Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1211	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 270 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 270 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1211	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 750 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1211	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 2200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC908	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 6000 (nM), Ref: 15689157 IC50: 6000 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC908	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 2600 (nM), Ref: 15267241 IC50: 1 (nM), Ref: 20413308 IC50: 800 (nM), Ref: 10.1039/C3MD00166K IC50: 500 (nM), Ref: 26301554
TCMC908	TCMT223	Aldose reductase	Homo sapiens	IC50: 8500 (nM), Ref: 18165015
TCMC908	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	IC50: 670 (nM), Ref: 19097799 Ki: 110 (nM), Ref: 19097799
TCMC908	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 153 (nM), Ref: 20696580 IC50: 1290 (nM), Ref: 23600958
TCMC908	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 84 (nM), Ref: 20696580 IC50: 54 (nM), Ref: 20832301 IC50: 570 (nM), Ref: 23600958
TCMC908	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 24 (nM), Ref: 20696580
TCMC908	TCMT87	Cytochrome P450 2C9	Homo sapiens	IC50: 5225 (nM), Ref: 20832301
TCMC908	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5490 (nM), Ref: 22487176 Ki: 5420 (nM), Ref: 22487176
TCMC908	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4380 (nM), Ref: 22487176 Ki: 4310 (nM), Ref: 22487176
TCMC908	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 2650 (nM), Ref: 22487176 Ki: 2710 (nM), Ref: 22487176
TCMC908	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8960 (nM), Ref: 22487176 Ki: 9070 (nM), Ref: 22487176 Ki: 34.7 (nM), Ref: 26498393
TCMC908	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 537.75 (nM), Ref: 26498393
TCMC908	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 171.41 (nM), Ref: 26498393
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 3100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC715	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 1600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1086	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 36 (nM), Ref: 16005223 Ki: 3.3 (nM), Ref: 17531479 Ki: 36 (nM), Ref: 17919913 Ki: 41 (nM), Ref: 18522867 Ki: 36 (nM), Ref: 20621488 Ki: 36 (nM), Ref: 20943404 IC50: 9.5 (nM), Ref: 21999614 Ki: 24 (nM), Ref: 22284817 Ki: 36 (nM), Ref: 22341572 Ki: 71.6 (nM), Ref: 23679955 Ki: 71.6 (nM), Ref: 10.1039/C3MD00394A Ki: 36.4 (nM), Ref: 23865723 Ki: 46 (nM), Ref: 25072877 Ki: 42 (nM), Ref: 26000707
TCMC1086	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 17 (nM), Ref: 17531479 Ki: 2.9 (nM), Ref: 18522867 IC50: 2.8 (nM), Ref: 21999614 Ki: 10 (nM), Ref: 22284817 Ki: 3.88 (nM), Ref: 23679955 Ki: 3.88 (nM), Ref: 10.1039/C3MD00394A Ki: 40.7 (nM), Ref: 23865723 Ki: 22 (nM), Ref: 25072877 Ki: 18 (nM), Ref: 26000707
TCMC2068	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	IC50: 3270 (nM), Ref: 21902175 Ki: 750 (nM), Ref: 21902175
TCMC2068	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	IC50: 710 (nM), Ref: 21902175 Ki: 180 (nM), Ref: 21902175
TCMC2068	TCMT327	Vanilloid receptor	Homo sapiens	IC50: 5700 (nM), Ref: 21902175
TCMC1844	TCMT113	Delta opioid receptor	Homo sapiens	Ki: 8400 (nM), Ref: 26035635
TCMC1844	TCMT510	Stem cell growth factor receptor	Homo sapiens	IC50: 600 (nM), Ref: 26807861 IC50: 1500 (nM), Ref: 26807861
TCMC862	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	IC50: 3310 (nM), Ref: 21902175 Ki: 760 (nM), Ref: 21902175
TCMC862	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	IC50: 3460 (nM), Ref: 21902175 Ki: 880 (nM), Ref: 21902175
TCMC862	TCMT327	Vanilloid receptor	Homo sapiens	IC50: 2600 (nM), Ref: 21902175
TCMC880	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9910 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 20185318 Ki: 9900 (nM), Ref: 22245047 Ki: 9900 (nM), Ref: 26073005 Ki: 9900 (nM), Ref: 26520662
TCMC880	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 4200 (nM), Ref: 18579385 Ki: 4200 (nM), Ref: 20185318
TCMC880	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8900 (nM), Ref: 18579385 Ki: 8900 (nM), Ref: 20185318
