Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC938	TCMT242	Histamine H3 receptor	Homo sapiens	Ki: 5.37 (nM), Ref: 18683917 Ki: 5.37 (nM), Ref: 18683917 Ki: 3.467 (nM), Ref: 18683917 Ki: 5.012 (nM), Ref: 18774720 Ki: 5.37 (nM), Ref: 19588934 Ki: 5.37 (nM), Ref: 19588934
TCMC938	TCMT243	Alpha-2c adrenergic receptor	Homo sapiens	Ki: 10.6 (nM), Ref: 18683917 Ki: 10.47 (nM), Ref: 18683917
TCMC938	TCMT247	Alpha-2a adrenergic receptor	Homo sapiens	Ki: 660.69 (nM), Ref: 18683917
TCMC1786	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3900 (nM), Ref: 16580200 IC50: 7600 (nM), Ref: 18798681 IC50: 4200 (nM), Ref: 19702283 IC50: 3840 (nM), Ref: 22044245 IC50: 5600 (nM), Ref: 22690646 IC50: 9500 (nM), Ref: 21453996 Ki: 6000 (nM), Ref: 21453996 IC50: 5050.1 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3370 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2600 (nM), Ref: 23357636 IC50: 1100 (nM), Ref: 23434422 IC50: 3020 (nM), Ref: 23942421 IC50: 2010 (nM), Ref: 24090912 IC50: 1900 (nM), Ref: 24684845 IC50: 3020 (nM), Ref: 25497963 IC50: 9500 (nM), Ref: 25264584 Ki: 6000 (nM), Ref: 25264584 IC50: 1030 (nM), Ref: 25595683 IC50: 1170 (nM), Ref: 25600405 IC50: 3020 (nM), Ref: 25872983 IC50: 1000 (nM), Ref: 26083682 IC50: 1536 (nM), Ref: 26100442 IC50: 700 (nM), Ref: 26115570 IC50: 700 (nM), Ref: 26253631 IC50: 1536 (nM), Ref: 26481657 IC50: 730 (nM), Ref: 26711144 IC50: 3020 (nM), Ref: 26774579 IC50: 1536 (nM), Ref: 27123900
TCMC1786	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 4000 (nM), Ref: 21561086 Ki: 3560 (nM), Ref: 21561086 Ki: 660 (nM), Ref: 21561086 Ki: 940 (nM), Ref: 21561086 Ki: 160 (nM), Ref: 21561086 Ki: 72 (nM), Ref: 21561086 IC50: 90 (nM), Ref: 21561086
TCMC1786	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 4230 (nM), Ref: 24684845 IC50: 4440 (nM), Ref: 25497963 IC50: 5460 (nM), Ref: 26100442 IC50: 5460 (nM), Ref: 26481657 IC50: 5460 (nM), Ref: 27123900
TCMC1786	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 980 (nM), Ref: 25497963
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC2209	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 3400 (nM), Ref: 23388705 IC50: 5400 (nM), Ref: 23388705
TCMC2209	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 5200 (nM), Ref: 23388705 IC50: 5800 (nM), Ref: 23388705
TCMC1297	TCMT632	Purine nucleoside phosphorylase	Homo sapiens	Ki: 5000 (nM), Ref: 31484

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1786	TCMT1107	Protease	Human immunodeficiency virus 1	IC50: 10 (ug/ml), Ref: 10691716
TCMC938	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 8.97 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC884	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC2401	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 20.9 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2411	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 16 (ug/ml), Ref: 11141098
TCMC2411	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 64 (ug/ml), Ref: 12608857
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC1786	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 21.8 (ug/ml), Ref: 9748372
TCMC1786	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC1786	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 11141098 MIC: 100 (ug/ml), Ref: 18798682 MIC: 64 (ug/ml), Ref: 15387646 MIC: 29 (ug/ml), Ref: 23356207
TCMC2452	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.87 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2473	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 3.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2481	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC2481	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268
TCMC2481	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 50 (ug/ml), Ref: 17027268
TCMC2481	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268
TCMC2481	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 17027268
TCMC2568	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 2.29 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2651	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2696	TCMT1354	Streptococcus mutans UA159	Streptococcus mutans UA159	MIC: 80 (ug/ml), Ref: 10.1007/s00044-011-9658-5