Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
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TCMT174 | 11-beta-hydroxysteroid dehydrogenase 1 | Homo sapiens |
IC50: 810 (nM), Ref: 20100662 |
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TCMT101 | Protein-tyrosine phosphatase 1B | Homo sapiens |
IC50: 7000 (nM), Ref: 22940448 IC50: 5490 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 5490 (nM), Ref: 10.1007/s00044-010-9529-5 |
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TCMT301 | Prostaglandin E synthase | Homo sapiens |
IC50: 5000 (nM), Ref: 24844534 |
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TCMT203 | Glucose-6-phosphate 1-dehydrogenase | Homo sapiens |
Ki: 3400 (nM), Ref: 19231202 Ki: 3000 (nM), Ref: 19231202 IC50: 9400 (nM), Ref: 22506561 |
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TCMT101 | Protein-tyrosine phosphatase 1B | Homo sapiens |
IC50: 8040 (nM), Ref: 10.1007/s00044-010-9529-5 IC50: 8040 (nM), Ref: 10.1007/s00044-010-9529-5 |
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TCMT301 | Prostaglandin E synthase | Homo sapiens |
IC50: 3000 (nM), Ref: 24844534 |
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TCMT230 | Estradiol 17-beta-dehydrogenase 3 | Homo sapiens |
IC50: 330 (nM), Ref: 11086723 IC50: 330 (nM), Ref: 16078844 |
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TCMT807 | Solute carrier family 22 member 12 | Homo sapiens |
IC50: 2000 (nM), Ref: 17325024 Ki: 5740 (nM), Ref: 17325024 |
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TCMT236 | Estrogen receptor beta | Homo sapiens | IC50: 2927.18 (nM), Ref: |
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TCMT61 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens | IC50: 2988.26 (nM), Ref: |
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TCMT739 | G-protein coupled receptor 35 | Homo sapiens |
IC50: 1600 (nM), Ref: 24900447 |
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TCMT261 | Death-associated protein kinase 1 | Homo sapiens |
IC50: 1600 (nM), Ref: 26322379 |
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TCMT283 | Receptor-type tyrosine-protein phosphatase S | Homo sapiens |
IC50: 4300 (nM), Ref: 26602279 |
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TCMT297 | Fatty acid binding protein adipocyte | Homo sapiens |
IC50: 930 (nM), Ref: 15357969 |
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TCMT298 | Fatty acid binding protein muscle | Homo sapiens |
IC50: 2600 (nM), Ref: 15357969 |
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TCMT808 | Fatty acid binding protein epidermal | Homo sapiens |
IC50: 1200 (nM), Ref: 15357969 |
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TCMT809 | Fatty acid binding protein intestinal | Homo sapiens |
IC50: 1700 (nM), Ref: 15357969 |
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TCMT810 | Toll-like receptor 2 | Homo sapiens |
IC50: 5000 (nM), Ref: 16509590 |
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TCMT64 | Peroxisome proliferator-activated receptor delta | Homo sapiens |
IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6 |
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TCMT63 | Peroxisome proliferator-activated receptor alpha | Homo sapiens |
IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6 |
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TCMT219 | Cytochrome P450 1A2 | Homo sapiens |
IC50: 251 (nM), Ref: 20696580 |
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TCMT215 | Cytochrome P450 1A1 | Homo sapiens |
IC50: 86 (nM), Ref: 20696580 |
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TCMT257 | Cytochrome P450 1B1 | Homo sapiens |
IC50: 12 (nM), Ref: 20696580 |
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TCMT301 | Prostaglandin E synthase | Homo sapiens |
IC50: 1100 (nM), Ref: 24844534 |
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TCMT215 | Cytochrome P450 1A1 | Homo sapiens |
IC50: 7906 (nM), Ref: 20696580 |
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TCMT257 | Cytochrome P450 1B1 | Homo sapiens |
