Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC61	TCMT193	Nuclear factor NF-kappa-B p65 subunit	Homo sapiens	IC50: 250 (nM), Ref: 21513293
TCMC61	TCMT194	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens	IC50: 80 (nM), Ref: 25529738 IC50: 11 (nM), Ref: 26481152 IC50: 8.1 (nM), Ref: 26481152 IC50: 9 (nM), Ref: 27448772
TCMC61	TCMT80	MAP kinase ERK2	Homo sapiens	IC50: 6800 (nM), Ref: 25529738
TCMC61	TCMT195	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens	IC50: 80 (nM), Ref: 25529738
TCMC61	TCMT196	Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens	IC50: 1300 (nM), Ref: 25529738
TCMC908	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 6000 (nM), Ref: 15689157 IC50: 6000 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC908	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 2600 (nM), Ref: 15267241 IC50: 1 (nM), Ref: 20413308 IC50: 800 (nM), Ref: 10.1039/C3MD00166K IC50: 500 (nM), Ref: 26301554
TCMC908	TCMT223	Aldose reductase	Homo sapiens	IC50: 8500 (nM), Ref: 18165015
TCMC908	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	IC50: 670 (nM), Ref: 19097799 Ki: 110 (nM), Ref: 19097799
TCMC908	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 153 (nM), Ref: 20696580 IC50: 1290 (nM), Ref: 23600958
TCMC908	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 84 (nM), Ref: 20696580 IC50: 54 (nM), Ref: 20832301 IC50: 570 (nM), Ref: 23600958
TCMC908	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 24 (nM), Ref: 20696580
TCMC908	TCMT87	Cytochrome P450 2C9	Homo sapiens	IC50: 5225 (nM), Ref: 20832301
TCMC908	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5490 (nM), Ref: 22487176 Ki: 5420 (nM), Ref: 22487176
TCMC908	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4380 (nM), Ref: 22487176 Ki: 4310 (nM), Ref: 22487176
TCMC908	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 2650 (nM), Ref: 22487176 Ki: 2710 (nM), Ref: 22487176
TCMC908	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8960 (nM), Ref: 22487176 Ki: 9070 (nM), Ref: 22487176 Ki: 34.7 (nM), Ref: 26498393
TCMC908	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 537.75 (nM), Ref: 26498393
TCMC908	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 171.41 (nM), Ref: 26498393
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2195	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8
TCMC2195	TCMT335	Myeloperoxidase	Homo sapiens	IC50: 770 (nM), Ref: 23581551
TCMC2195	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1700 (nM), Ref: 22696418
TCMC2037	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 9920 (nM), Ref: 18501600 Ki: 9900 (nM), Ref: 18579385 Ki: 9900 (nM), Ref: 26520662
TCMC2037	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 7120 (nM), Ref: 18501600 Ki: 7100 (nM), Ref: 18579385 Ki: 7100 (nM), Ref: 26520662
TCMC2037	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8800 (nM), Ref: 18579385
TCMC962	TCMT45	Beta amyloid A4 protein	Homo sapiens	Ki: 0.208 (nM), Ref: 17004725 IC50: 800 (nM), Ref: 17270435 IC50: 3900 (nM), Ref: 26099993
TCMC962	TCMT566	Nitric oxide synthase, inducible	Homo sapiens	IC50: 6000 (nM), Ref: 18077363
TCMC962	TCMT87	Cytochrome P450 2C9	Homo sapiens	IC50: 4300 (nM), Ref: 18249473
TCMC962	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 8500 (nM), Ref: 19128977
TCMC962	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2410 (nM), Ref: 20674354
TCMC962	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 380 (nM), Ref: 20674354
TCMC962	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 4970 (nM), Ref: 20674354
TCMC962	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9460 (nM), Ref: 20674354
TCMC962	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 9940 (nM), Ref: 20674354
TCMC962	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 9300 (nM), Ref: 20674354
TCMC962	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4050 (nM), Ref: 20674354
TCMC962	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 3480 (nM), Ref: 20674354
TCMC962	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 6850 (nM), Ref: 20674354
TCMC962	TCMT44	Glyoxalase I	Homo sapiens	Ki: 10000 (nM), Ref: 21237663
TCMC962	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 7410 (nM), Ref:
TCMC962	TCMT46	Coagulation factor III	Homo sapiens	IC50: 199.63 (nM), Ref: 10.1007/s00044-012-0330-5 IC50: 199.63 (nM), Ref: 23199480
TCMC962	TCMT423	Epidermal growth factor receptor erbB1	Homo sapiens	IC50: 8600 (nM), Ref: 23245570
TCMC962	TCMT174	11-beta-hydroxysteroid dehydrogenase 1	Homo sapiens	IC50: 4501 (nM), Ref: 23800686
TCMC962	TCMT570	Aminopeptidase N	Homo sapiens	IC50: 10000 (nM), Ref: 23860593
TCMC962	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 3900 (nM), Ref: 24920381 IC50: 500 (nM), Ref: 24920381 IC50: 600 (nM), Ref: 24920381 IC50: 600 (nM), Ref: 24920381 IC50: 600 (nM), Ref: 24920381
TCMC962	TCMT164	Cyclooxygenase-1	Homo sapiens	IC50: 8100 (nM), Ref: 24920381
