Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC1107	TCMT290	Muscarinic acetylcholine receptor M5	Homo sapiens	Ki: 0.14 (nM), Ref: 23707254 Ki: 0.3388 (nM), Ref: 24365159 Ki: 0.34 (nM), Ref: 24365159 Ki: 3.02 (nM), Ref: 25051097
TCMC1107	TCMT291	Muscarinic acetylcholine receptor M3	Homo sapiens	Ki: 0.2692 (nM), Ref: 24365159 Ki: 0.27 (nM), Ref: 24365159
TCMC1107	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 0.2692 (nM), Ref: 24365159 Ki: 0.27 (nM), Ref: 24365159
TCMC1107	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 5.012 (nM), Ref: 25051097 Ki: 12.88 (nM), Ref: 25051097 Ki: 3.631 (nM), Ref: 25051097 Ki: 2.818 (nM), Ref: 25051097
TCMC2195	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8
TCMC2195	TCMT335	Myeloperoxidase	Homo sapiens	IC50: 770 (nM), Ref: 23581551
TCMC2195	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1700 (nM), Ref: 22696418
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC2196	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282
TCMC2196	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 150 (nM), Ref: 22819942
TCMC2196	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220
TCMC1153	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7700 (nM), Ref: 22668600
TCMC1153	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8600 (nM), Ref: 22668600
TCMC1153	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 22668600
TCMC1153	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8700 (nM), Ref: 22668600
TCMC1153	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4800 (nM), Ref: 22668600
TCMC1153	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 7900 (nM), Ref: 22668600
TCMC2204	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 482 (nM), Ref: 21067924 Ki: 478 (nM), Ref: 22077347 Ki: 480 (nM), Ref: 26688270
TCMC2204	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 754 (nM), Ref: 22077347 Ki: 750 (nM), Ref: 26688270
TCMC1999	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 3.3 (nM), Ref: 8487254 Ki: 4.6 (nM), Ref: 8487254 Ki: 14 (nM), Ref: 8487254 Ki: 5.7 (nM), Ref: 8487254 Ki: 3.5 (nM), Ref: 8487254 Ki: 13 (nM), Ref: 8487254 Ki: 4.6 (nM), Ref: 8487254

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC2196	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 10 (ug/ml), Ref: 22819942 MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 1 (ug/ml), Ref: 23360475 MIC: 1 (ug/ml), Ref: 26253635
TCMC2196	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 6 (ug/ml), Ref: 26253635
TCMC2550	TCMT1393	Vibrio sp.	Vibrio sp.	MIC: 15 (ug/ml), Ref: 21865038