Cytochrome P450 2C9 | Homo sapiens |
IC50: 4080 (nM), Ref: 23033255 |
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TCMT220 | Cytochrome P450 2J2 | Homo sapiens |
IC50: 3060 (nM), Ref: 23033255 |
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TCMT407 | Myosin light chain kinase, smooth muscle | Homo sapiens |
IC50: 2020 (nM), Ref: 26385444 |
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TCMT38 | Dopamine D2 receptor | Homo sapiens |
Ki: 3900 (nM), Ref: 10.1016/S0960-894X(97)00194-7 |
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TCMT133 | Carbonic anhydrase I | Homo sapiens |
Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318 |
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TCMT136 | Carbonic anhydrase XII | Homo sapiens |
Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318 |
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TCMT141 | Carbonic anhydrase VA | Homo sapiens |
Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318 |
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TCMT135 | Carbonic anhydrase XIV | Homo sapiens |
Ki: 6160 (nM), Ref: 20185318 |
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TCMT137 | Carbonic anhydrase IX | Homo sapiens |
Ki: 3730 (nM), Ref: 20185318 |
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TCMT138 | Carbonic anhydrase VII | Homo sapiens |
Ki: 4080 (nM), Ref: 20185318 |
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TCMT139 | Carbonic anhydrase VI | Homo sapiens |
Ki: 5700 (nM), Ref: 20185318 |
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TCMT140 | Carbonic anhydrase VB | Homo sapiens |
Ki: 7130 (nM), Ref: 20185318 |
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TCMT142 | Carbonic anhydrase IV | Homo sapiens |
Ki: 7780 (nM), Ref: 20185318 |
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TCMT143 | Carbonic anhydrase III | Homo sapiens |
Ki: 6610 (nM), Ref: 20185318 |
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TCMT134 | Carbonic anhydrase II | Homo sapiens |
Ki: 870 (nM), Ref: 20185318 |
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TCMT254 | Carbonyl reductase [NADPH] 1 | Homo sapiens |
Ki: 3430 (nM), Ref: 19097799 |
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TCMT65 | Estradiol 17-beta-dehydrogenase 1 | Homo sapiens |
IC50: 4960 (nM), Ref: 18533708 |
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TCMT156 | Cytochrome P450 19A1 | Homo sapiens |
IC50: 2.9 (nM), Ref: 20413308 IC50: 230 (nM), Ref: 22115839 IC50: 230 (nM), Ref: 23142320 IC50: 1200 (nM), Ref: 23994869 IC50: 3300 (nM), Ref: 24074257 IC50: 1200 (nM), Ref: 24992702 IC50: 5100 (nM), Ref: 27155469 IC50: 1000 (nM), Ref: 27155469 |
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TCMT257 | Cytochrome P450 1B1 | Homo sapiens |
IC50: 3656 (nM), Ref: 20696580 |
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TCMT142 | Carbonic anhydrase IV | Homo sapiens |
Ki: 79.5 (nM), Ref: 26498393 |
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TCMT138 | Carbonic anhydrase VII | Homo sapiens |
Ki: 4.3 (nM), Ref: 26498393 |
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TCMT136 | Carbonic anhydrase XII | Homo sapiens |
Ki: 44.3 (nM), Ref: 26498393 |
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TCMT112 | Adenosine A3 receptor | Homo sapiens |
IC50: 1.77 (nM), Ref: 16250647 |
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TCMT675 | Beta-1 adrenergic receptor | Homo sapiens |
IC50: 600 (nM), Ref: 18983139 Ki: 430 (nM), Ref: 18983139 IC50: 1740 (nM), Ref: 18588282 IC50: 1640 (nM), Ref: 20875743 Ki: 170 (nM), Ref: 21726069 Ki: 150 (nM), Ref: 23466604 IC50: 260 (nM), Ref: 23466604 IC50: 210 (nM), Ref: 26988801 |
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TCMT423 | Epidermal growth factor receptor erbB1 | Homo sapiens |
IC50: 515 (nM), Ref: 12270171 IC50: 14.4 (nM), Ref: 16480284 IC50: 3.1 (nM), Ref: 16480284 IC50: 33 (nM), Ref: 16516473 IC50: 54 (nM), Ref: 16516473 IC50: 23 (nM), Ref: 16806916 IC50: 80 (nM), Ref: 16806916 IC50: 5.4 (nM), Ref: 17416531 IC50: 2753 (nM), Ref: 17416531 IC50: 22 (nM), Ref: 19170633 IC50: 33 (nM), Ref: 20304535 IC50: 70 (nM), Ref: 21353546 IC50: 1 (nM), Ref: 22101132 IC50: 1080 (nM), Ref: 22698782 IC50: 72 (nM), Ref: 22818848 IC50: 33 (nM), Ref: 23611691 IC50: 33 (nM), Ref: 23142066 IC50: 0.1 (nM), Ref: 23668441 IC50: 0.1 (nM), Ref: 23792318 IC50: 62 (nM), Ref: 23930994 IC50: 23 (nM), Ref: 23973168 IC50: 498 (nM), Ref: 23988354 IC50: 39.9 (nM), Ref: 23988354 IC50: 0.6 (nM), Ref: 23988354 IC50: 4000 (nM), Ref: 24900594 IC50: 1100 (nM), Ref: 24094432 IC50: 1 (nM), Ref: 24411123 IC50: 25 (nM), Ref: 24411123 IC50: 4000 (nM), Ref: 10.1039/C3MD00118K IC50: 70 (nM), Ref: 10.1039/C0MD00183J IC50: 1 (nM), Ref: 24588073 IC50: 0.1 (nM), Ref: 24607591 IC50: 20 (nM), Ref: 24731281 IC50: 0.45 (nM), Ref: 25468044 IC50: 0.45 (nM), Ref: 25462282 IC50: 76 (nM), Ref: 25409491 IC50: 380 (nM), Ref: 25768701 IC50: 1 (nM), Ref: 26275028 IC50: 26 (nM), Ref: 26256032 IC50: 22 (nM), Ref: 26318056 IC50: 1.3 (nM), Ref: 26706113 IC50: 22 (nM), Ref: 26451770 IC50: 13 (nM), Ref: 10.1039/C5MD00208G IC50: 15.5 (nM), Ref: 26829280 IC50: 11.8 (nM), Ref: 26879314 IC50: 2.6 (nM), Ref: 27234887 IC50: 0.509 (nM), Ref: 27288180 IC50: 127 (nM), Ref: 27288180 IC50: 76 (nM), Ref: 27387355 IC50: 0.585 (nM), Ref: 27132165 |
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TCMT704 | Receptor protein-tyrosine kinase erbB-2 | Homo sapiens |
IC50: 1604 (nM), Ref: 12270171 IC50: 343 (nM), Ref: 16480284 IC50: 599 (nM), Ref: 16480284 IC50: 280 (nM), Ref: 24411123 IC50: 1000 (nM), Ref: 25409491 IC50: 1830 (nM), Ref: 27132165 |
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TCMT747 | ATP-binding cassette sub-family G member 2 | Homo sapiens |
IC50: 3190 (nM), Ref: 24184213 |