TCMC962	TCMT301	Prostaglandin E synthase	Homo sapiens	IC50: 600 (nM), Ref: 24920381 IC50: 1200 (nM), Ref: 24920381
TCMC962	TCMT3	Arachidonate 15-lipoxygenase	Homo sapiens	IC50: 1200 (nM), Ref: 24920381
TCMC962	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5300 (nM), Ref: 25088549
TCMC962	TCMT565	Histone acetyltransferase p300	Homo sapiens	IC50: 6500 (nM), Ref: 25730130
TCMC1429	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 2700 (nM), Ref: 17378609
TCMC1429	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 1050 (nM), Ref: 18533708
TCMC1429	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 360 (nM), Ref: 18533708
TCMC1429	TCMT187	Androgen Receptor	Homo sapiens	IC50: 9700 (nM), Ref: 19592245
TCMC1429	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 716 (nM), Ref: 20696580
TCMC1429	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 632 (nM), Ref: 20696580
TCMC1429	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 47 (nM), Ref: 20696580
TCMC1429	TCMT223	Aldose reductase	Homo sapiens	IC50: 10000 (nM), Ref: 22261024
TCMC1429	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 2320 (nM), Ref: 23411073
TCMC1429	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 9640 (nM), Ref: 23656512
TCMC1429	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 10000 (nM), Ref: 26322379
TCMC1429	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9525.7 (nM), Ref: 26498393
TCMC1429	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 25 (nM), Ref: 26498393
TCMC1429	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 145.9 (nM), Ref: 26498393
TCMC1429	TCMT159	Tyrosinase	Homo sapiens	IC50: 1000 (nM), Ref: 26841168
TCMC42	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 8390 (nM), Ref: 26696252
TCMC42	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2540 (nM), Ref: 26696252
TCMC694	TCMT230	Estradiol 17-beta-dehydrogenase 3	Homo sapiens	IC50: 758 (nM), Ref: 11086723 IC50: 758 (nM), Ref: 16078844
TCMC694	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 20 (nM), Ref: 8035427 Ki: 35 (nM), Ref: 26469743
TCMC1501	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 2100 (nM), Ref: 18042388 IC50: 340 (nM), Ref: 18778944
TCMC43	TCMT301	Prostaglandin E synthase	Homo sapiens	IC50: 220 (nM), Ref: 26588603 IC50: 200 (nM), Ref: 10.1039/C5MD00278H
TCMC43	TCMT565	Histone acetyltransferase p300	Homo sapiens	IC50: 6500 (nM), Ref: 26701186
TCMC43	TCMT208	Monoamine oxidase A	Homo sapiens	Ki: 710 (nM), Ref: 26819666
TCMC43	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 3100 (nM), Ref: 27190601 IC50: 1500 (nM), Ref: 27190601
TCMC2142	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 600 (nM), Ref: 6827528
TCMC2142	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 10000 (nM), Ref: 14552748
TCMC2142	TCMT187	Androgen Receptor	Homo sapiens	IC50: 3.9 (nM), Ref: 15456242 IC50: 2.7 (nM), Ref: 16309907 IC50: 4.571 (nM), Ref: 22746350 IC50: 4.17 (nM), Ref: 25646649 IC50: 4.27 (nM), Ref: 25646649
TCMC2142	TCMT99	Testis-specific androgen-binding protein	Homo sapiens	IC50: 14 (nM), Ref: 17149875
TCMC2142	TCMT725	Voltage-gated L-type calcium channel alpha-1C subunit	Homo sapiens	IC50: 34 (nM), Ref: 22761000 IC50: 38.4 (nM), Ref: 22761000
TCMC876	TCMT560	Coagulation factor X	Homo sapiens	IC50: 720 (nM), Ref: 9834152 Ki: 450 (nM), Ref: 9834152
TCMC1624	TCMT560	Coagulation factor X	Homo sapiens	IC50: 280 (nM), Ref: 9834152 Ki: 690 (nM), Ref: 9834152
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC1399	TCMT223	Aldose reductase	Homo sapiens	IC50: 320 (nM), Ref: 22261024
TCMC1982	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302
TCMC1982	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208
TCMC1982	TCMT223	Aldose reductase	Homo sapiens	IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999
TCMC1982	TCMT44	Glyoxalase I	Homo sapiens	IC50: 3200 (nM), Ref: 18258440
TCMC1982	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 1540 (nM), Ref: 18533708
TCMC1982	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7890 (nM), Ref: 20185318
TCMC1982	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8100 (nM), Ref: 20185318
TCMC1982	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2540 (nM), Ref: 20185318
TCMC1982	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2680 (nM), Ref: 20185318
TCMC1982	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6810 (nM), Ref: 20185318
TCMC1982	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6170 (nM), Ref: 20185318
TCMC1982	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4840 (nM), Ref: 20185318
TCMC1982	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7000 (nM), Ref: 20185318
TCMC1982	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9390 (nM), Ref: 20185318
TCMC1982	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 5410 (nM), Ref: 20185318
TCMC1982	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 12 (nM), Ref: 20413308