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC606	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 251 (nM), Ref: 20696580
TCMC606	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 86 (nM), Ref: 20696580
TCMC606	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 12 (nM), Ref: 20696580
TCMC755	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	Ki: 600 (nM), Ref: 21739938
TCMC755	TCMT81	Arachidonate 12-lipoxygenase	Homo sapiens	Ki: 1600 (nM), Ref: 21739938
TCMC755	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC755	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 4400 (nM), Ref: 21030469 IC50: 7000 (nM), Ref: 21030469
TCMC755	TCMT384	G protein-coupled receptor kinase 6	Homo sapiens	IC50: 8700 (nM), Ref:
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1516	TCMT44	Glyoxalase I	Homo sapiens	IC50: 7700 (nM), Ref: 18258440
TCMC1516	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 3370 (nM), Ref: 20696580
TCMC1516	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1249 (nM), Ref: 20696580
TCMC1516	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 79 (nM), Ref: 20696580
TCMC1516	TCMT83	Lymphocyte differentiation antigen CD38	Homo sapiens	IC50: 8200 (nM), Ref: 21641214
TCMC1516	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 3610 (nM), Ref: 22658537
TCMC1516	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 5620 (nM), Ref: 22658537
TCMC1516	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 980 (nM), Ref: 22658537
TCMC1516	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1516	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 830 (nM), Ref: 23411073
TCMC1516	TCMT127	Poly [ADP-ribose] polymerase-1	Homo sapiens	IC50: 4265.8 (nM), Ref: 23574272 IC50: 4200 (nM), Ref: 23574272
TCMC1516	TCMT128	Tankyrase-2	Homo sapiens	IC50: 1071.52 (nM), Ref: 23574272 IC50: 1100 (nM), Ref: 23574272
TCMC1516	TCMT129	Tankyrase-1	Homo sapiens	IC50: 2398.83 (nM), Ref: 23574272 IC50: 2400 (nM), Ref: 23574272
TCMC1516	TCMT223	Aldose reductase	Homo sapiens	IC50: 600 (nM), Ref: 23683835 IC50: 3200 (nM), Ref: 26529431
TCMC1516	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1600 (nM), Ref: 24368208
TCMC1516	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 6400 (nM), Ref: 24878198
TCMC1516	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 2900 (nM), Ref: 25019478 IC50: 7800 (nM), Ref: 26096677
TCMC1516	TCMT100	Transthyretin	Homo sapiens	IC50: 7000 (nM), Ref: 26214366
TCMC1516	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3691.6 (nM), Ref: 26498393
TCMC1516	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.7 (nM), Ref: 26498393
TCMC1516	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 60.3 (nM), Ref: 26498393
TCMC1516	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 293 (nM), Ref: 26498393
TCMC1516	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 9200 (nM), Ref: 26529431
TCMC1798	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1480 (nM), Ref: 23411073
TCMC1606	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 56 (nM), Ref: 10891110
TCMC1606	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 25 (nM), Ref: 10891110 Ki: 72 (nM), Ref: 10891110 Ki: 75 (nM), Ref: 9622546 IC50: 449 (nM), Ref: 9622546 IC50: 3900 (nM), Ref: 9622546 Ki: 489.78 (nM), Ref: 18182302
TCMC1606	TCMT551	Muscarinic acetylcholine receptor M4	Homo sapiens	Ki: 1400 (nM), Ref: 10891110 Ki: 23 (nM), Ref: 10891110
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC861	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 10000 (nM), Ref: 20218623 Ki: 2860 (nM), Ref: 23865723
TCMC861	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 2400 (nM), Ref: 20218623 Ki: 4350 (nM), Ref: 23865723
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1320	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 2786 (nM), Ref: 20696580
TCMC1320	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 511 (nM), Ref: 20696580
TCMC1320	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 102.1 (nM), Ref: 26498393
TCMC1320	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3.3 (nM), Ref: 26498393
TCMC1320	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 454.1 (nM), Ref: 26498393
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1662	TCMT314	Serotonin 2c (5-HT2c) receptor	Homo sapiens	Ki: 10 (nM), Ref: 24491146
TCMC1682	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 30 (nM), Ref: 25282650
