Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC1714	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 1522.67 (nM), Ref:
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1871	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9200 (nM), Ref: 20185318 Ki: 9200 (nM), Ref: 20590092 Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9200 (nM), Ref: 23265898 Ki: 9200 (nM), Ref: 23010455 Ki: 9200 (nM), Ref: 24189056
TCMC1871	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8800 (nM), Ref: 20185318 Ki: 8800 (nM), Ref: 20590092 Ki: 8800 (nM), Ref: 20674354 Ki: 8800 (nM), Ref: 21282059 Ki: 8800 (nM), Ref: 23265898 Ki: 8800 (nM), Ref: 23010455 Ki: 8800 (nM), Ref: 24189056 Ki: 8800 (nM), Ref: 26520662
TCMC1871	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9500 (nM), Ref: 20185318 Ki: 9500 (nM), Ref: 20590092 Ki: 9500 (nM), Ref: 20674354 Ki: 9500 (nM), Ref: 23010455
TCMC1871	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 2700 (nM), Ref: 20185318 Ki: 2700 (nM), Ref: 20590092 Ki: 2700 (nM), Ref: 20674354 Ki: 2700 (nM), Ref: 23010455
TCMC1871	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 5500 (nM), Ref: 20185318 Ki: 5500 (nM), Ref: 20590092 Ki: 5500 (nM), Ref: 20674354 Ki: 5500 (nM), Ref: 21282059 Ki: 5500 (nM), Ref: 21332115 Ki: 5500 (nM), Ref: 23265898 Ki: 5500 (nM), Ref: 23265903 Ki: 5500 (nM), Ref: 23010455 Ki: 5500 (nM), Ref: 24189056 Ki: 5500 (nM), Ref: 26073005 Ki: 5500 (nM), Ref: 26520662
TCMC2119	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9140 (nM), Ref: 20185318
TCMC2119	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9010 (nM), Ref: 20185318
TCMC2119	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8200 (nM), Ref: 20185318
TCMC2119	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7810 (nM), Ref: 20185318
TCMC2119	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7550 (nM), Ref: 20185318
TCMC2119	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6340 (nM), Ref: 20185318
TCMC2119	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8580 (nM), Ref: 20185318
TCMC2119	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3190 (nM), Ref: 20185318
TCMC2119	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 4150 (nM), Ref: 20185318
TCMC891	TCMT598	DNA topoisomerase I	Homo sapiens	IC50: 50 (nM), Ref: 1324981 IC50: 100 (nM), Ref: 1324981
TCMC1617	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 1555.01 (nM), Ref:
TCMC1112	TCMT203	Glucose-6-phosphate 1-dehydrogenase	Homo sapiens	Ki: 3400 (nM), Ref: 19231202 Ki: 3000 (nM), Ref: 19231202 IC50: 9400 (nM), Ref: 22506561
TCMC1041	TCMT636	DNA polymerase alpha subunit	Homo sapiens	Ki: 830 (nM), Ref: 1705574
TCMC1041	TCMT17	DNA polymerase beta	Homo sapiens	Ki: 390 (nM), Ref: 1705574
TCMC2124	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 4703 (nM), Ref:
TCMC2124	TCMT289	Thromboxane-A synthase	Homo sapiens	IC50: 325 (nM), Ref:
TCMC143	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 1610 (nM), Ref:
TCMC1102	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 7500 (nM), Ref: 16610779
TCMC1102	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 40 (nM), Ref: 19414254
TCMC1102	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2320 (nM), Ref: 20185318
TCMC1102	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2180 (nM), Ref: 20185318
TCMC1102	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC1102	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7590 (nM), Ref: 20185318
TCMC1102	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7060 (nM), Ref: 20185318
TCMC1102	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6320 (nM), Ref: 20185318 Ki: 8790 (nM), Ref: 22892213