TCMC1982	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 4097 (nM), Ref: 20696580 IC50: 1550 (nM), Ref: 22328583
TCMC1982	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1191 (nM), Ref: 20696580
TCMC1982	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 77 (nM), Ref: 20696580
TCMC1982	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 6680 (nM), Ref: 22658537
TCMC1982	TCMT320	Matrix metalloproteinase 3	Homo sapiens	IC50: 5570 (nM), Ref: 22658537
TCMC1982	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 1610 (nM), Ref: 22658537
TCMC1982	TCMT322	Matrix metalloproteinase 13	Homo sapiens	IC50: 8460 (nM), Ref: 22658537
TCMC1982	TCMT422	CaM kinase II beta	Homo sapiens	IC50: 3000 (nM), Ref: 21798748
TCMC1982	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y IC50: 6500 (nM), Ref: 26003344
TCMC1982	TCMT784	Vasopressin V2 receptor	Homo sapiens	IC50: 7000 (nM), Ref: 23437772 IC50: 6309.57 (nM), Ref: 23437772
TCMC1982	TCMT785	Interleukin-8 receptor A	Homo sapiens	IC50: 4500 (nM), Ref: 23437772 IC50: 5011.87 (nM), Ref: 23437772
TCMC1982	TCMT786	C-C chemokine receptor type 4	Homo sapiens	IC50: 10000 (nM), Ref: 23437772
TCMC1982	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 590 (nM), Ref: 23411073
TCMC1982	TCMT601	Thrombin	Homo sapiens	IC50: 1500 (nM), Ref: 24610996
TCMC1982	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 280 (nM), Ref: 24328302
TCMC1982	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 120 (nM), Ref: 24328302
TCMC1982	TCMT791	Protein kinase N1	Homo sapiens	IC50: 5800 (nM), Ref: 24328302
TCMC1982	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 5750 (nM), Ref: 24328302
TCMC1982	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 4230 (nM), Ref: 24328302
TCMC1982	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 5730 (nM), Ref: 24328302
TCMC1982	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 24328302
TCMC1982	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 300 (nM), Ref: 24328302
TCMC1982	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 1200 (nM), Ref: 24328302
TCMC1982	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 960 (nM), Ref: 24328302
TCMC1982	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 910 (nM), Ref: 24328302
TCMC1982	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 5090 (nM), Ref: 24328302
TCMC1982	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 3320 (nM), Ref: 24328302
TCMC1982	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 5390 (nM), Ref: 24328302
TCMC1982	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 280 (nM), Ref: 25060641 IC50: 3500 (nM), Ref: 27162124
TCMC1982	TCMT793	Liver glycogen phosphorylase	Homo sapiens	IC50: 4800 (nM), Ref: 25092521
TCMC1982	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2110 (nM), Ref: 22328583
TCMC1982	TCMT217	Cytochrome P450 2C8	Homo sapiens	IC50: 1390 (nM), Ref: 22328583
TCMC1982	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 8900 (nM), Ref: 26322379
TCMC469	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 100 (nM), Ref: 22921742
TCMC2196	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282
TCMC2196	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 150 (nM), Ref: 22819942
TCMC2196	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220
TCMC124	TCMT194	Mitogen-activated protein kinase kinase kinase 7	Homo sapiens	IC50: 1300 (nM), Ref: 26481152
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC418	TCMT223	Aldose reductase	Homo sapiens	IC50: 78 (nM), Ref: 22236472
TCMC418	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 240 (nM), Ref: 22236472
TCMC418	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4700 (nM), Ref: 22921742
TCMC1153	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7700 (nM), Ref: 22668600
TCMC1153	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8600 (nM), Ref: 22668600
TCMC1153	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 22668600
TCMC1153	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8700 (nM), Ref: 22668600
TCMC1153	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4800 (nM), Ref: 22668600
TCMC1153	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 7900 (nM), Ref: 22668600
TCMC1105	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 2000 (nM), Ref: 19414254
TCMC1105	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 2500 (nM), Ref: 27173800
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC90	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2400 (nM), Ref: 14592472
TCMC770	TCMT588	D-amino-acid oxidase	Homo sapiens	Ki: 7000 (nM), Ref: 23391306 IC50: 2089.3 (nM), Ref: 23631755 Ki: 2000 (nM), Ref: 23631755

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC908	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 11.62 (ug/ml), Ref: 20116898
TCMC962	TCMT1104	Sortase	Staphylococcus aureus	IC50: 13.8 (ug/ml), Ref: 19269184