TCMC1683	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 3274 (nM), Ref: 25282650
TCMC592	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 3219 (nM), Ref: 25218910
TCMC594	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 88 (nM), Ref: 25218910
TCMC1686	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 912 (nM), Ref: 25173852
TCMC863	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 2143 (nM), Ref: 25218910
TCMC1684	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 129 (nM), Ref: 25218910
TCMC1685	TCMT114	Cannabinoid CB2 receptor	Homo sapiens	Ki: 335 (nM), Ref: 25218910
TCMC1685	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 224 (nM), Ref: 19969457
TCMC1684	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 117 (nM), Ref: 19969457
TCMC863	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 5668 (nM), Ref: 19969457
TCMC1686	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 47 (nM), Ref: 19969457
TCMC594	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 65 (nM), Ref: 19969457
TCMC592	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 1906 (nM), Ref: 19969457
TCMC1683	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 830 (nM), Ref: 19969457
TCMC1682	TCMT115	Cannabinoid CB1 receptor	Homo sapiens	Ki: 31 (nM), Ref: 19969457
TCMC710	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554
TCMC710	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 710 (nM), Ref: 18533708
TCMC710	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 800 (nM), Ref: 19414254
TCMC710	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5200 (nM), Ref: 19592245
TCMC710	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 795 (nM), Ref: 20696580
TCMC710	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 427 (nM), Ref: 20696580
TCMC710	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC710	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1450 (nM), Ref: 23411073
TCMC710	TCMT128	Tankyrase-2	Homo sapiens	IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272
TCMC710	TCMT129	Tankyrase-1	Homo sapiens	IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272
TCMC710	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844
TCMC710	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431
TCMC2216	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3600 (nM), Ref: 17489632 IC50: 3100 (nM), Ref: 18798681 IC50: 3600 (nM), Ref: 19008110 IC50: 3600 (nM), Ref: 17125223 IC50: 3800 (nM), Ref: 19846295 IC50: 3900 (nM), Ref: 19632832 IC50: 3600 (nM), Ref: 19836230 IC50: 3100 (nM), Ref: 21555221 IC50: 3600 (nM), Ref: 21571537 IC50: 3100 (nM), Ref: 22940448 IC50: 2300 (nM), Ref: 21453996 Ki: 3400 (nM), Ref: 21453996 IC50: 3600 (nM), Ref: 23022281 IC50: 3080 (nM), Ref: 23141910 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 3080 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 2750 (nM), Ref: 23387824 IC50: 4120 (nM), Ref: 24224843 IC50: 4000 (nM), Ref: 24953600 IC50: 3500 (nM), Ref: 25559759 IC50: 3400 (nM), Ref: 25907369 Ki: 6400 (nM), Ref: 25907369 IC50: 5200 (nM), Ref: 26841168
TCMC2216	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 1900 (nM), Ref: 20100662
TCMC2216	TCMT102	Low molecular weight phosphotyrosine protein phosphatase	Homo sapiens	IC50: 7200 (nM), Ref: 21453996
TCMC2216	TCMT103	Receptor-type tyrosine-protein phosphatase F (LAR)	Homo sapiens	IC50: 3800 (nM), Ref: 21453996
TCMC2216	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 21561086 Ki: 3700 (nM), Ref: 21561086 Ki: 2100 (nM), Ref: 21561086 Ki: 2800 (nM), Ref: 21561086 Ki: 2000 (nM), Ref: 21561086 IC50: 4000 (nM), Ref: 21561086
TCMC2216	TCMT190	T-cell protein-tyrosine phosphatase	Homo sapiens	IC50: 2400 (nM), Ref: 23387824
TCMC2216	TCMT150	Nuclear receptor ROR-gamma	Homo sapiens	IC50: 680 (nM), Ref: 10.1039/C3MD00005B IC50: 130 (nM), Ref: 24704616 IC50: 1060 (nM), Ref: 24704616 IC50: 9410 (nM), Ref: 24704616

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC908	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 11.62 (ug/ml), Ref: 20116898
TCMC2233	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 20.85 (ug/ml), Ref: 20116898
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1516	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.65 (ug/ml), Ref: 20116898
TCMC710	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 8.54 (ug/ml), Ref: 20116898