TCMC1102	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9370 (nM), Ref: 20185318
TCMC1102	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8910 (nM), Ref: 20185318
TCMC1102	TCMT753	Mothers against decapentaplegic homolog 3	Homo sapiens	IC50: 142 (nM), Ref:
TCMC1102	TCMT721	Heat shock 70 kDa protein 1	Homo sapiens	IC50: 760 (nM), Ref:
TCMC1102	TCMT189	Dual specificity protein phosphatase 3	Homo sapiens	IC50: 1230 (nM), Ref: IC50: 980 (nM), Ref:
TCMC1102	TCMT223	Aldose reductase	Homo sapiens	IC50: 200 (nM), Ref: 22261024
TCMC1102	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 3340 (nM), Ref: 22377675
TCMC1102	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 510 (nM), Ref: 22377675
TCMC1102	TCMT354	Serine/threonine-protein kinase Aurora-A	Homo sapiens	IC50: 2480 (nM), Ref: 22377675
TCMC1102	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 2500 (nM), Ref: 22377675
TCMC1102	TCMT626	Serine/threonine-protein kinase B-raf	Homo sapiens	IC50: 1760 (nM), Ref: 22377675
TCMC1102	TCMT423	Epidermal growth factor receptor erbB1	Homo sapiens	IC50: 690 (nM), Ref: 22377675
TCMC1102	TCMT418	Ephrin type-B receptor 4	Homo sapiens	IC50: 1830 (nM), Ref: 22377675
TCMC1102	TCMT704	Receptor protein-tyrosine kinase erbB-2	Homo sapiens	IC50: 3540 (nM), Ref: 22377675
TCMC1102	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 3110 (nM), Ref: 22377675
TCMC1102	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 250 (nM), Ref: 22377675
TCMC1102	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 800 (nM), Ref: 22377675
TCMC1102	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 790 (nM), Ref: 22377675
TCMC1102	TCMT457	Vascular endothelial growth factor receptor 3	Homo sapiens	IC50: 1540 (nM), Ref: 22377675
TCMC1102	TCMT377	Insulin receptor	Homo sapiens	IC50: 340 (nM), Ref: 22377675
TCMC1102	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 22377675
TCMC1102	TCMT536	Platelet-derived growth factor receptor beta	Homo sapiens	IC50: 1300 (nM), Ref: 22377675
TCMC1102	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 3340 (nM), Ref: 22377675
TCMC1102	TCMT755	Serine/threonine-protein kinase PLK4	Homo sapiens	IC50: 2970 (nM), Ref: 22377675
TCMC1102	TCMT502	Tyrosine-protein kinase TIE-2	Homo sapiens	IC50: 260 (nM), Ref: 22377675
TCMC1102	TCMT756	Mitogen-activated protein kinase kinase kinase 8	Homo sapiens	IC50: 2370 (nM), Ref: 22377675
TCMC1102	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 100 (nM), Ref: 24900447
TCMC1102	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8150 (nM), Ref: 22892213
TCMC1102	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4240 (nM), Ref: 22892213
TCMC1102	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 3900 (nM), Ref: 24835197
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1155	TCMT230	Estradiol 17-beta-dehydrogenase 3	Homo sapiens	IC50: 330 (nM), Ref: 11086723 IC50: 330 (nM), Ref: 16078844
TCMC1597	TCMT807	Solute carrier family 22 member 12	Homo sapiens	IC50: 2000 (nM), Ref: 17325024 Ki: 5740 (nM), Ref: 17325024
TCMC1597	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2927.18 (nM), Ref:
TCMC1597	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 2988.26 (nM), Ref:
TCMC1597	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 1600 (nM), Ref: 24900447
TCMC1597	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 1600 (nM), Ref: 26322379
TCMC1597	TCMT283	Receptor-type tyrosine-protein phosphatase S	Homo sapiens	IC50: 4300 (nM), Ref: 26602279
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC1966	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 410 (nM), Ref: 24835197