TCMC962	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 51.3 (ug/ml), Ref: 16643034
TCMC962	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 1 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC1429	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 16.77 (ug/ml), Ref: 20116898
TCMC1399	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1136	Neuraminidase	Influenza A virus	IC50: 3.42 (ug/ml), Ref: 21123068 IC50: 3.48 (ug/ml), Ref: 21123068 IC50: 8.41 (ug/ml), Ref: 21123068 IC50: 9.69 (ug/ml), Ref: 21123068 IC50: 10.56 (ug/ml), Ref: 21123068
TCMC1399	TCMT1121	Sialidase	Clostridium perfringens	IC50: 11.28 (ug/ml), Ref: 21123068
TCMC1982	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 17.65 (ug/ml), Ref: 20116898
TCMC469	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 5.4 (ug/ml), Ref: 16643034
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC908	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 11170636 MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1901	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1236	Mycobacterium bovis	Mycobacterium bovis BCG	MIC: 26 (ug/ml), Ref: 18849164
TCMC1901	TCMT1217	Bacillus anthracis	Bacillus anthracis	MIC: 8 (ug/ml), Ref: 18849164
TCMC1901	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1191	Bacillus megaterium	Bacillus megaterium	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 8 (ug/ml), Ref: 18849164
TCMC1901	TCMT1260	Streptococcus agalactiae	Streptococcus agalactiae	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1322	Streptococcus mitis	Streptococcus mitis	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1410	Listeria monocytogenes	Listeria monocytogenes	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1323	Corynebacterium pseudodiphtheriticum	Corynebacterium pseudodiphtheriticum	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1324	Corynebacterium diphtheriae	Corynebacterium diphtheriae	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1319	Corynebacterium xerosis	Corynebacterium xerosis	MIC: 16 (ug/ml), Ref: 18849164
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC962	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 19299148 IC50: 3.5 (ug/ml), Ref: 19299148
TCMC962	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 4.2 (ug/ml), Ref: 19299148 IC50: 3.5 (ug/ml), Ref: 19299148
TCMC962	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 100 (ug/ml), Ref: 20691508
TCMC962	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 5 (ug/ml), Ref: 19204190 MIC: 15 (ug/ml), Ref: 19204190 MIC: 50 (ug/ml), Ref: 19204190 MIC: 30 (ug/ml), Ref: 19204190
TCMC962	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 30 (ug/ml), Ref: 18284200
TCMC962	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 25938986 MIC: 32 (ug/ml), Ref: 25938986
TCMC1429	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 7.93 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1399	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 62.5 (ug/ml), Ref: 18951808
TCMC1399	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 18951808 MIC: 31.25 (ug/ml), Ref: 22169259 MIC: 62.5 (ug/ml), Ref: 22169259 MIC: 15.6 (ug/ml), Ref: 25137491
TCMC1982	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812 MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 50 (ug/ml), Ref: 12762812
TCMC1982	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 29.5 (ug/ml), Ref: 12398543 IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 64 (ug/ml), Ref: 20655215 MIC: 64 (ug/ml), Ref: 21534606
TCMC1982	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 6 (ug/ml), Ref: 17394331
TCMC1982	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC2196	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 10 (ug/ml), Ref: 22819942 MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 1 (ug/ml), Ref: 23360475 MIC: 1 (ug/ml), Ref: 26253635
TCMC2196	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 6 (ug/ml), Ref: 26253635
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC1105	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 51.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 50.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1105	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 23534483
TCMC1105	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 1 (ug/ml), Ref: 23534483
TCMC1105	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 23534483 MIC: 4 (ug/ml), Ref: 23534483
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1889	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1982	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 22 (nM), Ref: 17263522
TCMC962	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 10.2 (nM), Ref: 17503850
TCMC962	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 37 (nM), Ref: 20034711
TCMC962	TCMT1313	Human immunodeficiency virus 2	Human immunodeficiency virus type 2 (ISOLATE ROD)	IC50: 37 (nM), Ref: 20034711