TCMC2313	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC908	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 11170636 MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1086	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 18681481 MIC: 1 (ug/ml), Ref: 18681481 MIC: 0.5 (ug/ml), Ref: 18681481
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC2237	TCMT1464	Hepatitis B virus	Hepatitis B virus	IC50: 4 (ug/ml), Ref: 24549242
TCMC2449	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1 (ug/ml), Ref: 18681481
TCMC2451	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 8 (ug/ml), Ref: 18681481 MIC: 4 (ug/ml), Ref: 18681481
TCMC2481	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC2481	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268
TCMC2481	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 50 (ug/ml), Ref: 17027268
TCMC2481	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268
TCMC2481	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 12.5 (ug/ml), Ref: 17027268
TCMC1767	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 60 (ug/ml), Ref: 20384293
TCMC1767	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC862	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1 (ug/ml), Ref: 18681481 MIC: 2 (ug/ml), Ref: 18681481
TCMC60	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2549	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 18681481 MIC: 1 (ug/ml), Ref: 18681481
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC606	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 5.5 (ug/ml), Ref: 19299148
TCMC755	TCMT1251	Candida albicans	Candida albicans	IC50: 6 (ug/ml), Ref: 12502337
TCMC755	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC755	TCMT1249	Dengue virus 2	Dengue virus 2	IC50: 6.46 (ug/ml), Ref: 25564380
TCMC2166	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 50 (ug/ml), Ref: 8864235
TCMC2166	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1321	Staphylococcus hominis	Staphylococcus hominis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906 MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1209	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1343	Staphylococcus simulans	Staphylococcus simulans	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1344	Staphylococcus sciuri	Staphylococcus sciuri	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1516	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 64 (ug/ml), Ref: 12608861 MIC: 4 (ug/ml), Ref: 22677320
TCMC1516	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 18 (ug/ml), Ref: 22677320 MIC: 9 (ug/ml), Ref: 22677320
TCMC1516	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12608861
TCMC1516	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 7 (ug/ml), Ref: 17394331
TCMC1516	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 17.8 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1516	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1516	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 0.8 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2644	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 6.25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2669	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 18681481
TCMC2671	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC2671	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC861	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1 (ug/ml), Ref: 18681481 MIC: 0.5 (ug/ml), Ref: 18681481
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC2701	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 18681481 MIC: 2 (ug/ml), Ref: 18681481
TCMC2732	TCMT1251	Candida albicans	Candida albicans	IC50: 8.5 (ug/ml), Ref: 20566771
TCMC2732	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.7 (ug/ml), Ref: 20566771 IC50: 2.4 (ug/ml), Ref: 18519714
TCMC710	TCMT1246	Escherichia coli	Escherichia coli	MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC710	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC710	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2216	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 6.5 (ug/ml), Ref: 9748372
TCMC2216	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 100 (ug/ml), Ref: 20542692
TCMC2216	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 21288041
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001