Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC903	TCMT175	G-protein coupled bile acid receptor 1	Homo sapiens	IC50: 6000 (nM), Ref: 20801037
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1758	TCMT247	Alpha-2a adrenergic receptor	Homo sapiens	Ki: 66 (nM), Ref: 8632424
TCMC1758	TCMT243	Alpha-2c adrenergic receptor	Homo sapiens	Ki: 63 (nM), Ref: 8632424
TCMC1758	TCMT559	Beta-2 adrenergic receptor	Homo sapiens	Ki: 3300 (nM), Ref: 27132867
TCMC1758	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 1300 (nM), Ref: 27132867
TCMC1477	TCMT273	Bile acid receptor FXR	Homo sapiens	IC50: 7860 (nM), Ref: 23688559
TCMC1477	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 5600 (nM), Ref: 21030469 IC50: 4900 (nM), Ref: 21030469
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1839	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9800 (nM), Ref: 18501600 Ki: 9800 (nM), Ref: 18579385 Ki: 920 (nM), Ref: 20185318
TCMC1839	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4800 (nM), Ref: 18579385 Ki: 6270 (nM), Ref: 20185318
TCMC1839	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 9200 (nM), Ref: 18579385 Ki: 3670 (nM), Ref: 20185318
TCMC1839	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6160 (nM), Ref: 20185318
TCMC1839	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 3730 (nM), Ref: 20185318
TCMC1839	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1839	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5700 (nM), Ref: 20185318
TCMC1839	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7130 (nM), Ref: 20185318
TCMC1839	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1839	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 6610 (nM), Ref: 20185318
TCMC1839	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 870 (nM), Ref: 20185318
TCMC453	TCMT588	D-amino-acid oxidase	Homo sapiens	Ki: 156 (nM), Ref: 23391306 IC50: 943 (nM), Ref: 23391306 IC50: 440 (nM), Ref: 23391306 IC50: 34.67 (nM), Ref: 23631755 Ki: 13 (nM), Ref: 23631755
TCMC1504	TCMT273	Bile acid receptor FXR	Homo sapiens	IC50: 18.3 (nM), Ref: 24775917
TCMC1498	TCMT864	Thyroid hormone receptor alpha	Homo sapiens	IC50: 0.24 (nM), Ref: 16099653 IC50: 0.24 (nM), Ref: 17543524 Ki: 0.33 (nM), Ref: 18975928 Ki: 2.33 (nM), Ref: 22542282 Ki: 2.33 (nM), Ref: 23276448 IC50: 3.2 (nM), Ref: 24290064
TCMC1498	TCMT69	Thyroid hormone receptor beta-1	Homo sapiens	IC50: 0.26 (nM), Ref: 16099653 IC50: 0.26 (nM), Ref: 17543524 IC50: 0.257 (nM), Ref: 17524652 Ki: 0.68 (nM), Ref: 18975928 Ki: 2.29 (nM), Ref: 22542282 Ki: 2.29 (nM), Ref: 23276448 IC50: 2.9 (nM), Ref: 24290064
TCMC1498	TCMT796	Proliferating cell nuclear antigen	Homo sapiens	IC50: 3600 (nM), Ref: 23395113

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC903	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 18805690
TCMC903	TCMT1246	Escherichia coli	Escherichia coli	MIC: 64 (ug/ml), Ref: 18805690 MIC: 7.81 (ug/ml), Ref: 20181416 MIC: 4 (ug/ml), Ref: 20038628 MIC: 8 (ug/ml), Ref: 20038628 MIC: 16 (ug/ml), Ref: 20038628
TCMC903	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 15.63 (ug/ml), Ref: 20181416
TCMC903	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 31.25 (ug/ml), Ref: 20181416
TCMC885	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.1 (ug/ml), Ref: 7381838 MIC: 0.8 (ug/ml), Ref: 7381838 MIC: 4 (ug/ml), Ref: 2933519 MIC: 1 (ug/ml), Ref: 2933519 MIC: 0.5 (ug/ml), Ref: 3373488 MIC: 0.5 (ug/ml), Ref: 2502627 MIC: 4 (ug/ml), Ref: 3877809 MIC: 4 (ug/ml), Ref: 2933520 MIC: 0.3 (ug/ml), Ref: 3701783 MIC: 20 (ug/ml), Ref: 2724308 MIC: 10 (ug/ml), Ref: 17825955 MIC: 8 (ug/ml), Ref: 19027993 MIC: 2 (ug/ml), Ref: 19027993 MIC: 4 (ug/ml), Ref: 19027993 MIC: 1 (ug/ml), Ref: 19027993 MIC: 4.6 (ug/ml), Ref: 20211890 MIC: 3.9 (ug/ml), Ref: 20211890 MIC: 2.5 (ug/ml), Ref: 20211890 MIC: 10.7 (ug/ml), Ref: 20211890 MIC: 3.1 (ug/ml), Ref: 20211890 MIC: 3.3 (ug/ml), Ref: 20211890 MIC: 3.8 (ug/ml), Ref: 20211890 MIC: 14.7 (ug/ml), Ref: 20211890 MIC: 6.6 (ug/ml), Ref: 20211890 MIC: 10.6 (ug/ml), Ref: 20211890 MIC: 1.25 (ug/ml), Ref: 894680 MIC: 5 (ug/ml), Ref: 894680 MIC: 1.25 (ug/ml), Ref: 894679 MIC: 5 (ug/ml), Ref: 894679 MIC: 1.6 (ug/ml), Ref: 392100 MIC: 6.2 (ug/ml), Ref: 392100 MIC: 4.5 (ug/ml), Ref: 21963
