Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1609	TCMT44	Glyoxalase I	Homo sapiens	IC50: 560 (nM), Ref: 18258440 IC50: 560 (nM), Ref: 21669529
TCMC1609	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18778944
TCMC1609	TCMT737	DNA dC->dU-editing enzyme APOBEC-3G	Homo sapiens	IC50: 2390 (nM), Ref:
TCMC1609	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 2120 (nM), Ref: 24900447
TCMC1609	TCMT558	DNA topoisomerase II alpha	Homo sapiens	IC50: 390 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC1609	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2800 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1609	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1609	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1690 (nM), Ref: 23411073
TCMC1609	TCMT2	Microtubule-associated protein tau	Homo sapiens	IC50: 1200 (nM), Ref: 23484434 IC50: 3000 (nM), Ref: 25086914
TCMC1609	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC1609	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 3000 (nM), Ref: 25086914
TCMC1609	TCMT740	PI3-kinase p110-gamma subunit	Homo sapiens	IC50: 4720 (nM), Ref: 25050878
TCMC1609	TCMT13	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	IC50: 320 (nM), Ref: 25280182
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC732	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 5900 (nM), Ref: 21561086
TCMC1787	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3500 (nM), Ref: 18798681 IC50: 5320 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 5320 (nM), Ref: 10.1007/s00044-010-9529-5
TCMC998	TCMT154	Protein kinase C delta	Homo sapiens	Ki: 9.7 (nM), Ref: 23582444

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1609	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 26.29 (ug/ml), Ref: 20116898
TCMC2444	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 5.8 (ug/ml), Ref: 8786363 IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 5.8 (ug/ml), Ref: 8786363 IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 25372601
TCMC2454	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 19.6 (ug/ml), Ref: 10425115
TCMC1609	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 0.88 (ug/ml), Ref: 24749980
TCMC1609	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1609	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1609	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2576	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.24 (ug/ml), Ref: 8786363 IC50: 1.68 (ug/ml), Ref: 8786363
TCMC2576	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.24 (ug/ml), Ref: 8786363 IC50: 1.68 (ug/ml), Ref: 8786363
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC732	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 9 (ug/ml), Ref: 9748372
TCMC2035	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1787	TCMT1346	Helicobacter pylori	Helicobacter pylori	MBC: 0.292 (ug/ml), Ref: 17116667
TCMC1787	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 16 (ug/ml), Ref: 11141098
TCMC1787	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 0.8 (ug/ml), Ref: 9748372
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211