TCMC1898	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 7906 (nM), Ref: 20696580
TCMC1898	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 1679 (nM), Ref: 20696580
TCMC1898	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1491 (nM), Ref: 20696580
TCMC1898	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 900 (nM), Ref: 10.1039/C3MD00166K
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1203	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 8000 (nM), Ref: 10.1039/C4MD00086B
TCMC1516	TCMT44	Glyoxalase I	Homo sapiens	IC50: 7700 (nM), Ref: 18258440
TCMC1516	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 3370 (nM), Ref: 20696580
TCMC1516	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1249 (nM), Ref: 20696580
TCMC1516	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 79 (nM), Ref: 20696580
TCMC1516	TCMT83	Lymphocyte differentiation antigen CD38	Homo sapiens	IC50: 8200 (nM), Ref: 21641214
TCMC1516	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 3610 (nM), Ref: 22658537
TCMC1516	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 5620 (nM), Ref: 22658537
TCMC1516	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 980 (nM), Ref: 22658537
TCMC1516	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1516	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 830 (nM), Ref: 23411073
TCMC1516	TCMT127	Poly [ADP-ribose] polymerase-1	Homo sapiens	IC50: 4265.8 (nM), Ref: 23574272 IC50: 4200 (nM), Ref: 23574272
TCMC1516	TCMT128	Tankyrase-2	Homo sapiens	IC50: 1071.52 (nM), Ref: 23574272 IC50: 1100 (nM), Ref: 23574272
TCMC1516	TCMT129	Tankyrase-1	Homo sapiens	IC50: 2398.83 (nM), Ref: 23574272 IC50: 2400 (nM), Ref: 23574272
TCMC1516	TCMT223	Aldose reductase	Homo sapiens	IC50: 600 (nM), Ref: 23683835 IC50: 3200 (nM), Ref: 26529431
TCMC1516	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1600 (nM), Ref: 24368208
TCMC1516	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 6400 (nM), Ref: 24878198
TCMC1516	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 2900 (nM), Ref: 25019478 IC50: 7800 (nM), Ref: 26096677
TCMC1516	TCMT100	Transthyretin	Homo sapiens	IC50: 7000 (nM), Ref: 26214366
TCMC1516	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3691.6 (nM), Ref: 26498393
TCMC1516	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.7 (nM), Ref: 26498393
TCMC1516	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 60.3 (nM), Ref: 26498393
TCMC1516	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 293 (nM), Ref: 26498393
TCMC1516	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 9200 (nM), Ref: 26529431
TCMC1977	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 7410 (nM), Ref: 21669522
TCMC1977	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 540 (nM), Ref: 21669522
TCMC1977	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 520 (nM), Ref: 21669522
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1133	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 1.3 (nM), Ref: 15203155 IC50: 3 (nM), Ref: 10673099 IC50: 1.3 (nM), Ref: 15203156 Ki: 100 (nM), Ref: 12954056 IC50: 2 (nM), Ref: 12749898 IC50: 5.9 (nM), Ref: 10447957 IC50: 1.3 (nM), Ref: 15745820 IC50: 1.3 (nM), Ref: 15664843 IC50: 1.3 (nM), Ref: 15582421 IC50: 1.3 (nM), Ref: 15225685 IC50: 1.3 (nM), Ref: 15225686 IC50: 3.2 (nM), Ref: 15341953 IC50: 3.2 (nM), Ref: 15456246 IC50: 3.2 (nM), Ref: 15876535 IC50: 3.2 (nM), Ref: 15943471 IC50: 28 (nM), Ref: 15658851 Ki: 1.995 (nM), Ref: 15771467 IC50: 3.2 (nM), Ref: 16098741 IC50: 0.75 (nM), Ref: 16219463 IC50: 1.4 (nM), Ref: 16309907 IC50: 1.35 (nM), Ref: 16412638 IC50: 10 (nM), Ref: 16610787 IC50: 1.3 (nM), Ref: 16632357 IC50: 1.3 (nM), Ref: 