Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1844	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 8400 (nM), Ref: 26035635
TCMC1844	TCMT510	Stem cell growth factor receptor	Homo sapiens	IC50: 600 (nM), Ref: 26807861 IC50: 1500 (nM), Ref: 26807861
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC1329	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2710 (nM), Ref: 26275107
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1147	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 410 (nM), Ref: 21167710
TCMC1064	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 2437 (nM), Ref: 20696580
TCMC1064	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 140 (nM), Ref: 20696580
TCMC1064	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 29 (nM), Ref: 20696580

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1329	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 13.9 (ug/ml), Ref: 20116898
TCMC2417	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25760525 MIC: 32 (ug/ml), Ref: 25760525
TCMC2417	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 25760525
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC2553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 12608857
TCMC2553	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 12608857
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC1329	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC2606	TCMT1248	Hepatitis C virus	Hepatitis C virus	IC50: 20 (ug/ml), Ref: 19904996
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2733	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 4 (ug/ml), Ref: 14698179
TCMC2734	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 15715470 MIC: 64 (ug/ml), Ref: MIC: 32 (ug/ml), Ref: 19179074
TCMC2735	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 8 (ug/ml), Ref: 15715470 MIC: 8 (ug/ml), Ref: 22194678 MIC: 8 (ug/ml), Ref: 19179074
TCMC2733	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 2 (ug/ml), Ref: 19179074 MIC: 4 (ug/ml), Ref: 16643039
TCMC2735	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17190457
TCMC2735	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 20405847
TCMC2733	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 4 (ug/ml), Ref: 12617583
TCMC2734	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 12617583
TCMC2734	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17438047
TCMC2735	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 17438047
TCMC2733	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 4 (ug/ml), Ref: 17438047
TCMC2772	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25856683 MIC: 8 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 16 (ug/ml), Ref: 15497933
TCMC2772	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 15679329
TCMC2772	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 18541727
TCMC2772	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref:
TCMC1064	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 15 (ug/ml), Ref: 11170636