IC50: 1679 (nM), Ref: 20696580 |
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TCMT219 | Cytochrome P450 1A2 | Homo sapiens |
IC50: 1491 (nM), Ref: 20696580 |
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TCMT156 | Cytochrome P450 19A1 | Homo sapiens |
IC50: 900 (nM), Ref: 10.1039/C3MD00166K |
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TCMT280 | Aldo-keto reductase family 1 member B10 | Homo sapiens |
IC50: 5900 (nM), Ref: 21561086 |
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TCMT187 | Androgen Receptor | Homo sapiens |
Ki: 8.5 (nM), Ref: 12954062 IC50: 37 (nM), Ref: 12954062 IC50: 37 (nM), Ref: 12781197 IC50: 37 (nM), Ref: 8627601 Ki: 8.5 (nM), Ref: 8627601 Ki: 8.5 (nM), Ref: 9873735 IC50: 37 (nM), Ref: 9784110 Ki: 35 (nM), Ref: 20510622 |
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TCMT613 | Glucocorticoid receptor | Homo sapiens |
Ki: 30.5 (nM), Ref: 12954062 Ki: 30.5 (nM), Ref: 9873735 Ki: 30.5 (nM), Ref: 9784110 |
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TCMT783 | Mineralocorticoid receptor | Homo sapiens |
IC50: 14 (nM), Ref: 12954062 IC50: 14 (nM), Ref: 12781197 IC50: 14 (nM), Ref: 9784110 IC50: 30 (nM), Ref: 8709117 |
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TCMT904 | Progesterone receptor | Homo sapiens |
Ki: 3.5 (nM), Ref: 10212133 IC50: 3.5 (nM), Ref: 11859003 Ki: 3.5 (nM), Ref: 9464361 IC50: 5 (nM), Ref: 8523399 Ki: 3.8 (nM), Ref: 9667968 Ki: 3.467 (nM), Ref: 16821785 Ki: 3.4 (nM), Ref: 18553958 Ki: 5.1 (nM), Ref: 20510622 |
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TCMT907 | Farnesyl diphosphate synthase | Homo sapiens |
IC50: 452.9 (nM), Ref: 18327899 Ki: 82.2 (nM), Ref: 18327899 IC50: 5.7 (nM), Ref: 18327899 Ki: 0.36 (nM), Ref: 18327899 IC50: 5.7 (nM), Ref: 18434151 IC50: 300 (nM), Ref: 20801032 IC50: 11 (nM), Ref: 22390415 IC50: 860 (nM), Ref: 22390415 IC50: 11 (nM), Ref: 22884353 IC50: 10 (nM), Ref: 21780776 IC50: 5.2 (nM), Ref: 23998921 IC50: 11 (nM), Ref: 23998921 IC50: 6 (nM), Ref: 24911527 IC50: 11 (nM), Ref: 25630225 IC50: 6 (nM), Ref: 25935643 IC50: 0.36 (nM), Ref: 25815158 IC50: 82 (nM), Ref: 25815158 |
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TCMT82 | Estrogen receptor alpha | Homo sapiens |
IC50: 1.3 (nM), Ref: 15203155 IC50: 3 (nM), Ref: 10673099 IC50: 1.3 (nM), Ref: 15203156 Ki: 100 (nM), Ref: 12954056 IC50: 2 (nM), Ref: 12749898 IC50: 5.9 (nM), Ref: 10447957 IC50: 1.3 (nM), Ref: 15745820 IC50: 1.3 (nM), Ref: 15664843 IC50: 1.3 (nM), Ref: 15582421 IC50: 1.3 (nM), Ref: 15225685 IC50: 1.3 (nM), Ref: 15225686 IC50: 3.2 (nM), Ref: 15341953 IC50: 3.2 (nM), Ref: 15456246 IC50: 3.2 (nM), Ref: 15876535 IC50: 3.2 (nM), Ref: 15943471 IC50: 28 (nM), Ref: 15658851 Ki: 1.995 (nM), Ref: 15771467 IC50: 3.2 (nM), Ref: 16098741 IC50: 0.75 (nM), Ref: 16219463 IC50: 1.4 (nM), Ref: 16309907 IC50: 1.35 (nM), Ref: 16412638 IC50: 10 (nM), Ref: 16610787 IC50: 1.3 (nM), Ref: 16632357 IC50: 1.3 (nM), Ref: 16730987 IC50: 46 (nM), Ref: 16942012 IC50: 1.6 (nM), Ref: 16942012 IC50: 1.3 (nM), Ref: 16777408 IC50: 1.2 (nM), Ref: 17149865 IC50: 4.7 (nM), Ref: 17696335 IC50: 3.6 (nM), Ref: 17049855 IC50: 3.2 (nM), Ref: 17188490 IC50: 1 (nM), Ref: 17289385 IC50: 1.4 (nM), Ref: 17448656 IC50: 1.4 (nM), Ref: 17890084 IC50: 4 (nM), Ref: 18760603 Ki: 2 (nM), Ref: 18722117 IC50: 12.5 (nM), Ref: 19836949 IC50: 3.2 (nM), Ref: 19705860 Ki: 0.16 (nM), Ref: 20621492 IC50: 21.04 (nM), Ref: 20812681 IC50: 46 (nM), Ref: 20875743 IC50: 1.3 (nM), Ref: 24315190 IC50: 5.7 (nM), Ref: 25369367 IC50: 0.9 (nM), Ref: 26183544 Ki: 0.21 (nM), Ref: Ki: 0.21 (nM), Ref: IC50: 1.7 (nM), Ref: 27407030 |
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TCMT236 | Estrogen receptor beta | Homo sapiens |