16730987 IC50: 46 (nM), Ref: 16942012 IC50: 1.6 (nM), Ref: 16942012 IC50: 1.3 (nM), Ref: 16777408 IC50: 1.2 (nM), Ref: 17149865 IC50: 4.7 (nM), Ref: 17696335 IC50: 3.6 (nM), Ref: 17049855 IC50: 3.2 (nM), Ref: 17188490 IC50: 1 (nM), Ref: 17289385 IC50: 1.4 (nM), Ref: 17448656 IC50: 1.4 (nM), Ref: 17890084 IC50: 4 (nM), Ref: 18760603 Ki: 2 (nM), Ref: 18722117 IC50: 12.5 (nM), Ref: 19836949 IC50: 3.2 (nM), Ref: 19705860 Ki: 0.16 (nM), Ref: 20621492 IC50: 21.04 (nM), Ref: 20812681 IC50: 46 (nM), Ref: 20875743 IC50: 1.3 (nM), Ref: 24315190 IC50: 5.7 (nM), Ref: 25369367 IC50: 0.9 (nM), Ref: 26183544 Ki: 0.21 (nM), Ref: Ki: 0.21 (nM), Ref: IC50: 1.7 (nM), Ref: 27407030
TCMC1133	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 1.1 (nM), Ref: 15203155 IC50: 4 (nM), Ref: 10673099 IC50: 1.1 (nM), Ref: 15203156 Ki: 100 (nM), Ref: 12954056 IC50: 2 (nM), Ref: 12749898 IC50: 1.1 (nM), Ref: 15745820 IC50: 1.1 (nM), Ref: 15664843 IC50: 1.1 (nM), Ref: 15993065 IC50: 1.1 (nM), Ref: 15582421 IC50: 1.1 (nM), Ref: 15225685 IC50: 1.1 (nM), Ref: 15225686 IC50: 3.6 (nM), Ref: 15341953 IC50: 3.6 (nM), Ref: 15456246 IC50: 3.6 (nM), Ref: 15876535 IC50: 3.6 (nM), Ref: 15943471 IC50: 24 (nM), Ref: 15658851 Ki: 3.162 (nM), Ref: 15771467 IC50: 3.6 (nM), Ref: 16098741 IC50: 1.18 (nM), Ref: 16219463 IC50: 1.2 (nM), Ref: 16309907 IC50: 1.2 (nM), Ref: 16412638 IC50: 11 (nM), Ref: 16610787 IC50: 1.2 (nM), Ref: 16632357 IC50: 1.2 (nM), Ref: 16730987 IC50: 1.4 (nM), Ref: 16942012 IC50: 1.1 (nM), Ref: 16777408 IC50: 1.4 (nM), Ref: 17149865 IC50: 16.7 (nM), Ref: 17696335 IC50: 3.2 (nM), Ref: 17049855 IC50: 3.6 (nM), Ref: 17188490 IC50: 1 (nM), Ref: 17289385 IC50: 1.2 (nM), Ref: 17448656 IC50: 1.2 (nM), Ref: 17890084 IC50: 4 (nM), Ref: 18760603 Ki: 2 (nM), Ref: 18722117 IC50: 2.9 (nM), Ref: 19705860 IC50: 10.74 (nM), Ref: 20812681 IC50: 0.046 (nM), Ref: 24315190 IC50: 5.6 (nM), Ref: 25369367 Ki: 0.015 (nM), Ref: Ki: 0.015 (nM), Ref: IC50: 3 (nM), Ref: 27407030
TCMC1133	TCMT187	Androgen Receptor	Homo sapiens	IC50: 19.1 (nM), Ref: 16309907
TCMC1133	TCMT99	Testis-specific androgen-binding protein	Homo sapiens	IC50: 50 (nM), Ref: 17149875
TCMC1133	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 3.6 (nM), Ref: 17482813 IC50: 6 (nM), Ref: 23448346
TCMC1133	TCMT910	Estrogen-related receptor beta	Homo sapiens	IC50: 3.2 (nM), Ref: 17482813 IC50: 8.7 (nM), Ref: 23448346
TCMC1133	TCMT344	Aldehyde oxidase	Homo sapiens	IC50: 80 (nM), Ref: 20853847 Ki: 4400 (nM), Ref: 22996261 Ki: 870 (nM), Ref: 22996261
TCMC1133	TCMT974	G-protein coupled estrogen receptor 1	Homo sapiens	Ki: 5.7 (nM), Ref: 23672690 Ki: 2.7 (nM), Ref: 10.1039/C5MD00455A
TCMC2180	TCMT302	HMG-CoA reductase	Homo sapiens	IC50: 5860 (nM), Ref: 25311563 IC50: 36.31 (nM), Ref: 25311563
TCMC1378	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 8960 (nM), Ref: 22658537
TCMC1378	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 8220 (nM), Ref: 22658537

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2124	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 50 (ug/ml), Ref: 1710653
TCMC2264	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 13.01 (ug/ml), Ref: 22552195 IC50: 11.54 (ug/ml), Ref: 22552195 IC50: 22.45 (ug/ml), Ref: 22552195 IC50: 23.54 (ug/ml), Ref: 22552195
TCMC2264	TCMT1136	Neuraminidase	Influenza A virus	IC50: 13.01 (ug/ml), Ref: 22552195 IC50: 11.54 (ug/ml), Ref: 22552195 IC50: 22.45 (ug/ml), Ref: 22552195 IC50: 23.54 (ug/ml), Ref: 22552195
TCMC1203	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 28.5 (ug/ml), Ref: 9461665
TCMC1516	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.65 (ug/ml), Ref: 20116898
