Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC795	TCMT223	Aldose reductase	Homo sapiens	IC50: 8000 (nM), Ref: 24341381
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC245	TCMT329	Quinone reductase 2	Homo sapiens	IC50: 3300 (nM), Ref: 21074425
TCMC1105	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 2000 (nM), Ref: 19414254
TCMC1105	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2500 (nM), Ref: 27173800
TCMC1356	TCMT223	Aldose reductase	Homo sapiens	IC50: 3000 (nM), Ref: 22261024
TCMC2018	TCMT907	Farnesyl diphosphate synthase	Homo sapiens	IC50: 452.9 (nM), Ref: 18327899 Ki: 82.2 (nM), Ref: 18327899 IC50: 5.7 (nM), Ref: 18327899 Ki: 0.36 (nM), Ref: 18327899 IC50: 5.7 (nM), Ref: 18434151 IC50: 300 (nM), Ref: 20801032 IC50: 11 (nM), Ref: 22390415 IC50: 860 (nM), Ref: 22390415 IC50: 11 (nM), Ref: 22884353 IC50: 10 (nM), Ref: 21780776 IC50: 5.2 (nM), Ref: 23998921 IC50: 11 (nM), Ref: 23998921 IC50: 6 (nM), Ref: 24911527 IC50: 11 (nM), Ref: 25630225 IC50: 6 (nM), Ref: 25935643 IC50: 0.36 (nM), Ref: 25815158 IC50: 82 (nM), Ref: 25815158
TCMC1701	TCMT158	Epoxide hydratase	Homo sapiens	Ki: 600 (nM), Ref: 19128055 IC50: 2200 (nM), Ref: 25052206

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC1356	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 64.6 (ug/ml), Ref: 9461665
TCMC795	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.6 (ug/ml), Ref: 15844943
TCMC2412	TCMT1348	Human rhinovirus 2	Human rhinovirus 2	IC50: 1 (ug/ml), Ref: 18247552
TCMC2425	TCMT1449	Influenza A virus	Influenza A virus	IC50: 0.51 (ug/ml), Ref: 19691312
TCMC2439	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 2 (ug/ml), Ref: 9784148
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1105	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 23534483
TCMC1105	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1 (ug/ml), Ref: 23534483
TCMC1105	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 23534483 MIC: 4 (ug/ml), Ref: 23534483
TCMC946	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 14510592
TCMC1356	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 32 (ug/ml), Ref: 21534606
TCMC1356	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 16 (ug/ml), Ref: 21534606
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2014	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 10 (ug/ml), Ref: 17220400
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2815	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 1517735
TCMC2018	TCMT1155	Farnesyl pyrophosphate synthase	Leishmania major	Ki: 17 (nM), Ref: 15828834