IC50: 1.1 (nM), Ref: 15203155 IC50: 4 (nM), Ref: 10673099 IC50: 1.1 (nM), Ref: 15203156 Ki: 100 (nM), Ref: 12954056 IC50: 2 (nM), Ref: 12749898 IC50: 1.1 (nM), Ref: 15745820 IC50: 1.1 (nM), Ref: 15664843 IC50: 1.1 (nM), Ref: 15993065 IC50: 1.1 (nM), Ref: 15582421 IC50: 1.1 (nM), Ref: 15225685 IC50: 1.1 (nM), Ref: 15225686 IC50: 3.6 (nM), Ref: 15341953 IC50: 3.6 (nM), Ref: 15456246 IC50: 3.6 (nM), Ref: 15876535 IC50: 3.6 (nM), Ref: 15943471 IC50: 24 (nM), Ref: 15658851 Ki: 3.162 (nM), Ref: 15771467 IC50: 3.6 (nM), Ref: 16098741 IC50: 1.18 (nM), Ref: 16219463 IC50: 1.2 (nM), Ref: 16309907 IC50: 1.2 (nM), Ref: 16412638 IC50: 11 (nM), Ref: 16610787 IC50: 1.2 (nM), Ref: 16632357 IC50: 1.2 (nM), Ref: 16730987 IC50: 1.4 (nM), Ref: 16942012 IC50: 1.1 (nM), Ref: 16777408 IC50: 1.4 (nM), Ref: 17149865 IC50: 16.7 (nM), Ref: 17696335 IC50: 3.2 (nM), Ref: 17049855 IC50: 3.6 (nM), Ref: 17188490 IC50: 1 (nM), Ref: 17289385 IC50: 1.2 (nM), Ref: 17448656 IC50: 1.2 (nM), Ref: 17890084 IC50: 4 (nM), Ref: 18760603 Ki: 2 (nM), Ref: 18722117 IC50: 2.9 (nM), Ref: 19705860 IC50: 10.74 (nM), Ref: 20812681 IC50: 0.046 (nM), Ref: 24315190 IC50: 5.6 (nM), Ref: 25369367 Ki: 0.015 (nM), Ref: Ki: 0.015 (nM), Ref: IC50: 3 (nM), Ref: 27407030 |
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TCMT187 | Androgen Receptor | Homo sapiens |
IC50: 19.1 (nM), Ref: 16309907 |
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TCMT99 | Testis-specific androgen-binding protein | Homo sapiens |
IC50: 50 (nM), Ref: 17149875 |
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TCMT591 | Estrogen-related receptor alpha | Homo sapiens |
IC50: 3.6 (nM), Ref: 17482813 IC50: 6 (nM), Ref: 23448346 |
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TCMT910 | Estrogen-related receptor beta | Homo sapiens |
IC50: 3.2 (nM), Ref: 17482813 IC50: 8.7 (nM), Ref: 23448346 |
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TCMT344 | Aldehyde oxidase | Homo sapiens |
IC50: 80 (nM), Ref: 20853847 Ki: 4400 (nM), Ref: 22996261 Ki: 870 (nM), Ref: 22996261 |
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TCMT974 | G-protein coupled estrogen receptor 1 | Homo sapiens |
Ki: 5.7 (nM), Ref: 23672690 Ki: 2.7 (nM), Ref: 10.1039/C5MD00455A |
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TCMT249 | Cyclin-dependent kinase 6 | Homo sapiens |
IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5 |
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TCMT156 | Cytochrome P450 19A1 | Homo sapiens |
IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554 |
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TCMT65 | Estradiol 17-beta-dehydrogenase 1 | Homo sapiens |
IC50: 710 (nM), Ref: 18533708 |
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TCMT752 | Casein kinase II alpha | Homo sapiens |
IC50: 800 (nM), Ref: 19414254 |
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TCMT187 | Androgen Receptor | Homo sapiens |
IC50: 5200 (nM), Ref: 19592245 |
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TCMT219 | Cytochrome P450 1A2 | Homo sapiens |
IC50: 795 (nM), Ref: 20696580 |
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TCMT215 | Cytochrome P450 1A1 | Homo sapiens |
IC50: 427 (nM), Ref: 20696580 |
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TCMT257 | Cytochrome P450 1B1 | Homo sapiens |
IC50: 25 (nM), Ref: 20696580 |
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TCMT265 | Glycogen synthase kinase-3 beta | Homo sapiens |
IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y |
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TCMT131 | Acetylcholinesterase | Homo sapiens |
IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y |
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TCMT260 | Tyrosine-protein kinase receptor FLT3 | Homo sapiens |
IC50: 1450 (nM), Ref: 23411073 |
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TCMT128 | Tankyrase-2 | Homo sapiens |
IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272 |
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TCMT129 | Tankyrase-1 | Homo sapiens |
IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272 |
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TCMT592 | Xanthine dehydrogenase | Homo sapiens |
Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844 |
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TCMT280 | Aldo-keto reductase family 1 member B10 | Homo sapiens |
Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431 |