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2384	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 62.5 (ug/ml), Ref: 10395496
TCMC2402	TCMT1251	Candida albicans	Candida albicans	MIC: 31.25 (ug/ml), Ref: 8254344
TCMC2404	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 18710283 MIC: 28 (ug/ml), Ref: 22280816
TCMC2404	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 100 (ug/ml), Ref: 18710283 MIC: 28 (ug/ml), Ref: 22280816
TCMC2439	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 2 (ug/ml), Ref: 9784148
TCMC2477	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 72.5 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1102	TCMT1246	Escherichia coli	Escherichia coli	MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.103 (ug/ml), Ref: 11374952 IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 0.103 (ug/ml), Ref: 11374952 IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 5.5 (ug/ml), Ref: 12502337
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550	TCMT1393	Vibrio sp.	Vibrio sp.	MIC: 15 (ug/ml), Ref: 21865038
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC2566	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1966	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 32 (ug/ml), Ref: 11277742
TCMC1966	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 27.73 (ug/ml), Ref: 19299148
TCMC1898	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC1898	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 80.76 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1898	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 73 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 63.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1203	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 22.6 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2035	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2627	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 64 (ug/ml), Ref: 11277742
TCMC946	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 14510592
TCMC2635	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 0.608 (ug/ml), Ref: 23313632
TCMC2635	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 10.9 (ug/ml), Ref: 23313632
TCMC1516	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 64 (ug/ml), Ref: 12608861 MIC: 4 (ug/ml), Ref: 22677320
TCMC1516	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 18 (ug/ml), Ref: 22677320 MIC: 9 (ug/ml), Ref: 22677320
TCMC1516	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12608861
TCMC1516	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 7 (ug/ml), Ref: 17394331
TCMC1516	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 17.8 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1516	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1516	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 0.8 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1977	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 62.5 (ug/ml), Ref: 19232493
TCMC1977	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 19232493
TCMC1578	TCMT1408	Colletotrichum gloeosporioides	Colletotrichum gloeosporioides	IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578	TCMT1245	Phytophthora cactorum	Phytophthora cactorum	IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC2688	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 14969530
TCMC2688	TCMT1282	Colletotrichum orbiculare	Colletotrichum orbiculare	MIC: 30 (ug/ml), Ref: 14969530
TCMC2696	TCMT1354	Streptococcus mutans UA159	Streptococcus mutans UA159	MIC: 80 (ug/ml), Ref: 10.1007/s00044-011-9658-5
TCMC1738	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001