Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC159	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 2000 (nM), Ref: 22696418
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 3100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 1600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1871	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9200 (nM), Ref: 20185318 Ki: 9200 (nM), Ref: 20590092 Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9200 (nM), Ref: 23265898 Ki: 9200 (nM), Ref: 23010455 Ki: 9200 (nM), Ref: 24189056
TCMC1871	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8800 (nM), Ref: 20185318 Ki: 8800 (nM), Ref: 20590092 Ki: 8800 (nM), Ref: 20674354 Ki: 8800 (nM), Ref: 21282059 Ki: 8800 (nM), Ref: 23265898 Ki: 8800 (nM), Ref: 23010455 Ki: 8800 (nM), Ref: 24189056 Ki: 8800 (nM), Ref: 26520662
TCMC1871	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9500 (nM), Ref: 20185318 Ki: 9500 (nM), Ref: 20590092 Ki: 9500 (nM), Ref: 20674354 Ki: 9500 (nM), Ref: 23010455
TCMC1871	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 2700 (nM), Ref: 20185318 Ki: 2700 (nM), Ref: 20590092 Ki: 2700 (nM), Ref: 20674354 Ki: 2700 (nM), Ref: 23010455
TCMC1871	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 5500 (nM), Ref: 20185318 Ki: 5500 (nM), Ref: 20590092 Ki: 5500 (nM), Ref: 20674354 Ki: 5500 (nM), Ref: 21282059 Ki: 5500 (nM), Ref: 21332115 Ki: 5500 (nM), Ref: 23265898 Ki: 5500 (nM), Ref: 23265903 Ki: 5500 (nM), Ref: 23010455 Ki: 5500 (nM), Ref: 24189056 Ki: 5500 (nM), Ref: 26073005 Ki: 5500 (nM), Ref: 26520662
TCMC962	TCMT45	Beta amyloid A4 protein	Homo sapiens	Ki: 0.208 (nM), Ref: 17004725 IC50: 800 (nM), Ref: 17270435 IC50: 3900 (nM), Ref: 26099993
TCMC962	TCMT566	Nitric oxide synthase, inducible	Homo sapiens	IC50: 6000 (nM), Ref: 18077363
TCMC962	TCMT87	Cytochrome P450 2C9	Homo sapiens	IC50: 4300 (nM), Ref: 18249473
TCMC962	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 8500 (nM), Ref: 19128977
TCMC962	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2410 (nM), Ref: 20674354
TCMC962	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 380 (nM), Ref: 20674354
TCMC962	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4970 (nM), Ref: 20674354
TCMC962	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9460 (nM), Ref: 20674354
TCMC962	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 9940 (nM), Ref: 20674354
TCMC962	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 9300 (nM), Ref: 20674354
TCMC962	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4050 (nM), Ref: 20674354
TCMC962	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 3480 (nM), Ref: 20674354
TCMC962	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 6850 (nM), Ref: 20674354
TCMC962	TCMT44	Glyoxalase I	Homo sapiens	Ki: 10000 (nM), Ref: 21237663
TCMC962	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 7410 (nM), Ref:
TCMC962	TCMT46	Coagulation factor III	Homo sapiens	IC50: 199.63 (nM), Ref: 10.1007/s00044-012-0330-5 IC50: 199.63 (nM), Ref: 23199480
TCMC962	TCMT423	Epidermal growth factor receptor erbB1	Homo sapiens	IC50: 8600 (nM), Ref: 23245570
TCMC962	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 4501 (nM), Ref: 23800686
TCMC962	TCMT570	Aminopeptidase N	Homo sapiens	IC50: 10000 (nM), Ref: 23860593
TCMC962	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 3900 (nM), Ref: 24920381 IC50: 500 (nM), Ref: 24920381 IC50: 600 (nM), Ref: 24920381 IC50: 600 (nM), Ref: 24920381 IC50: 600 (nM), Ref: 24920381
TCMC962	TCMT164	Cyclooxygenase-1	Homo sapiens	IC50: 8100 (nM), Ref: 24920381
TCMC962	TCMT301	Prostaglandin E synthase	Homo sapiens	IC50: 600 (nM), Ref: 24920381 IC50: 1200 (nM), Ref: 24920381
TCMC962	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	IC50: 1200 (nM), Ref: 24920381
TCMC962	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5300 (nM), Ref: 25088549
TCMC962	TCMT565	Histone acetyltransferase p300	Homo sapiens	IC50: 6500 (nM), Ref: 25730130
TCMC2148	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 3200 (nM), Ref: 24920381
TCMC42	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 8390 (nM), Ref: 26696252
TCMC42	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2540 (nM), Ref: 26696252
TCMC43	TCMT301	Prostaglandin E synthase	Homo sapiens	IC50: 220 (nM), Ref: 26588603 IC50: 200 (nM), Ref: 10.1039/C5MD00278H
TCMC43	TCMT565	Histone acetyltransferase p300	Homo sapiens	IC50: 6500 (nM), Ref: 26701186
TCMC43	TCMT208	Monoamine oxidase A	Homo sapiens	Ki: 710 (nM), Ref: 26819666
TCMC43	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 3100 (nM), Ref: 27190601 IC50: 1500 (nM), Ref: 27190601
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC939	TCMT962	Autotaxin	Homo sapiens	Ki: 1890 (nM), Ref: 24387347 IC50: 1310 (nM), Ref: 16513348
TCMC249	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 257 (nM), Ref:
TCMC249	TCMT191	Signal transducer and activator of transcription 3	Homo sapiens	IC50: 6000 (nM), Ref: 19128055
TCMC249	TCMT34	Cytochrome P450 2D6	Homo sapiens	IC50: 600 (nM), Ref: 22206869
TCMC249	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 5200 (nM), Ref: IC50: 800 (nM), Ref:
TCMC1543	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 840 (nM), Ref: 16248836 Ki: 2500 (nM), Ref: 16248836

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC962	TCMT1104	Sortase	Staphylococcus aureus	IC50: 13.8 (ug/ml), Ref: 19269184
TCMC962	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 51.3 (ug/ml), Ref: 16643034
TCMC962	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 1 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC819	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 25 (ug/ml), Ref: 20691508
TCMC23	TCMT1251	Candida albicans	Candida albicans	MIC: 8 (ug/ml), Ref: 10.1021/np50053a042 MIC: 7.5 (ug/ml), Ref: 12444675
TCMC23	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 7.5 (ug/ml), Ref: 12444675
TCMC23	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 7.5 (ug/ml), Ref: 12444675
TCMC23	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	MIC: 3.6 (ug/ml), Ref: 12444675 MIC: 1.8 (ug/ml), Ref: 12444675
TCMC23	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	MIC: 3.6 (ug/ml), Ref: 12444675 MIC: 1.8 (ug/ml), Ref: 12444675
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2328	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 11473422 MIC: 32 (ug/ml), Ref: 11473422
TCMC2328	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 16 (ug/ml), Ref: 11473422
TCMC2328	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 11473422
TCMC2328	TCMT1246	Escherichia coli	Escherichia coli	MIC: 32 (ug/ml), Ref: 11473422
TCMC2328	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 32 (ug/ml), Ref: 11473422
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC1172	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC1172	TCMT1251	Candida albicans	Candida albicans	IC50: 2.82 (ug/ml), Ref: 11958988
TCMC1172	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 8 (ug/ml), Ref: 24641242
TCMC962	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 19299148 IC50: 3.5 (ug/ml), Ref: 19299148
TCMC962	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 4.2 (ug/ml), Ref: 19299148 IC50: 3.5 (ug/ml), Ref: 19299148
TCMC962	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 100 (ug/ml), Ref: 20691508
TCMC962	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 5 (ug/ml), Ref: 19204190 MIC: 15 (ug/ml), Ref: 19204190 MIC: 50 (ug/ml), Ref: 19204190 MIC: 30 (ug/ml), Ref: 19204190
TCMC962	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 30 (ug/ml), Ref: 18284200
TCMC962	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 25938986 MIC: 32 (ug/ml), Ref: 25938986
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC2402	TCMT1251	Candida albicans	Candida albicans	MIC: 31.25 (ug/ml), Ref: 8254344
TCMC2148	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 50 (ug/ml), Ref: 20691508
TCMC1322	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 100 (ug/ml), Ref: 20691508
TCMC2490	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 4 (ug/ml), Ref: 11975515
TCMC2496	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 100 (ug/ml), Ref: 20691508
TCMC1006	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 50 (ug/ml), Ref: 20691508
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550	TCMT1393	Vibrio sp.	Vibrio sp.	MIC: 15 (ug/ml), Ref: 21865038
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC924	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC899	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 52 (ug/ml), Ref: 22902032
TCMC899	TCMT1251	Candida albicans	Candida albicans	MIC: 0.5 (ug/ml), Ref: 23489634 MIC: 0.7 (ug/ml), Ref: 24044873
TCMC899	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.5 (ug/ml), Ref: 23489634 MIC: 1.3 (ug/ml), Ref: 24044873
TCMC899	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 1.7 (ug/ml), Ref: 24044873
TCMC899	TCMT1246	Escherichia coli	Escherichia coli	MIC: 0.5 (ug/ml), Ref: 24044873
TCMC1238	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC2760	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 19.8 (ug/ml), Ref: 18227183
TCMC1738	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC2815	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 1517735
TCMC2817	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 12.5 (ug/ml), Ref: 20691508
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001
TCMC962	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 10.2 (nM), Ref: 17503850
TCMC962	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 37 (nM), Ref: 20034711
TCMC962	TCMT1313	Human immunodeficiency virus 2	Human immunodeficiency virus type 2 (ISOLATE ROD)	IC50: 37 (nM), Ref: 20034711