TCMC885	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1.6 (ug/ml), Ref: 7381838 MIC: 4 (ug/ml), Ref: 2933519 MIC: 0.5 (ug/ml), Ref: 3373488 MIC: 2 (ug/ml), Ref: 3877809 MIC: 2 (ug/ml), Ref: 2933520
TCMC885	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 25 (ug/ml), Ref: 7381838 MIC: 5 (ug/ml), Ref: 894680 MIC: 5 (ug/ml), Ref: 894679 MIC: 6.8 (ug/ml), Ref: 21963
TCMC885	TCMT1170	Enterobacter cloacae	Enterobacter cloacae	MIC: 25 (ug/ml), Ref: 7381838
TCMC885	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.2 (ug/ml), Ref: 7381838 MIC: 8 (ug/ml), Ref: 3373488 MIC: 1 (ug/ml), Ref: 3701783 MIC: 2 (ug/ml), Ref: 18180352 MIC: 12.5 (ug/ml), Ref: 894680 MIC: 12.5 (ug/ml), Ref: 894679 MIC: 6.2 (ug/ml), Ref: 392100 MIC: 8.5 (ug/ml), Ref: 21963
TCMC885	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 3.1 (ug/ml), Ref: 7381838 MIC: 16 (ug/ml), Ref: 3373488 MIC: 3.1 (ug/ml), Ref: 392100 MIC: 7 (ug/ml), Ref: 21963
TCMC885	TCMT1224	Proteus mirabilis	Proteus mirabilis	MIC: 12.5 (ug/ml), Ref: 7381838 MIC: 4 (ug/ml), Ref: 3373488 MIC: 6 (ug/ml), Ref: 18180352 MIC: 4 (ug/ml), Ref: 18180352 MIC: 3 (ug/ml), Ref: 18180352 MIC: 2 (ug/ml), Ref: 18180352 MIC: 1.5 (ug/ml), Ref: 18180352 MIC: 1 (ug/ml), Ref: 18180352 MIC: 12.5 (ug/ml), Ref: 894680 MIC: 12.5 (ug/ml), Ref: 894679 MIC: 25 (ug/ml), Ref: 392100
TCMC885	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 32 (ug/ml), Ref: 2933519 MIC: 32 (ug/ml), Ref: 3877809 MIC: 32 (ug/ml), Ref: 2933520 MIC: 12.5 (ug/ml), Ref: 392100
TCMC885	TCMT1177	Haemophilus influenzae	Haemophilus influenzae	MIC: 8 (ug/ml), Ref: 2933519 MIC: 4 (ug/ml), Ref: 3373488 MIC: 8 (ug/ml), Ref: 3877809 MIC: 8 (ug/ml), Ref: 2933520
TCMC885	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 32 (ug/ml), Ref: 3373488 MIC: 64 (ug/ml), Ref: 2502627 MIC: 64 (ug/ml), Ref: 19027993
TCMC885	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 1 (ug/ml), Ref: 3701783 MIC: 1 (ug/ml), Ref: 19027993
TCMC885	TCMT1194	Shigella sonnei	Shigella sonnei	MIC: 5 (ug/ml), Ref: 894680 MIC: 5 (ug/ml), Ref: 894679
TCMC885	TCMT1195	Streptococcus pasteurianus	Streptococcus pasteurianus	MIC: 1.6 (ug/ml), Ref: 392100
TCMC885	TCMT1196	Salmonella	Salmonella	MIC: 6.2 (ug/ml), Ref: 392100
TCMC885	TCMT1197	Shigella sp.	Shigella sp.	MIC: 9 (ug/ml), Ref: 21963
TCMC2417	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25760525 MIC: 32 (ug/ml), Ref: 25760525
TCMC2417	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 16 (ug/ml), Ref: 25760525
TCMC2417	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 25760525
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC495	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.33 (ug/ml), Ref: 8759172 IC50: 5.56 (ug/ml), Ref: 8759172
TCMC2606	TCMT1248	Hepatitis C virus	Hepatitis C virus	IC50: 20 (ug/ml), Ref: 19904996
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2733	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 4 (ug/ml), Ref: 14698179
TCMC2734	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 15715470 MIC: 64 (ug/ml), Ref: MIC: 32 (ug/ml), Ref: 19179074
TCMC2735	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 8 (ug/ml), Ref: 15715470 MIC: 8 (ug/ml), Ref: 22194678 MIC: 8 (ug/ml), Ref: 19179074
TCMC2733	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 2 (ug/ml), Ref: 19179074 MIC: 4 (ug/ml), Ref: 16643039
TCMC2735	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17190457
TCMC2735	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 20405847
TCMC2733	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 4 (ug/ml), Ref: 12617583
TCMC2734	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 12617583
TCMC2734	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: 17438047
TCMC2735	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 17438047
TCMC2733	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 4 (ug/ml), Ref: 17438047
TCMC2772	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 16 (ug/ml), Ref: 25856683 MIC: 8 (ug/ml), Ref: 10.6019/CHEMBL1201861 MIC: 16 (ug/ml), Ref: 15497933
TCMC2772	TCMT1187	Enterococcus faecalis ATCC 29212	Enterococcus faecalis ATCC 29212	MIC: 64 (ug/ml), Ref: 15679329
TCMC2772	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 8 (ug/ml), Ref: 18541727
TCMC2772	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 8 (ug/ml), Ref: